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Question | Answer |
---|---|
Pemirolast | Alamast,Alegysal Mast cell stabilizers |
Nedocromil | Alocril Mast cell stabilizers |
Lodoxamide thromethamide | Alomide 0.1% Mast cell stabilizers |
Cromolyn sodium 4% | Crolom, Opticrom Mast cell stabilizers |
Mast cell stabilizers-indications? | Indications: Vernal,seasonal,atopic kerato/conjunctivitis |
Antazoline phosphate | Vasocon-A H1 antihistamines - first generation |
Pheniramine maleate plus naphazoline HCL (adrenergic agonist) | Naphcon-A H1 antihistamines - first generation |
H1 antihistamines - first generation | Side effects: -ocular discomfort on instillation |
Levocabastine | Livostin 0.05% H1 antihistamines - first generation |
H1 antihistamines - second generation | Indications: Allergic conjunctivitis |
Olopatadine | (Patanol 0.1%) |
Ketotifen fumarate | (Zaditor 0.025%) |
H2 receptors-tissues | Gastric parietal cells,Heart Blood vessels,Eyeblood vessels |
H1 receptors-tissues | Bronchial smoothmusc., Heart,CNS,eye |
? Antagonist=Diphenhydramine | H1 blocker(not eye drop) |
? Antagonist=Loratidine | H1 blocker(not eye drop) |
?Antagonist=Cimetidine | H2 blocker(not eye drop) |
?Antagonist=Ranitidine | H2 blocker(not eye drop) |
Which of the following ophthalmic drugs is an H-1 receptor antagonist only and is used for allergic conjunctivitis? A. Levocabastine B. Ketotifen C. Ketorolac D. Cromolyn sodium | |
Which of the following ophthalmic drugs is an H-1 receptor antagonist only and is used for allergic conjunctivitis? A. Levocabastine B. Ketotifen C. Ketorolac D. Cromolyn sodium | A. Levocabastine (Livostin) Levocabastine (Livostin) is an H-1 antagonist Ketotifen (Zaditor) is a mast cell stabilizer AND H-1 receptor antagonist Ketorolac (Acular) is an NSAID Cromolyn sodium (Crolom, Opticrom) is a mast cell stabilizer |
What percentage of patients that have sensitivity to penicillin will have cross-reactivity to cephalosporins? | About 10% of patients with penicillin allergy will cross-react, making the use of cephalosporins potentially dangerous Allergic reactions include: Itching, rash, hives, and anaphylactic reaction that can be fatal |
Echothiophate | Cholinergic agonist |
Unoprostone isopropyl | Rescula -Prostaglandin -glaucoma |
Brinzolamide | Azopt |
Carteolol | (Ocupress) |
Non-selective Timolol | (Timoptic, Betimol) |
Levobunolol | (Betagan)Non-selective |
Metipranolol | (Optipranolol)Non-selective |
Betaxolol | (Betoptic)β1-selective |
β-adrenergic antagonists MOA | decreased aqueous production (β2-adrenoceptor at the ciliary body) |
Which of the following beta-blockers would be the most effective for someone with mild bronchoconstrictive disease? A. Timolol B. Betaxolol C. Metipranolol D. Levobunolol | Betaxolol is B1-selective, a better choice in cases with pulmonary disorders Timolol, metipranolol, and levobunolol are Badrenergic receptor antagonists that are B1/B2- nonselective |
Which of the following is not a typical side effect of topical beta-adrenergic antagonists? A. Dry eye B. Corneal anesthesia C. Alopecia D. Tachycardia | D. TACHYCARDIA Topical beta blockers SE: Ocular: Corneal anesthesia, ptosis, hypotony, burning, superficial punctate keratitis, dry eye Systemic: Fatigue, psychosis, BRADYCARDIA,syncope, alopecia, nausea, impotence, altered response to hypoglycemia, a |
Direct acting cholinergic agonists-name 2 Indirect-acting (irreversible) cholinergic agonists- name 1= inhibition of cholinesterase | Pilocarpine Carbachol Echothiophate |
All of the following effects are seen when a directacting cholinergic agonist is used except: A. Miosis B. Increase in zonular tension C. Increased outflow facility D. Traction on peripheral retina | B. Increase in zonular tension Direct-acting cholinergics include: Pilocarpine,acetylcholine, and carbachol Direct-acting cholinergics cause: Contraction of the iris sphincter, contraction of the circular fibres of the ciliary muscle with RELAXATION of |
Glaucoma-Adrenergic α-2 agonists moa | Mechanism: α2 stimulation at the ciliary body inhibits norepinephrine release, leading to decrease aqueous production |
Glaucoma-Adrenergic α-2 agonists side effects and RxRx | Side effects: conjunctival blanching, eyelid retraction, mydriasis, allergy, dry mouth, headache, potentiate MAO inhibitors |
Apraclonidine | Iopidine -Glaucoma-Adrenergic α-2 agonists |
Brimonidine | (Alphagan)-Glaucoma-Adrenergic α-2 agonists |
All of the following side effects may be seen when using apraclonidine except: A. Dry mouth B. Lid drooping C. Conjunctival blanching D. Lethargy | B. Lid drooping Apraclonidine is an A2-adrenergic agonist Side effects of Apraclonidine include: LID RETRACTION, dry mouth, lethargy, conjunctival blanching, and local allergy |
All of the following effects may be seen with the use of dorzolamide except: A. Metallic taste B. Tingling in the hands and feet C. Skin rash D. Optic neuritis | D. OPTIC NEURITIS Side effects of Dorzolamide include: Numbness in the hands, feet, or lips, a metallic taste to carbonated beverages, malaise, anorexia, weight loss, nausea, somnolence, depression, & local skin allergy |