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| Question | Answer |
|---|---|
| What bacteria looks like Chinese letters | Corynebacter |
| What are the 5 bacteria causing Heart Block | "Lyme Disease Salmonella typhii (typhoid) Chagas Disease (Whipple’s) Legionella Diptheria |
| What bacteria cause Reiter’s Syndrome | Shigella IBD Crohn’s Chlamydia Yersina Reiter & Crohn Saw Yersina and got Chlamyia |
| What are the Low Complement bugs causing Cryoglobuniemia | Influenzae Adenovirus Mycoplasma Hepatitis C EBV I AM HE |
| What are the drugs induced SLE | Hydralazine INH Phenytoin Procainamide Penicillamine Ethosuximide H I PPPE |
| What are the drugs that Blast the BM | "AZT Benzene Chloramphenicol Vinblastine Vinblastine Anilate Bone Cells |
| What are the Comma Shaped bugs | "Vibrio Campylobacter Listeria H. pylori |
| What is the cresent shaped protozoa | Giardia lamblia |
| What bacteria looks like Chinese letters | Corynebacter |
| What are the TB Rx | Rifampin INH Pyrazinamide Ethambutanol Streptomycin |
| What are the 6 Low Complement assocs. with Nephrotic Syndrome | Serum Sickness PSGN SLE SBE Cryoglobinemia MPGN II |
| What drugs Induce p450 | Barbiturates Alcohol Griseofulvin Carbamazapin Rifampine Quinidine Tetracycline Sulfa drugs |
| What drugs Inhibit p450 | INH Dapsone Spirolactones Macrolides Amiodarone Cimetidine Ketoconazole Quinilones |
| What drugs are P450 Dependent | Warfarin Estrogen Phenytoin Theophylline Digoxin |
| What disease is a Neutophil Deficiency | Chronic Granulomatous disease CGD |
| What is another name for CGD | NADPH Oxidase deficiency |
| What are the Side effects of Statins | Myositis Hepatitis Increased liver enzymes |
| What are the painful genital Lesions | Chancroid Herpes Lymphogranuloma inguinale |
| What is the painful chancroid lesion due to | Hemophilus ducreyi |
| What are the 4 hormones with disulfide bonds | Prolactin Insulin GH Inhibin |
| What are the Hookworms | Necatur americanis Enterobius vermicularis Ankylostoma duodenale Trichuris trichurium Ascaris lumbercoides Strongyloides Hooks AS NEAT |
| What are the X-Linked enzyme Deficiencies | G6-PD CGD Pyruvate dehydrogenase Def. Fabry’s Hunter’s Lesch-nyhan |
| HLA-DR2 | Narcolepsy, Allergy, Goodpasture’s, MS |
| HLA-DR3 | DM, Chronic Active Hepatitis, Sjogren’s, SLE, Celiac Sprue |
| What are the actions of Steroids | Kills helper T-cells & eosinophils Inhibits Macrophage migration Inhibits Mast cell degranulation Inhibits Phospholipase A Stimulates protein synthesis Stablizes endothelium |
| What are the causes of Monocytosis | Salmonella (typhoid) TB EBV Listeria Syphillis |
| E. Coli is the most common cause of what | UTI Spontaneous bacterial peritonitis Abdominal abscess Cholecystitis Ascending cholangitis Appendicitis |
| What are the “Big Mama” anaerobes | Strep bovis Clostridium melanogosepticus Bacteriodes fragilis |
| What are the “Big Mama” Rx | Clindamycin Metranidazole Cefoxitin |
| What “big mama” bugs are associated with colon cancer | Strep. Bovis Clostridium melanogosepticus |
| What are psammoma bodies | Calcified CA’s |
| In what diseases are Psammoa Bodies present | Papillary carcinoma of the Thyroid Serous cystadenocarcinoma of the ovary Meningioma Mesothelioma |
| What types of stones are formed from Proteus | Struvite (90%) |
| What type of motility do Proteus have | swarming |
| What are 5 indications of Surgery | Intractable pain Hemorrhage (massive) Obstruction (from scarring) Perforation |
| What drugs cause Cardiac Fibrosis | Adriamycin (Doxyrubicin) Phen-fen |
| What drug is used to tx cardiac fibrosis | Dozaroxsin |
| What is the MCC of any ….penia | "#1 = Virus #2 = Drugs |
| What is seen in the Salmonella Triad | High Fever Rose spots (rash) Intestinal fire |
| What drugs cause Myositis | Rifampin INH Predinsone Statins |
| What are the causes of Eosinophilla | Neoplasms Allergies/Asthma Addison’s Dz Collagen Vascular Dz Parasites |
| What are the Killed Vaccines | SIR Hep A |
| What are the IgA Nephropathies | Henoch-Schoenlein P. (HSP) Alport’s Berger’s |
| What are the Drugs that cause Autoimmune hemolytic anemia | PCN α-methyldopa Cephalosporins Sulfa PTU Anti-malarials Dapsone |
| What are the drugs that cause Autoimmune thrombocytopenia | ASA Heparin Quinidine |
| What is the first MI enzyme to appear | Troponin I |
| What is the 2nd MI enzyme to appear | CK-MB |
| What is the 3rd MI enzyme to appear | LDH |
