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Prochlorperazine
Question | Answer |
---|---|
Prochlorperazine GENERIC NAME | Prochlorperazine |
Prochlorperazine BRAND NAME | Compazine |
Prochlorperazine CLASS | Antiemetics, antipsychotics |
Prochlorperazine MECHANISM OF ACTION | Alters the affects of dopamine in the CNS. Possesses significant anticholinergic and alpha-adrenergic blocking activity. Diminished N/V and diminished signs and symptoms of psychoses and anxiety |
Prochlorperazine INDICATIONS | N/V, psychoses, and anxiety. |
Prochlorperazine CONTRAINDICATIONS | Narrow-angle glaucoma, severe liver or cardiovascular disease, bone marrow depression, children < 2 years. |
Prochlorperazine ADVERSE REACTIONS | extrapyramidal reactions, sedation,blurred vision, dry eyes, ECG changes, hypotension, tachycardia |
Prochlorperazine INCOMPATABILITIES/DRUG INTERACTIONS | Additive hypotension with antihypertensives, nitrates, or acute ingestion of alcohol. Additive CNS depression with other CNS depressants. |
Prochlorperazine DOSE/ROUTE Adult Antiemetic PO | 5-10mg 3-4 times daily. Up to 40 mg/daily |
Prochlorperazine DOSE/ROUTE Adult Antiemetic IV | 2.5-10mg not to exceed 40mg/daily. |
Prochlorperazine DOSE/ROUTE Adult Antipsychotic PO | 5-10mg 3-4 times daily not to exceed 150mg a day |
Prochlorperazine DOSE/ROUTE Adult Antipsychotic IV | 2.5-10mg not to exceed 40mg day |
Prochlorperazine DOSE/ROUTE Adult Antianxiety PO | 5mg 3-4 times daily not to exceed 40mg/daily |
Prochlorperazine DOSE/ROUTE Adult Antianxiety IV | 2.5-10mg not to exceed 40 mg/daily |
Prochlorperazine ONSET OF ACTION | PO 30-40minutes.IV rapid |
Prochlorperazine PEAK EFFECTS | Unknown |
Prochlorperazine DURATION OF ACTION | 3-4 hours |
Prochlorperazine AZ DRUG BOX SUPPLY RANGE | Not carried |