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Cardio Drugs
Question | Answer |
---|---|
ADR of ACE inhibitors [CHF drugs] [vasodilator] | dry irritating cough because of bradykinin |
Angiotensin Receptor Blockers (ARBs) gives no cough because [CHF drugs] [vasodilator] | no bradykinin effect |
ADR of quinidine [anti-arrhythmia drugs] [Na+ block] | Torsades du Pointes, cinchonism (constipation/diarrhea, tinnitus) |
ADR of Amiodarone [anti-arrhytmia drugs] [K+ block] | smurf skin, thyroid dysfunction |
Lidocaine is DOC for [anti-arrhytmia drugs] [Na+ block] | post-MI |
ADR of Verapamil [anti-arrhytmia drugs] [Ca+ block] | AV block |
Adenosine is DOC for [anti-arrhytmia drugs] [unclassified] | PSVT and AV nodal arrhythmias |
Nitrates decrease pre-load by ______ and has an ADR of ______ [angina drugs] | dilating veins; flushing and postural HTN |
Nitroglycerine is DOC for [angina drugs] | acute angina |
Verapamil is contraindicated in [angina drugs] [Ca+ block] | patient with CHF or AV block |
What does Niacin do, and what is it's ADR? [anti-hyperlipidemic drugs] | decreases LDL, increases HDL, causes gout |
Fibrates (have fibr in name) mixed with statins cause what? [anti-hyperlipidemic drugs] | myopathy |
What does Propanolol do, and what is it's contraindications? [anti-hypertensive drugs] [adrenergic antagonist] | reflex peripheral vasoconstriction; CI in prinzmetal angina, asthma, COPD, diabetics |
Methyldopa is the DOC for ________ [anti-hypertensive drugs] [adrenergic agonists] | hypertension in pregnancy |
What should you not prescribe with Verapamil? [anti-hypertensive drugs] [Ca+ block] | beta-blockers, it causes cardiac arrest |
What does Nitroprusside do? [anti-hypertensive drugs] [direct-acting vasodilator] | vasodilates arteries and veins by releasing NO and cyanide ions, DOC for hypertensive emergency |
Carbonic anhydrase inhibitors can be used for ______ and their MOA is _______ [anti-hypertensive drugs] [diuretics] | Acute mountain sickness prophylaxis; inhibits Na-H antiport |
What are loop diuretics (sulfonamides/Furosemide) the DOC for, and what is their MOA? [anti-hypertensive drugs] [diuretics] | Acute pulmonary edema in heart failure patients; inhibits Na/K/2Cl transport |
ADR of Furosemide [anti-hypertensive drugs] [diuretics] | hypocalcemia, ototoxicity |
ADR of Spironolactine and its MOA [anti-hypertensive drugs] [K+ sparing diuretics] | anti-androgen effects, peptic ulcer; aldosterone antagonist |