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Micro 7-1
Duke PA micro
| Question | Answer |
|---|---|
| Bordetella - gram negative or positive | gram negative coccobacilli |
| Bordetella - aerobic or anaerobic? | strictly aerobic |
| How many known species of Bordetella? | 7 species |
| Which species of Bordetella is a stictly human pathogen? | B. pertussis |
| B. pertussis - etiologic agent of what? | whooping cough |
| B. pertussis - lab specimens? | care must be taken - call lab |
| What do the two other species of Bordetella cause? | milder bronchopulmonary disease |
| Virulence factors of Bordetella | protein adhesins, toxins |
| Campylobacter spp. Gram negative or positive? | comma shaped Gram negative bacillus |
| How many species of Campylobacter spp? | 16, most associated with human disease |
| Campylobacter disease? | mostly gastroenteritis, sepsis, sponatenous abortion |
| Campylobacter oxygen requirements | microaerophilic; need small amount of CO2 |
| Natural reservoirs for Campylobacter? | animals |
| Route of infection of humans with Campylobacter | ingestion of contaminated food, milk, or water; also fecal/oral route |
| Virulence factors of Campylobacter | adhesins, cytoxic enzymes, and enterotoxin but their exact roles in vivo not clearly understood |
| Most common cause of bacterial gastroenteritis in USA? | Campylobacter jejuni |
| Who is at risk for infeciton with Campylobacter jejuni? | ingestion of large numbers of organisms or those lacking in gastric acid |
| Distribution and incidence of C. jejuni in different types of weather | world wide distribution, increased incidence in warm weather |
| Treatment for C. jejuni infections | disease is usually self-limiting, but antibiotic therapy is given for severe infections |
| Capnocytophaga canimorsus gram negative or positive? | fastidious Gram negative bacillus |
| First name of Capnocytophaga canimorsus given by CDC in 1984 | dysgonic fermenter (DF) |
| Capnocytophaga canimorsus normal flora | found in respiratory tract and saliva of human (DF-1) and dogs/cats (DF-2) |
| Capnocytophage canimorsus is a common cause of what kind of infections? | human bite infections |
| How severe is infection with capnocytophaga canimorsus? | mild to deadly - immunosuppression increases risk - asplenic patients can have severe sepsis |
| Eikenella corrodens gram negative or positive? | small, fastidious Gram negative bacillus; corrodes agar medium |
| What does Eikenella corrodens smell like as it grows? | bleach |
| Eikenella corrodens normal flora | upper respiratory tract of humans |
| eikenella infection | implicated in bite infections; endocarditis in patients with pre-existing heart disease |
| Eikenella risk? | risk of serious complications in patients who are immunocompromised |
| Eikenella belongs to which group? | HACEK |
| What is the most diverse group of medically important, gram negative, medium-sized bacilli | Enterobacteriaceae |
| Number of genera and species of Enterobacteriaceae | >40 genera, >150 species |
| Route of infection - enterobacteriaceae | via animal reservoir, human carrier, or endogenous - many are opportunistic, nosocomial |
| As a group account for 1/3 of all septicemias and 2/3 of all UTIs | Enterobacteriaceae, but only ~20 species account for nearly all infections |
| study from slide 10 on |
Created by:
ges13
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