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SCI 221
A & P
Question | Answer |
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Homeostasis | the relatively constant states maintained by the body |
Integumentary | separates internal environment from external environment, providing stability of internal fluid volume |
Skeletal | supports and protects internal environment, allowing movement; stores minerals that can be moved into and out of internal fluid |
Muscular | powers and directs movements; provides heat |
Nervous | regulates homeostatic mechanisms, sensing changes, integrating information, sending signals to effectors |
Endocrine | regulates homeostasis by secreting signaling hormones that travel through internal environment to effector cells |
Cardiovascular | maintains internal constancy by transporting nutrients, water, oxygen, hormones, wastes, and other materials and heat within the internal environment |
Lymphatic | maintains constant fluid pressure by draining excess fluid from tissues, cleaning it, and recycling it to bloodstream |
Immune | defends internal environment against harmful agents |
Respiratory | maintains stable O2 and CO2 levels in body by exchanging these gases between external and internal environments; provides vocal communication with others for protection, hunting, etc. |
Digestive | maintains relatively constant nutrient level in body by digesting food and absorbing nutrients into internal environment |
Urinary | maintains constantly low level of waste and regulates pH of internal environment; helps maintain constancy of internal water volume and balance of ions and other substances |
Reproductive | passes genetic code containing information for forming a body and maintaining homeostasis to offspring |
There is a minimum of four basic components in every feedback control loop | 1. Sensor mechanism 2. Integrator or control center 3. Effector mechanism 4. Feedback |
Sensor | any agent or mechanism that detects a change in conditions (or stimulus) inside or outside the body, such as a sensory receptor |
Integrator | an integration center or control center that receives sensed information and compares that to stored or setpoint information, possibly sending a response to an effector that will act to change the value of the sensed information |
Effectors | organ, gland, or muscle that responds to a regulatory control signal, such as a nerve stimulus or hormone |
Negative feedback | feedback control system in which the level of a variable is changed in the direction opposite to that of the initial stimulus |
Positive feedback | feedback control system that is stimulatory; tends to amplify or reinforce a change in the internal environment |
Feed-forward | concept that information may flow ahead to another process to trigger a change in anticipation of an event that will follow |
Intracellular control | level of homeostatic control of body processes that occurs within cells, as in genetic regulation or enzymatic regulation of the cell |
Intrinsic control | level of homeostatic control of body processes that occurs within a particular tissue or organ, as when local regulators such as prostaglandins regulate local physiology |
Extrinsic control | style of physiological regulation in which the control center (regulatory center) is outside, or extrinsic to, the tissue being regulated; for example, the brain’s control of a leg muscle or the pituitary gland’s regulation of the thyroid gland |
Epidemiology | study of the occurrence, distribution, and transmission of diseases in human populations |
Idiopathic | refers to a disease of undetermined cause |
Prions | short for “proteinaceous infectious particles,” which are proteins that convert proteins of the cell into different proteins and the altered form of the protein may then be inherited; may act as a pathogen, forming abnormal protein tangles in brain cells |
Ions | ions can be positively or negaitively charged and that ions with opposite charges are attracted to each other |
Signal transduction | process of changing a signal such as a hormone or neurotransmitter into another form such as enzymatic reaction within the cell receiving the signal |
Hydrogen bonds | hydrogen bonds are much weaker forces than ionic or covalent bonds they require less energy to break. hydrogen bonds result from unequal charge distribution on a molecule |
Chromatin | threadlike form of DNA, making up the genetic material in the nucleus |
Microfilaments | smallest cell fibers |
Three basic types of chemical reactions | 1. Synthesis reactions 2. Decomposition reactions 3. Exchange reaction |
Synthesis reactions | chemical reaction that combines two or more reactants to form a more complex structure |
Exchange reactions | chemical reaction that breaks down a compound and then synthesizes a new compound by switching portions of the molecules |
Intermediate filaments | twisted strands of protein, slightly larger than microfilaments that make up part of the cell’s internal skeleton |
Rough endoplasmic reticulum (RER) | is made up of broad, flattened sacs that extend outward from the boundary of the nucleus |
Dehydration synthesis | anabolic process by which molecules are joined to form larger molecules; often called condensation reaction because it joins molecules together into a denser mass |
