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Gastrointestinal

PASS program drill notes

QuestionAnswer
What disease has a corkscrew x-ray? Esophageal spasm
What disease has an apple core x-ray? Cancer
What disease has a stacked coin x-ray? Intussusception
What disease has a thumbprint x-ray? Toxic Megacolon
What disease has an abrupt cutoff x-ray? Volvulus
What disease has a barium clumping x-ray? Celiac sprue
What disease has a bird's beak x-ray? Achalasia
What disease has a string sign x-ray? Pyloric stenosis
What diseases have solid dysphagia? Schatzki's rings, stricture, and cancer
What disease has solid and liquid dysphagia? Esophageal spasm, scleroderma, achalasia
What is Barrett's esophagus? Metaplasia, ↑Adenocarcinoma risk
What are Esophageal Varices? Vomit blood everywhere, portal HTN
What is Mallory-Weiss? Tear LES mucosa, chronic vomiters
What is Boerhaave's? Tear all layers of esophagus, left-sided pneumonia/effusion
What is Achalasia? Lost LES Auerbach's, bird's beak, Chaga's, choked on solids
What is Hirschsprung's? Lost rectum Auerbach's, no meconium passage
What is Zenker's diverticulum? Cough undigested food from above UES, halitosis
What is a Traction diverticulum? Eat big bolus => gets stuck above LES
What is Plummer-Vinson syndrome? Esophageal webs, spoon nails, Fe-deficiency anemia
What are Schatzki rings? Esophageal webs in lower esophagus
What is a TE fistula? Choke with each feeding. Cough with each feeding
What is Esophageal atresia with TE fistula? Vomit with 1st feeding, huge gastric bubble
What is Duodenal atresia? Bilous vomiting with 1st feed, double bubble, Down's syndrome
What is Pyloric Stenosis? Projectile vomiting (3-4 wk. old), RUQ olive mass
How does Choanale atresia present? Turns blue with feeding
How is Tetralogy of Fallot presentation different? Turns blue with crying
What makes Scleroderma unique? ↓LES pressure
What makes Esophageal spasms unique? ↑ peristalsis
What makes Achalasia unique? ↓Peristalsis and ↑LES pressure
What disease has RUQ olive mass? Pyloric Stenosis
What disease has an RLQ sausage mass? Intussusception
What is a Bezoar? Mass hair or vegetables ==> antrum obstruction
What is Gastritis type A? Upper GI bleed, anti-parietal cell Ab
What is Gastritis type B? Upper GI bleed, spicy foods, H. pylori infection
What is a Duodenal ulcer? Too much acid --> pain after meal/at night, type O blood, H. pylori, pain relieved by eating
Which type of GI ulcer pain is relieved by eating? Duodenal ulcer
What is a Gastric ulcer? Broken mucus layer: pain during meal, NSAIDs, type A blood
Which type of GI ulcer is most likely associated with losing weight? Gastric ulcer
What is a Sliding hiatal hernia? Fundus slides from esophageal hiatus to thorax ==> sucks acid into thorax
What is Rolling hiatal hernia? Fundus sticks thought hole in diaphragm, strangulates bowel "rolls"
What is Menetrier's disease? Protein-losing, thick stomach rugal folds
What defines constipation? < 3 BM per week
What defines diarrhea? > 200g per day
What is Osmotic diarrhea? Watery
What is Secretory diarrhea? Laxative use
What is inflammatory diarrhea? Blood, pus
What is Celiac Sprue? Jejunum, wheat allergy, villous atrophy, anti-gliadin Ab
What is the antibody associated with Celiac Sprue? Anti-gliadin antibody
What is Tropical Sprue? Ileum celiac sprue
What is Mesenteric Ischemia? Pain out of proportion during physical exam
What bugs cause bloody diarrhea? "CASES" Campylobacter Amoeba (E. histolytica) Shigella E. coli (EHEC) Salmonella
What is the difference b/w 1 Biliary Cirrhosis and 1 Sclerosing Cholangitis? PBC ==> anti-mitochondrial Ab, bile ducts destroyed, xanthelasma PSC ==> p-ANCA Ab, bile duct inflammation, beading, onion skinning, associated with UC
What is Ascending Cholangitis? Common duct stone gets infected
What are signs of alcoholic cirrhosis? Spider angioma, palmar erythema, Dupyutren's contractions
What is Hepatorenal syndrome? Pts with liver disease build up liver toxins that cause renal failure
