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Path: Env
common factors
Question | Answer |
---|---|
Risk Assesment is based on? | 1) Hazard ID 2) Dose response 3) exposure assesment 4) Risk characterization |
when a patient asks am I at risk have these in mind | 1) existance of hazard 2) exposure 3) level of risk |
EPAs basis for hazardous nature | 1) no level at which it is not hazardous, 2) benign tumor - malignant tumor 3) animals are fine models |
signs of tobacco in adultes | 1) rhinitis/pharyngitis 2) conjunctival irritation 3) headache 4) wheezing 5) exacerbation of chronic resp conditions |
signs of tobacco in kids | asthma, URTI, Otitis media, snoring, pneumonia and bronchitis |
effects on the lungs of children exposed to tobacco | reduced growth and function with doubled incidence of infection and pneumonia |
when is maternal smoking damage most pronounced | 20-36 weeks |
what are some fetal dev side effects of smoking in the maternal pregnancy | abruptio placenta, placenta previa, premature rupture of the membrane |
when does tobacco exposure increase the risk of SIDS | in utero and post natal (lactation too) |
what are some volatile organic compounda | formaldehyde, benzene, pesticides, solvents cleaning agents |
key signs of volatile exposure | Eyes, Nose, Throat irritation, Headache, Allergic skin rx, Dyspnea, decreased serum cholinesterase, Nausea emesis, epistaxis (nose bleed) fatique dizzines |
how do you diagnose volatile exposure | new anything, cleaners, remodeling, others complaining |
what are the four types of radiation | alpha, Beta, gamma, X-ray |
what is the radiation that is stopped by lead adn concrete but passes through organic matter | gamma and x |
what are sources of natural radiaiton | sun and cosmic rays as well as uranium potassium radon |
why do we worry about radiation | stochastic (cancer especially kids who have more dividing cells) and non-stochastic such as radiation sickness that includes damage to bone marrow, destruction of intestinal lining adn damage to the CNS |
which radiation can we inhale and ingest | alpha and beta |
gamma does the most damage but you can be burned by? | B particles |
most heavy metals that are hazardous are | 25% ARE heavy metals number 123 aresenic, lead, mercury |
cadmium and chromium (6) are what level on the toxin scale | 7 and 16 |
mercury exposure always has? | tremor |
cadmium hurts | kidneys and bone |
chromium hurts | nasal and skin ulcers with incresaed risk of leukemia |
aluminum | linked to alzheimers may result in anemia and osteodystrophy |
Iron | hepatotoxin that causes vasodepression can occur up to 6 weeks after exposue |
too much zinc | cramps nausea vomiting and lower HDL |
lead | can cause reversal of dev. in kids |
treat lead poisoning | with chelators that make compound that drive lead out of the body |
two types of asbestos fibers | serpentine and amphiboles |
what are serpentine fibers like | small and DOES NOT DEPOSIT |
90% of the worlds asbestos is | serpentine |
what is amphiboles asbestos | long slender very brittle which makes them be trapped in the lungs |
what diseases are associated with asbestos | asbestosis, mesothelioma and lung cancer (increased in those who smoke) |
what is the acceptible level of lead in children | less than 10 ug/DL (adults are 25) |
how do you diagnose lead toxicity | whle blood level vs. whole body burden (just the blood) |
Lead poisoning in children can present as? | anorexic constipation and altering between hyperactivity and lethargy |
Chornic exposure to lead results in | peripheral neuropathy and anemia |
what effect do new pesticides (organophasphate and carbamates have on the body | bind to ach esterase so that there is no breakdown of Ach resulting in unopposed Ach stim |
acute symptoms of new pesticide inhalation | think all things autonomic |
when should pesticide exposure make you think life threatening | LOC, Incontinence, Seizures, Resp. Depression |
Treat pesticide exposrue | oxygen and atropine |
pyrethroids | mimix organophasphate toxicity but mostly act at CNS with seizures, disturbed consciousness adn paresthesia |
how do you treat pyethroid exposure | vit e? stop paresthesia |
Who is hazardous to the lungs | asbestos |
who is hazardous to the kidneys | chromium and cadmium |
who is hazardous to the hematopoietic cells | arsensic, aluminum, lead |
who is hazardous to the liver | iron and inorganic mergury |
who is hazardous to the CNS | elemental and organic mercury as well as arsenic and lead |