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Bio vocab Ch.5
Membrane Structure and Function
Question | Answer |
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fluid mosaic | A description of membrane structure, depicting a cellular membrane as a mosaic of diverse protein molecules embedded in a fluid bilayer made of phospholipid molecules. |
selective permeability | A property of biological membranes that allows some substances to cross more easily than others and blocks the passage of other substances altogether. |
diffusion | The spontaneous tendency of a substance to move down its concentration gradient from where it is more concentrated to where it is less concentrated. |
concentration gradient | An increase or decrease in the density of a chemical substance in an area. Cells often maintain concentration gradients of ions across their membranes. When a gradient exists, substances tend to move from where they are more concentrated to where they are |
passive transport | The diffusion of a substance across a biological membrane, without any input of energy. |
osmosis | The diffusion of water across a selectively permeable membrane. |
tonicity | The ability of a solution surrounding a cell to cause that cell to gain or lose water. |
isotonic solution | A solution having the same solute concentration as another solution, thus having no effect on passage of water in or out of the cell. |
hypotonic solution | In comparing two solutions, the one with the lower concentration of solutes; cells in such a solution will take up water from their surroundings. |
hypertonic | In comparing two solutions, the one with the greater concentration of solutes; cells in such a solution will lose water to their surroundings. |
osmoregulation | Method by which organisms regulate solute concentrations and balance the gain and loss of water. |
facilitated diffusion | The passage of a substance through a specific transport protein across a biological membrane down its concentration gradient. |
aquaporins | A transport protein in the plasma membrane of some plant or animal cells that facilitates the diffusion of water across the membrane (osmosis). |
active transport | The movement of a substance across a biological membrane against its concentration gradient, aided by specific transport proteins and requiring input of energy (often as ATP). |
exocytosis | The movement of materials out of the cytoplasm of a cell by the fusion of vesicles with the plasma membrane. |
endocytosis | Cellular uptake of molecules or particles via formation of new vesicles from the plasma membrane. |
phagocytosis | Cellular "eating"; a type of endocytosis whereby a cell engulfs macromolecules, other cells, or particles into its cytoplasm. |
pinocytosis | Cellular "drinking"; a type of endocytosis in which the cell takes fluid and dissolved solutes into small membranous vesicles. |
receptor-mediated endocytosis | The movement of specific molecules into a cell by the inward budding of membranous vesicles. The vesicles contain proteins with receptor sites specific to the molecules being taken in. |
energy | The capacity to perform work, or to rearrange matter. |
kinetic energy | The energy of motion; the energy of a mass of matter that is moving. Moving matter does work by imparting motion to other matter. |
heat | Thermal energy; the amount of energy associated with the movement of the atoms and molecules in a body of matter. Heat is energy in its most random form. |
potential energy | The energy that matter possesses because of its location or arrangement. Water behind a dam and chemical bonds possess potential energy. |
chemical energy | Energy available in molecules for release in a chemical reaction; a form of potential energy. |
thermodynamics | The study of energy transformation that occurs in a collection of matter. See first law of thermodynamics; second law of thermodynamics. |
first law of thermodynamics | The principle of conservation of energy. Energy can be transferred and transformed, but it cannot be created or destroyed. |
entropy | A measure of disorder. One form of disorder is heat, which is random molecular motion. |
second law of thermodynamics | The principle whereby every energy conversion reduces the order of the universe, increasing its entropy. Ordered forms of energy are at least partly converted to heat. |
exergonic reaction | An energy-releasing chemical reaction in which the reactants contain more potential energy than the products. The reaction releases an amount of energy equal to the difference in potential energy between the reactants and the products. |
cellular respiration | The aerobic harvesting of energy from food molecules; the energy-releasing chemical breakdown of food molecules, such as glucose, and the storage of potential energy in a form that cells can use to perform work; involves glycolysis, the citric acid cycle, |
endergonic reactions | An energy-requiring chemical reaction, which yields products with more potential energy than the reactants. The amount of energy stored in the products equals the difference between the potential energy in the reactants and that in the products. |
metabolism | The totality of an organism's chemical reactions. |
metabolic pathway | A series of chemical reactions that either builds a complex molecule or breaks down a complex molecule into simpler compounds. |
energy coupling | In cellular metabolism, the use of energy released from an exergonic reaction to drive an endergonic reaction. |
ATP | Main energy source for cells. |
phosphorylation | The transfer of a phosphate group, usually from ATP, to a molecule. Nearly all cellular work depends on ATP energizing other molecules by phosphorylation. |
energy of activation (Ea) | The amount of energy that reactants must absorb before a chemical reaction will start. |
enzymes | A protein (or RNA molecule) that serves as a biological catalyst, changing the rate of a chemical reaction without itself being changed into a different molecule in the process. |
substrate | 1) A specific substance (reactant) on which an enzyme acts. Each enzyme recognizes only the specific substrate or substrates of the reaction it catalyzes. (2) A surface in or on which an organism lives. |
active site | The part of an enzyme molecule where a substrate molecule attaches (by means of weak chemical bonds); typically, a pocket or groove on the enzyme's surface. |
induced fit | The change in shape of the active site of an enzyme, induced by entry of the substrate so that it binds more snugly to the substrate. |
competitive inhibitor | A substance that reduces the activity of an enzyme by binding to the enzyme's active site in place of the substrate. A competitive inhibitor's structure mimics that of the enzyme's substrate. |
noncompetitive inhibitor | A substance that impedes the activity of an enzyme without entering an active site. By binding elsewhere on the enzyme, a noncompetitive inhibitor changes the shape of the enzyme so that the active site no longer functions. |
cofactors | A nonprotein molecule or ion that is required for the proper functioning of an enzyme. See also coenzyme. |
coenzyme | An organic molecule serving as a cofactor. Most vitamins function as coenzymes in important metabolic reactions. |
feedback inhibition | A method of metabolic control in which a product of a metabolic pathway acts as an inhibitor of an enzyme within that pathway. |