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Antipsychotics
FA psychiatry pharm
Question | Answer |
---|---|
List of 1st generation antipsychotics: | 1. Haloperidol 2. Pimozide 3. Trifluoperazine 4. Fluphenazine 5. Thioridazine 6. Chlorpromazine |
List of 2nd generation antipsychotics: | - Aripiprazole - Asenapine - Clozapine - Olanzapine - Quetiapine - Iloperidone - Paliperidone -Risperidone, Lurasidone - Ziprasidone |
Which generation are the "atypical" antipsychotics? | Second generation |
Which receptor is blocked by 1st and 2nd generation antipsychotics? | D2 |
Which receptors are blocked by 2nd generation antipsychotics? | D2 and 5-HT2 (serotonin) |
Which atypical antipsychotic is a D2 partial agonist? | Aripriprazole |
What are the conditions of being treated with antipsychotics? | 1. Schizophrenia 2. Disorders with concomitant psychosis 3. Tourette syndrome 4. OCD 5. Huntington disease |
What antipsychotic is used in a patient with persistent suicidality? | Clozapine |
Typical antipsychotic treat negative, positive, both symptoms in Schizophrenia? | Positive symptoms |
Atypical antipsychotics treat negative, positive, or both symptoms in Schizophrenia? | Positive and Negative symptoms |
The mnemonic "anti-HAM" provides 3 adverse effects of antipsychotics? | AntiHistaminic Anti-α1 - adrenergic (orthostatic hypotension) AntiMuscarinic |
Which antipsychotic is strongly associated with increasing weight gain? | Olanzapine |
What are the significant adverse effects of Clozapine? | Agranulocytosis, Seizures, and Myocarditis |
What are the main endocrine adverse effects of antipsychotic use? | HYPERPROLACTINEMIA ----->Galactorrhea, Oligomenorrhea, and Gynecomastia |
What adverse syndrome is due to antipsychotic toxicity? | Neuroleptic Malignant syndrome |
What are the Extrapyramidal symptoms? |