What is Cholangitis? Inflammation of bile duct => Charcot's triad, Reynold's pentad
What is Cholecystitis? Inflammation of gallbladder ==> Murphy's sign (+)
(+) Murphy sign Cholecystitis
What is Cholelithiasis? Formation of gallstones ==> RUQ colic
What is Cholestasis? Obstruction of bile duct ==> pruritis, ↑alkaline phosphatase, jaundice
What is Conjugated bilirubin? Water soluble; "direct"
What is Unconjugated bilirubin? Fat soluble; "indirect"
What is the most common type of gallstone? Cholesterol (can't see on x-ray)
What type of gallstone can be seen on x-ray? Ca-bilirubinate
What is Xanthoma? Cholesterol buildup (elbow or Achilles)
What is Xanthelasma? Triglyceride buildup (under eye)
What does high cholesterol cause? Atherosclerosis
What does high triglycerides cause? Pancreatitis
What is Type 1 Hyperlipidemia? Bad liver LL (CM)
What is type 2a Hyperlipidemia? Bad LDL or B-100 receptors; trapped in ER (LDL only)
What is type 2b Hyperlipidemia? Less LDL/VLDL receptors (LDL/VLDL)
What is type 3 Hyperlipidemia? Bad Apo E (IDL/VLDL)
What is type 4 Hyperlipidemia? Bad Adipose LL (VLDL only)
What is type 5 Hyperlipidemia? Bad C2 (VLDL/CM) because C2 stimulates LL
What is Crigler-Najjar? Unconjugated bilirubin, usually in infants
What is Gilbert's syndrome? Glucoronyl transferase is saturated ==> stress unconjugated bilirubin
What is Rotor's? Bad bilirubin excretion => conjugated bilirubin
What is Dubin-Johnson? Bad bilirubin excretion => Black liver
What is Cullen's sign? Bleed around umbilicus ==> hemorrhagic pancreatitis
What is Turner's sign? Bleed into flank ==> hemorrhagic pancreatitis
What test is used for following pancreatitis? - Amylase --> sensitive, breaks down carbs
What does Ranson's criteria tell you? Poor prognosis for pancreatitis patients
What is Ranson's criteria at presentation? "WAGLA" WBC > 16 K/Ul (infection) Age >55 (usually multiple illness) Glucose > 150 mg/dL (islet cells are fried) LDH: > 350 IU/L (cell death) AST: >250 IU/L (cell death)
What is Ranson's criteria at 48 hours? "BuCH was a SOB" BUN: ↑ >5mg/dL (↓renal blood flow) Ca: < 8 mg/dL (saponification) Hct: drops > 10% (bleed into pancreas), Sequester > 6 L fluid => 3rd spacing pO2 <60 mm Hg (fluid/protein leak --> ARDS) Base deficit > 4mEq/L (diarrhea => pancreatic enzymes are dead)
What is Carcinoid syndrome? Diarrhea, flushing, wheezing
Which NT is associated with Carcinoid syndrome? Serotonin
What produces Currant Jelly sputum? Klebsiella
What produces Currant Jelly stool? Intussusception
What is Gardener's syndrome? Familial polyposis with bone tumors
What is Turcot's syndrome? Familial polyposis with brain tumors
What is Familial polyposis? 100% risk of colon cancer, APC defect ==> annual colonoscopy at 5 y/o
What is Peutz-Jegher syndrome? Hyperpigmented mucosa ==> dark gums,/vagina with hyperplastic polyps
What is Chron's disease? IBD with cobblestones, melena, creeping fat, fistulas
What is Ulcerative Colitis? IBD with pseudopolyps, hematochezia, lead pipe colon, toxic megacolon
Which biliary condition is often associated with UC? Primary Sclerosing Cholangitis
What is Intussusception? Currant jelly stool, staked coin appearance on enema, symptoms come and go
How does Diverticulosis present? Bleeds
How does Diverticulitis present? Hurts
Hoes dos Spastic Colon present? Intermittent severe cramps
How does IBS present? Alternating diarrhea/constipation
How do External Hemorrhoids present? Pain
How do Internal Hemorrhoids present? No pain
What is Pseudomembranous colitis? Overgrowth of C. difficile due to normal flora being killed off, usually by Clindamycin use
What is Whipple's disease? T. whippleii destroys GI tract, then spread causing malabsorption
What color is an upper GI bleed? Black
What color is a lower GI bleed? Red
What adds color to stool? Bilirubin
What is the default color of stool? Clay-colored
What is the default color of urine? Tea-colored
Created by: rakomi
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