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Gluconeogenesis
gluconeogenesis pathway
input | enzyme | output |
---|---|---|
lactate, NAD+ | lactate dehydrogenase | pyruvate, NADH |
pyruvate, HCO3, ATP | pyruvate carboxylase | oxaloacetate, H+, ADP + Pi |
oxaloacetate, GTP | PEP carboxy kinase | PEP, GDP, CO2 |
PEP | enolase | 2-phophoglycerate |
2-phophoglycerate | phophoglycerate mutase | 3-phophoglycerate |
3-phophoglycerate, ATP | phophoglycerate kinase | 1,3-bisphosphoglycerate, ADP |
1,3-bisphosphoglycerate, NADH, H+ | GAP dehydrogenase | GAP, NAD+ |
GAP | triose phosphate aldolase | DHAP |
DHAP | fructose-bisphosphate aldolase | fructose 1,6-bisphosphate |
fructose 1,6-bisphosphate, H2O | fructose 1,6-bisphosphatase | F6P, Pi |
F6P | phosphoglucose isomerase | G6P |
G6P, H2O | glucose-6-phosphatase | glucase, Pi |