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anger, fear, anxiety, and excitement
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trauma, fever, haemorrhage, surgery, and malnutrition
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HAP2_L6B

Stressor Response

QuestionAnswer
anger, fear, anxiety, and excitement emotional stress
trauma, fever, haemorrhage, surgery, and malnutrition physical stress
stress response is initiated by the hypothalamus
short term stress The Alarm Reaction
long term stress The stage of resistance
The body needs the ability to suddenly mobilise resources (Glucose), particularly to the heart and skeletal muscles, to allow for “fight or flight Purpose of GAS
Hypothalamus projects descending axons to autonomic nuclei in the medulla oblongata that influence HR, BP, digestive activities and respiration
Hypothalamus projects descending axons to autonomic nuclei
autonomic nuclei are in the medulla oblongata
Interneuron in the spinal cord stimulates the pre-ganglionic sympathetic nerve fibres to stimulate Adrenal medulla
Adrenal medulla releases 80% epinephrine and 20% nor-epinephrine
more potent stimulator of metabolic activities (rise in glucose), bronchial dilation, and increased blood flow to skeletal muscles and the heart. Epinephrine
has a greater influence on peripheral vasoconstriction and blood pressure Norepinephrine
The action potential travels from the limbic system to the hypothalamus
new action potential is generated by the hypothalamus and sent via descending sympathetic fibre
Alarm reaction (short term stress response) causes increase in: HR, BP, RR, metabolic rate, sweating, bronchiole and pupil dilation, glucose release to blood
Alarm reaction (short term stress response) causes decrease in: digestive system activity, urine output
During the stage of Resistance or long term stress response Hypothalamus releases Corticotropin releasing hormone( CRH)
CRH acts on anterior pituatary gland
Anterior pituatary gland releases Adrenocorticotropic hormone (ACTH)
ACTH acts on adrenal cortex
adrenal cortex releases cortisol
cortisol blood levels rise, inhibiting CRH and ACTH
during cortisol release negative feedback, the hypothalmus releases CRH into hypothalamo-hypophyseal portal system
cortisol is carried by what through systemic circulation proteins like Albumin
gluconeogenesis, lipolysis, protein catabolism in all tissues bar hepatocytes and inhibits lipogenesis in fat tissue cortisol effects
stimulates the liver to break down fats, encourages glycogen breakdown, acts as glucose sparing hormone growth hormone
stimulates metabolism and increase in glucose blood levels thyroid hormones
Na & H2O retention, dcrs in cap perm. formation of prostaglandins/leukotrines, stab. lysosomal membr. inhibits phagocytosis & suppresses T-Lymphocytes, inhibits connective tissue repair long term cortisol effects
nervous tic, fatigue, depression, anxiety, overreating, insomnia, HTN, CAD, IBS, sexual dysfunction, hair loss, autoimmune disease, tension headach State of exhaustion
Created by: 1092422624234171
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