Buffers | compound that combines with an acid or with a base to form a weaker acid or base, thereby lessening the change in hydrogen ion concentration that would occur without the buffer; often operates as buffer pairs |
Smooth endoplasmic reticulum (SER) | No ribosomes border the membranous wall; part of the network is usually more tubular in structure than the flattened sacs of the RER |
Endoderm | innermost layer of the primary germ layers that develops early in the first trimester of pregnancy; gives rise to digestive and urinary structures, as well as many other glands and organ parts |
Mesoderm | middle layer of the primary germ layers; gives rise to such structures as muscle, bones, and blood vessels |
Ectoderm | outermost of the primary germ layers that develops early in the first trimester of pregnancy; gives rise to the skin and the nervous system |
Proteins | large molecules formed by linkage of amino acids by peptide bonds; one of the basic building blocks of the body |
Glycoproteins | substance made of molecules that are a combined form of carbohydrate and protein |
Proteoglycans | large molecule made up of a protein strand that forms a backbone to which are attached many carbohydrate molecules |
Polysaccharides | complex sugar or starch, such as glycogen and plant starches; made up of many monosaccharides |
Three types of exocrine glands may be identified | 1. Apocrine 2. Holocrine 3. Merocrine |
Stratum basal | “base layer”; deepest layer of the epidermis; cells in this layer are able to reproduce themselves |
Friction ridges | raised underlying dermal papillae; form fingerprints |
Stratum spinosum | “spiny layer”; layer of epidermis that is rich in RNA to aid in protein synthesis required for keratin production |
Stratum granulosum | “granular layer”; layer in which the process of keratinization begins |
Stratum lucidum | “clear” layer of the epidermis, in thick skin between the stratum granulosum and the stratum corneum |
Stratum corneum | tough outer layer of the epidermis; cells are filled with keratin |
Eumelanin | type of melanin pigment that is dark brown in color |
Pheomelanin | type of melanin pigment that is reddish in color |
Diaphysis | shaft of a long bone |
Epiphyses | end of a long bone; also, the pineal body of the brain |
Articular cartilage | either of a pair of cartilages found in the supporting framework of the larynx |
Periosteum | tough, connective tissue covering the bone |
Medullary cavity | hollow area inside the diaphysis of the bone that contains yellow marrow |
Interstitial growth | cartilage growth following mitosis and secre-tion of matrix by chondrocytes; interstitial growth of epiphyseal plate results in growth in length of long bones |
Appositional growth | process by which a flat bone or cartilage grows in size by addition of bony cartilage at its surface |
Endochondral ossification | process by which bones are formed by replacement of cartilage models |
Intramembranous ossification | process by which most flat bones are formed within connective tissue membranes |
Ossification centers | bone formation centers |
Primary ossification center | where a blood vessel enters the cartilage of a developing bone at the midpoint of the diaphysis to initiate bone formation |
Secondary ossification centers | growth center located in the epiphyses of long bones |
Metaphysis | hollow area inside the diaphysis of the bone that contains yellow marrow |
Synarthroses | joint in which fibrous connective tissue joins bones and holds them together tightly; commonly called sutures |
Amphiarthroses | slightly movable joint such as the one that connects the two pubic bones |
Diarthroses | freely movable joint |
Gomphoses | fibrous joint where a process is inserted into a socket; for example, the joint between the tooth and mandible |
Syndesmoses | fibrous joint |
Synchondroses | joint characterized by the presence of hyaline cartilage between articulating bones |
Biaxial joints | skeletal articulation that has two axes of movement |
Multiaxial joints | joint that permits movement around three or more axes and in three or more planes |
Radioulnar joints | articulation of the head of the radius and the radial notch of the ulna |
Radiocarpal joints | the point of articulation where the radius distally articulates directly with the carpal bones |
Intercarpal joints | articulation between the eight carpal bones |
Carpometacarpal joints | skeletal articulation between a wrist (carpal) bone and hand (metacarpal) bone |
Interphalangeal joints | articulation that exists between the heads of the phalanges and the bases of the more distal phalanges |
Prepatellar bursitis | inflammation of the prepatellar bursa; also called “housemaid’s knee” |
Satellite cells | a type of Schwann cell (neuroglial cell) that sur-rounds the cell bodies of neurons of the peripheral nervous system |
Isotonic contraction | type of muscle contraction in which the muscle sustains the same tension or pressure and a change in the distance between two bones occurs |
Isometric contraction | level of homeostatic control of body processes that occurs within cells, as in genetic regulation or enzymatic regulation of the cell |