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Promethazine
Question | Answer |
---|---|
Promethazine GENERIC NAME | Promethazine |
Promethazine BRAND NAME | Phenergan |
Promethazine CLASS | Antiemetics, antihistamine, sedative/hypnotics |
Promethazine MECHANISM OF ACTION | Blocks the effects of histamine. Alters the effects of dopamine in the CNS. Possesses significant anticholinergic activity. |
Promethazine INDICATIONS | Treatment of various allergic conditions and motion sickness. Treatment and prevention of N/V |
Promethazine CONTRAINDICATIONS | Narrow-angle glaucoma, comatose patients, children less then 2yr. |
Promethazine ADVERSE REACTIONS | confusion,disorientation, sedation, dizziness, insomnia, nervousness, Blurred vision, diplopia |
Promethazine INCOMPATABILITIES/DRUG INTERACTIONS | Potentiates other CNS depressants, Additive anticholinergic effects with other drugs possessing anticholinergic properties. |
Promethazine DOSE/ROUTE, Adult antihistamine IV | 25mg, may repeat in 2hr. |
Promethazine Adult antiemetic IV | 10-25mg Q4hr as needed. |
Promethazine Peds antihistamine IV | Not recommended |
Promethazine Peds antiemetic IV | 0.25-0.5 mg/kg q 4-6 hours |
Promethazine ONSET OF ACTION | IV 3-5 minutes |
Promethazine PEAK EFFECTS | Unknown |
Promethazine DURATION OF ACTION | 4-12 hours |
Promethazine AZ DRUG BOX SUPPLY RANGE | Not carried |