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Adenosine
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Machanism of Action
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medic drugs 7

Adenosine

QuestionAnswer
Adenosine Adenocard
Machanism of Action Naturally occurring nucleoside that decreases conduction through the AV node and interrupts AV and SA re-entry pathways thus restoring normal sinus rhythm in patients with SVT
Indications SVT refractory to Vagal maneuvers including Wolff-Parkinson-White (WPW)
Contraindications 2nd and 3rd Degree AV heart blocks, symptomatic Bradycardia, sick sinus syndrome, hypersensitivity
Precautions Place patient in Semi-Fowler position as patients will typically develop arrhythmias at the time of conversionUse caution in patients with Asthma
Side Effects Syncope, dizziness, dyspnea, N/V, headaches, palpitations, chest pain, hypotention and dysrhythmiasSide effects are usually self-limiting due to short half-life
Interactions Patients taking caffeine or xanthines (aminophylline or theophylline) may require larger doses as these drugs antagonize adenosine. Patients on dipyridamole(Persantine) and carbamazepine (tegretol) may need smaller doses of adenosine as these drugs poten
Dosage and Route Adult: 6 mg rapid IVP followed by 10-20ml NS flush (if no conversion after 1-2 min administer) 12mg rapid IVP followed by 10-20ml NS flush (if no conversion after 1-2 min administer) Repeat 12mg rapid IVP followed by 10-20 ml NS flush
Created by: sgeraghty
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