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First Aid Immunology
Autoantibodies
Question | Answer |
---|---|
SLE | Antinuclear antibodies (ANA) |
Specific for SLE | Anti-dsDNA, Anti-Smith antibodies |
Drug-induced Lupus | Antihistone antibodies |
Rheumatoid Arthritis | Anti-IgG (rheumatoid factor) |
Scleroderma (CREST) | Anticentromere |
Scleroderma (diffuse) | Anti-Scl-70 |
Primary Biliary Cirrhosis | Antimitochondrial (AMA) |
Celiac Disease | Antigliadin, antiendomysial |
Goodpasture's syndrome | Anti-basement membrane |
Pemphigus vulgaris | Anti-desmoglein |
Hashimoto's thyroiditis | Antimicrosomial, antithyroglobulin |
Polymyositis, dermatomyositis | Anti-Jo-1 |
Sjogren's syndrome | Anti-SS-A (anti-Ro), Anti-SS-B (anti-La) |
Mixed Connective Tissue Disease | Anti-U1 RNP (ribonucleoprotein) |
Autoimmune Hepatitis | Anti-smooth muscle |
Type 1 Diabetes Mellitus | Anti-glutamate decarboxylase |
Wegener's Granulomatosis | c-ANCA |
Other vasculitides | p-ANCA |