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RBC-HEMO WS
RBC and Hemoglobin Worksheet
Question | Answer |
---|---|
What is the function of the RBC? | Contains Hemoglobin which transports oxygen to the tissues |
What 5 physiologic factors affect the RBC count? | 1 - Age; 2 - Gender; 3 - Altitude; 4 - Body fluid; 5 - Pregnancy |
How does age affect your RBC count? | 2 years to teen count gradually increases |
How does gender affect your RBC count? | Males have a higher count |
How does altitude affect your RBC count? | Less oxygen in the air raises RBC |
How does body fluid affect your RBC count? | 1 - Dehydration causes RBC to raise (less fluid to dilute) 2 - Pregnancy – RBC goes down (Fluid retention) |
Define erythrocytosis - | RBC count above normal |
What are the three main causes of erythrocytosis? | 1 - Polycythemia vera (cancer of the tissue that produces cells) 2 - Burn pt due to dehydration 3 - COPD because of a lack of oxygen |
Define oligocythemia - | RBC count below normal |
What are the two main causes of oligocythemia? | 1 - Anemia; 2 - Leukemia (Blood has too many WBC so production of RBC is affected) |
What are normal values for the adult male RBC count? | 4.5 - 6.0 million / mm3 |
What are the normal values for the adult female RBC count? | 4.0 - 5.5 million / mm3 |
What the different ways to express 52,000,000? | A.) - 5.2 million cells/mm3; B.) - 5.2 million cells / cu.mm.; C.) - 5.2 million cells / uL; D.) - 5.2 x 10 to the 6th cells / uL; E.) 5.2 x 10 to the 12th cells / L |
What is the function of hemoglobin? | ! - Carry oxygen from the lungs to the tissues by way of diffusion; 2 - Carries 25% of the carbon dioxide from the tissues to the lungs |
What are the abbreviation for hemoglobin? | Hgb, Hb, hg |
What is electroresis? | A test that separates genetic types of hemoglobin; - All are hereditary; - All differ in the structure of the polypeptide chains; (Tells how many types & how much of each A1, A2 or F the person has) |
What are the normal adult male hemoglobin values? | 15 - 17 g/dL |
What are the normal adult female hemoglobin values? | 12 - 16 g/dL |
Which diseases cause a decrease in Hgb? | 1 - Anemia; 2 - Leukemia |
Which diseases cause an increase in Hgb? | 1 - Polycythemia vera; 2 - Burn patients; 3 - COPD |
What is the composition of hemoglobin? | Heme 4% + globin 96% |
What makes heme? | Starts with iron (Fe+2) and Protoporphyrin; - 4% of molecule |
What makes globin? | Amino acids and RNA (Ribonucleic acid); 96% of molecule; |
What is RNA (Ribonucleic acid)? | Instruction or genetic material for assembling the molecule. (RNA tells which Amino Acid assembly and in what order) |
Where is hemoglobin formed? | In developing bone marrow in about 1 week |
What is the structure of hemoglobin? | 1 - 4 Molecoles of heme (each has iron in Fe+2 [ferrous state]); 2 - 4 Polypeptide chains composed of 2 indentical pairs |
What are the three normal genetic types of hemoglobin? | 1 - A1 which is two alpha & 2 Beta; 2 - A2 which is two alpha & two Delta; 3 - F which is two alpha & two Gamma |
F or gamma & alpha are found where? | In babies under 6 months; then change to A1's |
What persent of audults are A1 or A2? | 95% |
Describe the two normal physiologic types of hemoglobin? | 1 - Oxyhemoglobin (Scarlet red arterial, oxygenated blood); 2 - Reduced hemoglobin (Blue/red hemoglobin not combined with oxygen) |
What can abnormal hemoglobin pigmets no longer do? | Cannot carry oxygen |
Name three abnormal hemoglobin pigments - | 1 - Carboxy hemoglobin; 2 - Methemoglobin; 3 - Sulfhemoglobin |
What color is the abnormal hemoglobin pigment carboxyhemoglobin? | cherry red |
What color is the abnormal hemoglobin pigment methemoglobin? | Chocolate brown |
What color is the abnormal hemoglobin pigment sulfhemoglobin? | Lavender |
How does CLIA classify the STAT-Site M Hgb meter? | Waved |
How does the STAT-Site M meter determine the Hgb result? | 1 - Blood & Reagents; 2 - Hemolyzes; 3 - Hb reacts to form brown; 4 - Amount of color produced is proportional to the concentration of Hb in the sample |
Which units are used to report a Hgb result? | g/dL |
What is the normal range for RBC's? | 4.5 - 6 million for males & 4.0 - 5.5 million for females |
What is the normal range for Hbg? | 12 - 16 g/dL for women & 15 - 17 g/dL for males |
What is the normal range for WBC? | 4,000 - 11,000 cell/mm3 |