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DU PA MS
Duke PA Multiple Sclerosis
Question | Answer |
---|---|
MS is an __ disorder of the CNS that affects physical, cognitive, and psychological function | inflammatory demyelinating |
median onset of age for MS is __ years | 30 |
MS is more common in __ | women |
common manifestations of MS | optic neuritis, transverse myelitis, paresthesias, ataxia, weakness or incoordination, spasticity, cognitive impairment |
the hallmark for the diagnosis of MS | abnormalities of the CNS separated by place and time |
inflammation leads to demylination which leads to __ | axonal loss |
MS is an __ disease | episodic |
at diagnosis 85% of people with MS present with a __ | relapsing form of the disease |
the pattern of MS over time includes | relapses (attacks, disability (gradual progressive deterioration of function), or a combination of both |
very few patients with MS have | benign MS, in which there is complete recovery between relapses |
MS pathophysiology in a nutshell | autoimmune inflammation of the oligodendrocytes, leading to demylination and axonal loss |
relapse of MS is treated with | corticosteroids |