| What bacteria have Silver Stains | Legionella Pneumocysitis carinii H. pylori Bartonella henseslae (lymph node) Candida (yeast) |
| What drugs inhibit dihydrofolate reductase | Trimethoprim/Sulfamethoxazole "Pyremethamin/Sulfadiazine |
| What drugs cause Pulmonary Fibrosis | Bleomycin Bulsufan Amiodarone Tocainide |
| What are the macrophage deficiency diseases | Chediak-Higashi NADPH-oxidase deficiency |
| What are the 7 Rashes of the Palms & Soles | TSS Rocky Mountain Spotted Fever Coxsackie A (Hand/Foot & mouth dz) Kawasaki Syphillis Scarlet Fever Staph Scalded Skin Syndrome |
| What is the clue for cAMP | Sympathetic CRH (cortisol) Catabolic |
| What is the clue for cGMP | Parasympathetic Anabolic |
| What are the clues for IP3/DAG | "Neurotransmitter GHRH All hypothalamic hormones xc cortisol |
| What is the clue for Ca+ | Used by Gastrin only |
| What is the clue for Ca:Calmodulin | Used by smooth muscle for contraction by distention |
| What is the clue for Tyrosine Kinase | "Used by Insulins |
| What are the T & B cell deficiencies | "WAS SCID CVID HIV HTLV-1 |
| What are the CLUES for WAS | Thrombocytopenia IL-4 Infection Eczema Decrease IgM |
| What are the CLUES for SCID | Framshift/Nonsense mutation Adenosine deaminase deficiency T-cell>B-cell Bacterial infections Fungal infections |
| What are the CLUES for CVID | "Late onset Frameshift/Missense mutation Tyrosine Kinase deficiency |
| What are the inhibitors of Complex 1 of the ETC | Amytal Rotenone |
| What are the inhibitors of Complex 2 of the ETC | Malonate |
| What are the inhibitors of Complex 3 of the ETC | Antimycin D |
| What are the inhibitors of Complex 4 of the ETC | CN- CO Chloramphenicol |
| What are the inhibitors of Complex 5 of the ETC | Oligomycin |
| What are the ETC chemical uncouplers | DNP Free Fatty acids Aspirin |
| What type of uncoupler is Aspirin | Physical uncoupler |
| What are the 4 sources of Renal Acid | Urea cycle Plasma Collecting ducts Glutaminase |
| What are the 2 enzymes needed to make glycogen | "Glycogen synthase Branching enzyme |
| What are the branching enzymes | "Glycogen alpha-1,4 glycosyl transferase Glycogen alpha-1,6 glycosyl transferase |
| What is the rate limiting enzyme in the break down of glycogen | Phosphorylase (Pi) |
| What type of acidosis do you see with obstructive pulmonary dz | Respiratory acidosis |
| What Autoimmune Disease has the following Anti-smith Anti cardiolipin Anti-ds DNA Antibodies | SLE |
| What Autoimmune Disease has the following Anti – histone Antibodies | Drug induced SLE |
| What Autoimmune Disease has the following Anti-topoisomerase Antibodies | PSS (Progressive Systemic Sclerosis) |
| What Autoimmune Disease has the following Anti-centromere Antibodies | CREST |
| What Autoimmune Disease has the following Anti-GBM Antibodies | Goodpasture’s |
| What does Goodpastures have antibody to | Type IV collagen |
| What Autoimmune Disease has the following Anti-mitochondria Antibodies | Primary biliary cirrhosis |
| What Autoimmune Disease has the following Anti-hair follicle Antibodies | Alopecia areata |
| What Autoimmune Disease has the following Anti-IgG Antibodies | Rheumatoid arthritis |
| What Autoimmune Disease has the following Anti-myelin receptors Antibodies | MS |
| What Autoimmune Disease has the following Anti-ACh receptor Antibodies | MG |
| What Autoimmune Disease has the following Anti-ribonuclear protein Antibodies | Mixed Connective Tissue dz (MCTD) |
| What does Pernicious Anemia have antibody to | Intrinsic factor |
| What Autoimmune Disease has the following Anti-epidermal anchoring protein receptors Antibodies | Pemphigus vulgaris |
| What Autoimmune Disease has the following Anti-epidermal basement membrane protein Antibodies | Bullous pemphigoid |
| What do you see with bullous pemphigoid | IgG sub-epidermal blisters Oral blisters |
| HLA-DR2 | Narcolepsy, Allergy, Goodpasture’s, MS |
| HLA-DR3 | DM, Chronic Active Hepatitis, Sjogren’s, SLE, Celiac Sprue |
| HLA-DR3 & 4 | IDDM(Type I) |
| HLA-DR4 | Rheumatoid Arthritis, Pemphigus Vulgaris |
| HLA-DR5 | JRA, Pernicious Anemia |
| HLA-DR7 | Nephrotic Syndrome(Steroid induced) HLA-DR 3 & B8 |
| HLA-A3 | Hemochromatosis(chromo. 6, point mut.-cysteine>tyrosine) |
| HLA-B8 | MG |
| HLA-B13 | Psoriasis |
| HLA-B27 | Psoriais(only if w/arthritis) Ankylosing Spondylitis, IBD, Reiter’s, Postgonococcal Arthritis |
| HLA-BW 47 | 21 alpha Hydroxylas def.(Vit.D) |
| HLA-DR 3 & B8 | Celiac Disease |
Created by:
mcafej02
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