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DU PA MS
Duke PA Multiple Sclerosis
| Question | Answer |
|---|---|
| MS is an __ disorder of the CNS that affects physical, cognitive, and psychological function | inflammatory demyelinating |
| median onset of age for MS is __ years | 30 |
| MS is more common in __ | women |
| common manifestations of MS | optic neuritis, transverse myelitis, paresthesias, ataxia, weakness or incoordination, spasticity, cognitive impairment |
| the hallmark for the diagnosis of MS | abnormalities of the CNS separated by place and time |
| inflammation leads to demylination which leads to __ | axonal loss |
| MS is an __ disease | episodic |
| at diagnosis 85% of people with MS present with a __ | relapsing form of the disease |
| the pattern of MS over time includes | relapses (attacks, disability (gradual progressive deterioration of function), or a combination of both |
| very few patients with MS have | benign MS, in which there is complete recovery between relapses |
| MS pathophysiology in a nutshell | autoimmune inflammation of the oligodendrocytes, leading to demylination and axonal loss |
| relapse of MS is treated with | corticosteroids |