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Sjogren
Rheumatology
Question | Answer |
---|---|
Defn Sjogren syndrome | inflam dz of exocrine glands (sicca) |
If sjogren sx and no other autoimmune dz = | Primary Sjogren |
If autoimmune dz and sjogren sx = | secondary sjogren |
Sjogren sx | sicca (dry eyes & mouth (xerostomia); parotid enlargement; poss also fatigue/ myalgias (rare: internal organ involvement: lungs, kidneys, etc |
Sjogren: Testing: Eyes: | Schirmer’s test: measures tear production on paper; Rose-Bengal staining: shows corneal damage |
Sjogren: Testing: Mouth: | salivary gland biopsy |
Sjogren: Testing: Labs: | antibodies to Ro and La |
Sjogren: Tx: Keratoconjunctivitis sicca: | ocular lubricants, artificial tears |
Sjogren: Tx: Xerostomia: | liberal fluids; specially-formulated mouthwash, toothpaste, chewing gum (Biotene), oral moisturizers |
Sjogren: Tx: Systemic sx | steroids; NSAIDs; DMAARDs (usually hydroxychloroquine) |
Defn Sjogren syndrome | inflam dz of exocrine glands (sicca); usu middle aged F |
If autoimmune dz and sjogren sx = | secondary sjogren |
Sjogren sx | sicca (dry eyes & mouth (xerostomia); parotid enlargement; poss also fatigue/ myalgias (rare: internal organ involvement: lungs, kidneys, etc |