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Types of Anemia
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Microcytic Anemia
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ANEMIA

QuestionAnswer
Types of Anemia Microcytic, Normocytic, Macrocytic
Microcytic Anemia Mean cell volume is lower than normal. Iron deficiency, hemoglobinopathy, chronic disease, lead disease.
Normocytic Anemia Mean cell volume is normal. Acute bleeding, aplastic, hemolytic, low erythropoietin, malignancy.
Macrocytic Anemia Low vitamin B12, low folate.
Anemia vs. Polycythemia Anemia = deficit of RBCs
Vitamin B12 essential for synthesis of DNA; without B12 cells cannot divide properly
Folate necessary for synthesis of nucleic acids and nuclear maturation of RBCs; involved with DNA replication
Iron essential to hemoglobin. iron is what carries the oxygen in the RBC.
Stem Cells RBCs are developed from stem cells
Erythropoietin kidney hormone that synthesizes RBCs; action on stem cells turns them into mature RBCs
Hemoglobin in Mature RBCs in each mature RBC = 300 hemoglobin molecules. compromise 90% of dry weight
Hemoglobin Catabolism Hemoglobin is broken into globin and heme (biliverdin). Biliverdin is broken into bilirubin which is then broken into bile and iron. Both globin and iron are recylced.
General Signs of Anemia increased respiration, increased HR, fatigue, decreased activity, pallor, transient heart murmor
Created by: Dance22
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