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Pharm

Drug overdoses and Tx

MedicationAntagonist
ASA Sodium Bicarb (to alkalize urine)
Alcohol, Wernicke-Korsakoff Syndrome Thiamine
Benzodiazepines Flumazenil (Romazicon)
Beta Blockers Glucagon 50 mcg/kg
Calcium channel blockers Calcium Chloride 10% 8-16 mg/kg IV, slowly
Calcium Gluconate Mag Sulfate
Coumadin (Warfarin) Vitamin K
Dystonic reactions / Extrapyramidal symptoms (EPS) Diphenahydramine
Insulin Glucose (Dextrose 50%)
Methanol / Ethylene glycol (antifreeze) Fomepizol or ethanol
Opiates Naloxone (Narcan) Adult: An initial dose of 2-4 mg IV/IN/IM/SC/ET. May repeat in 2-3 min If no response after 10 mg, then condition is probably not due to narcotic. Pedi: 0.1 mg/kg IV/IM/IO/ET/SC. May repeat with 0.1 mg/kg if no improvement is noted.
Organophosphate poisoning Atropine Adult: 0.03 mg/kg (2 mg) IV / IM, repeat q 5-10 min until atropinization occurs. Pedi: 0.05 mg/kg (max. 3 mg) IV, repeat q 5-10 min until atropinization occurs.
Potassium toxicity albuterol inhaler, insulin & glucose, Sodium Bicarb
Stimulants Benzodiazepines
TCA Sodium Bicarb
Created by: MargarejoMedic
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