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Patho Kaplan key wor
clinical presentation
Question | Answer |
---|---|
.Cell swelling | Reversible damage/Inhibition of Na/K/ATPase |
BAX and BAK | Pro-apoptotic |
Caspase activation causes | apoptosis |
.Free copper or iron | Free radical production |
Superoxide dismutase | Neutralizes superoxides |
Decrease oxygen content Increase EPO | |
NADPH oxydase reaction produces what | Superoxide by leukocytes |
Glutathione peroxidase | Neutralization of OH. H202. NAPQI |
BCL-2 | Antiapoptotic |
Ca/ATPase inhibition . | Irriversible damage |
Cytochrom C leakage ' | apoptosis |
Most damaging free radical | Hydroxyl free radical |
Leakage of intracellular enzymes . | Membrane damage |
Growth of a tissue by replicating the cells | Hyperplasia |
Low Hb ,SaO2 and PaO2 | |
Decrease arterial flow or venous outflow . | ischemia |
Catalase neutralizes what | H202 to H20 and 02 |
Ionizing radiations ' | Hydroxyl free radical |
Cell death without inflammation ' | Apoptosis |
Coagulative necrosis with cheese like material in the center | Caseous necrosis |
Disordered cell growth | Dysplasia |
Change of one epithelium to a different type as adaptation ' | Metaplasia |
Tissues that can only hypertrophy (3) | Heart. skeletal muscle, neurons |
Leakage of intracellular enzymes . | Membrane damage |
Growth of a tissue by replicating the cells | Hyperplasia |