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immunity
final patho
Term | Definition |
---|---|
Innate immunity | First response, nonspecific |
Examples of innate immunity | skin, pH of GI tract, tears |
When cytokinesis stimulates the immune system, thye injust bacteria/virus and undergo what? | apoptosis (cell death) |
Adaptive immunity | specific response, memory response, T and B cells |
Memory response | Develops after 2nd exposure |
Compromising lymphocytes in adaptive immunity | T & B cells |
B lymphocyte immunity | mature in bone marrow, destroys bacteria by producing antibodies & prevents them from entering host cell |
T lymphocyte immunity | Matures within thymus gland . responds directly to antigens which involve target cells like virus infected cells |
Type 1 immune disorder: immediate hypersensitivity | allergy |
Type 2 immune disorder: cytoxic hypersensitivity | Antibody-mediated, blood transfusion, protein attacks invader |
Type 3 immune disorder: immune complex hypersensitivity | immune complex, antigen-antibody |
Type 4 immune disorder: delayed hypersensitivity | t cell mediated, poison ivy, contact dermatitis |
Asthma | chronic inflammatory disorder of airways |
Risk factors of asthma | RSV, Males before puberty, Females after adolescence, exposure to allergens, smoke exposure |
Allergic classification | triggered by allergens *TYPE 1* |
Non-allergic classification | triggered by factors that don't cause true allergic reaction |
IgE | maintains persistent inflammation |
Mast cells release what? | Histamine |
s/s of asthma | recurrent chest tightness, SOB, wheezing, cough worse at night or early a.m., thick sputum, Severe: Tachypnea, Tachycardia |
How do you test for asthma? | Confirmatory test-challenge test or peak flow maneuver |
Confirmatory test-challenge test | Breathes dilute amounts of an irritating substance that provoked airway obstruction/asthma |
Peak flow maneuver | measures the max airflow through airways when the individual exhales very strongly after max inhalation |