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Endocrine

Posterior Pituitary

HORMONESTIMULATED BY (physiologic)INHIBITED BYPHYSIOLOGIC EFFECTS
Vasopressin (ADH)-Posterior Pituitary Hyperosmolality Hypovolemia Volume depletion Hypoosmolality Hypervolemia Acts on Renal collecting ducts to prevent diuresis (proper fluid balance and acts on the renal collecting ducts to conserve water) Vasoconstriction
Oxytocin- Posterior Pituitary Parturition Suckling Uterine contraction (smooth muscles) during parturition Milk ejection (lactation)
Growth Hormone (GH) (physiologic) GH-releasing hormone (GHRH) Ghrelin ADH GABA Norepinephrine Dopamine Serotonin Estrogen Sleep Stress Exercise Somatostatin Elevated insulin-like growth factor-1 (IGF-1) Growth Hormone Progesterone Glucocorticoids Postprandial hyperglycemia Elevated free fatty acids stimulates IGF-I production IGF-I and GH promote growth in all body tissues
Growth Hormone (GH) (Pharmacologic) a-adrenergic agonist b-adrenergic ANTAgonists Dopamine agonists GABA agonists a-adrenergic antagonists b-adrenergic agonists Dopamine antagonist Serotonin antagonist stimulates IGF-I production IGF-I and GH promote growth in all body tissues
Prolactin- Physiologic Thyrotropin- releasing hormone (TRH) Vasoactive intestinal peptide (VIP) Estrogen Serotonin Histamine Endogenous opioids Pregnancy and nursing Dopamine (hypothalamic release of dopamine) (prolactin inhibitory hormone) inhibits the secretion of prolactin GABA Lactation
Prolactin- Pharmacologic Dopamine antagonists Opiates Estrogen H2-antagonists Monoamine Oxidase (MAO) inhibitors Dopamine agonists
Adrenocorticotropic Hormone (ACTH) physiologic/ pharmalogic Corticotropin-releasing hormone (CRH) Elevated cortisol Dopamine agonists (pharmacologic) Somatostatin analogs (pharmacologic) Glucocorticoid effects Mineralocorticoid effects Androgen (testosterone and estradiol) effects
Thyroid-stimulating Hormone (TSH) Thyrotropin- releasing hormone (TRH) Estrogens Norepinephrine Serotonin Thyroxine (T4) Triiodothyronine (T3) Somatostatin Glucocorticoids Dopamine Iodine uptake and thyroid hormone synthesis
Luteinizing Hormone (LH) Gonadotropin-releasing hormone (GnRH) (pulsatile) Clomiphene (pharmacologic) Fasting Estrogen Inhibin Testosterone GnRH (tonic, leuprolide) Ovulation Maintains corpus luteum Stimulates testosterone production
Follicle-Stimulating Hormone (FSH) GnRH (pulsatile) Menopause Ovarian disorders Clomiphene Fasting Estradiol Inhibin GnRH (tonic, leuprolide) Ovarian follicle development Stimulates estradiol and progesterone Spermatogenesis
Created by: vinhthaihoa
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