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Genetics/genome
final patho
Term | Definition |
---|---|
Genomics | Study of stricture, function, and analysis of human genome |
Epigenetics | External modification of DNA |
Epigenomics | Chemical compounds that instruct where and when genes are expressed |
Genome | all humans 99.9% identical |
Genomics | study of entire genome vs disease and disorder mechanism |
Benign tumor | non-cancerous, slow growth, well defined, don't spread (non-invasive) |
Neoplasm | abnormal growth |
Apoptosis | destruction of cells |
Oncogenes | cancer causing genes |
Hyperplasia | increased cell number |
Atrophy | shrinking in cell size |
Metaplasia | cell changes form; less likely to lead to cancer |
Hypertrophy | increase in cell size |
Dysplasia | abnormal development of cells; more likely to lead to cancer |
Proto-oncogenes | normal cell genes responsible for normal growth and division |
Tumor suppressor genes | suppress tumors |
DNA repair genes | repairs DNA and errors during replication |
Caretaker genes | repairs damaged DNA |
Telomeres | protective caps on ends of chromosome (cancer removes these) |
Neovascualrization | growth of new vessels |
Tumor-associated macrohpages | key cell that promotes tumor survival |
Tumor markers | substance expressed by tumors or normal tissue in response to tumor |
Paraneoplastic syndrome | caused when a tumor marker expresses itself |
Cachexia | shivering |
Carcinoma in situ | has not spread |
Ischemia | Lack of profusion |
Infarction | Tissue death |
autosomal | Everything other than X and Y |
Hemophilia | blood disorder (clotting effect) |