click below
click below
Normal Size Small Size show me how
Nutrition
Surgery I
Question | Answer |
---|---|
Prevalence of malnutrition in hospitalized pts | 15-50% |
Cachexia | Loss of wt, appetite, mx atrophy, & weakness; usu signifies an underlying dz |
Kwashiorkor | acute visceral protein depletion. Usually children |
Marasmus | Simple starvation |
Body composition is divided into: | fat mass & lean body mass |
Early vs late starvation | Early: proteolysis is dominant; late: body adapts to conserve protein, fat becomes major energy source |
Fat mass: % of total body wt (TBW)? | 25-35% TBW |
Lean mass: % of total body wt (TBW)? | 40% TBW |
Lean body mass composition | 60% skeletal mx; 20% RBC & conn tissue; 20% organ tissue |
peripheral neuropathy may be due to deficiencies in: | niacin, thiamine, vitamin B6, vitamin B12 |
Primary means of measuring protein (nitrogen) balance in body: | urine urea nitrogen |
marker for significant nutritional depletion: body wt that is: | less than 90% of the usual or ideal body wt |
Percentage of total body protein contained in skeletal muscle | 60% (this is major site of protein catabolism during starvation and/or illness) |
Most widely used biochemical marker of muscle mass | 24 hr urine creatinine |
Creatinine is: | degradation product of creatine, an energy storage compound located in skeletal muscle |
Most common test to measure breakdown of protein | Urinary urea nitrogen |
Lean body mass represents: | the critical cellular mass necessary for cellular structure & function; 40% of total body weight; Depletion is severe insult & defines pt morbidity & mortality |
Skin fold thickness is a reasonable estimate of adipose caloric reserves because: | 50% total body fat is subQ; fat is lost proportionally from central stores and subcutaneous tissue |
Creatinine- height index (CHI) level that defines skeletal muscle depletion | CHI < 80% |
Serum albumin half life: | 18 - 20 d |
Normal serum albumin = | > 3.5 g/dL |
Serum prealbumin: Sensitive to: | acute changes in nutrient intake |
Basal (resting) Energy Expenditure (BEE) is calculated by using: | Harris-Benedict equation |
In pts who have sustained injuries, calculate resting energy expenditure by: | bedside indirect calorimetry to determine VO2 and VCO2 (Weir Formula) |
Catabolic Index (CI): measures: | severity of stress (CI = UUN – 0.5 (dietary nitrogen intake) + 3 g) |
Routes for delivering nutrition | Enteral. Enteral plus venous. Central venous access (eg, TPN) |
Preferred route for delivering nutrition | Enteral |
Primary fuel source for body | Carbohydrates. Metabolized as glucose, stored as glycogen (both depleted from liver/muscle stores in 24-36h of fasting, then fat & protein used) |
Essential fatty acids are: | linoleic acid and linolenic acid |
Fat metabolism yields: | fatty acids, glycerol, and ketone bodies (ketone bodies used as fuel during starvation) |
Daily protein requirement in healthy adult | 0.8 gm/kg/day (minimum 0.54 gm/kg/day). Up to 2x that in stressed pt |