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NURS 319: Cell

Chapters 1 & 2: Cellular Regulation and Cancer

QuestionAnswer
Etiology cause or causes of disease
homeostasis maintaining balance in the body; regulation
allostasis the process of returning to the state of homeostasis
cellular adaptation cell accustoms to disruptions in the environment
pathogenesis beginning of abnormality
histology study of tissues
biopsy portion of cells examined to determine if they're benign or malignant
function of cells support body/ organs by providing oxygen/ nutrients to the body
What key glycoproteins are found on the cell membrane that serve as markers that allow the cell to be recognized as a part of the body or foreign? antigens
What is the main purpose of the sodium-potassium pump in the cell? to balance fluid going in and out of the cell; keep sodium potassium ratio balanced
Are mitochondrial diseases linked to the mother or father? mother
What are the two types of cellular respiration? Where does it occur in the cell? Anaerobic metabolism- no oxygen, output 2 atp and lactic acid Aerobic metabolism- oxygen, output 34 atp
What are the key molecules needed for cellular respiration to occur? glucose and oxygen
What are the nitrogenous wastes from aerobic and anaerobic metabolism? aerobic: carbon dioxide anaerobic: lactic acid
The process of a cell changing from a simple form to a more specialized cell is called ___________. An example of this is a cell going from a _______ cell which is the most basic cell to a mature lung cell. differentiation; stem
______ is the term for shrinking cells. This can occur from a decrease in work demands. atrophy
_______ is the term for enlarging cells. This occurs from excessive use. It can be physiologic enlargement which is ______ or ______ which is abnormal. hypertrophy; normal or pathologic
Once a stimulus is removed, cells can go back to normal. What is an example of this? lifting weights to gain muscle; stop lifting weights, lose muscle
Metaplasia is a _______ change where one cell type is replaced by another in response to chronic irritation. What is an example of this? physiological; stomach cells migrating to esophagus due to GI damage
________ is characterized by deranged cell growth of specific tissue resulting in cells that very in size, shape, and organization. It can be corrected if the irritant is removed. What is an example of this? Dysplasia; cervix pre and post natal cervix
________ is new growth and like anaplasia are cancerous cells. Neoplasis
What is the difference between benign and malignant? Benign is slow-growing, well-defined borders, similar to cells in area, localized Malignant is fast-growing, irregular shape- no borders, look nothing like cells in area, travel to other areas
______ is abnormal cells that remain localized. Benign
_______ cells spread to other areas. Malignant
What are some things that lead to cell injury? Hypoxia, free radical injury, defects in protein synthesis
Where do you find endothelium? interior of vessels
What does VEGF do? collateral blood flow
What does nitric oxide do? secretes when vessels are constricted
Define angiogenesis produces own blood supply
_______ is programmed cell death. This can be helpful or harmful. How can it be helpful? How can it be harmful? Apoptosis Helpful: gets rid of unnecessary cells Harmful: occurring too much/ too little
What is infarction? What causes it? What happens to muscle tissue if oxygenated blood flow is not returned to it? Irreversible lack of blood flow/ blockage buildups muscle stops working properly
Describe necrosis. What causes it? death of tissue lack of blood flow
______ occurs from bacteria that grow in the dead tissue. There are two types, give an example of each. Gangrene wet gangrene: diabetic foot ulcer (ooze, smell) dry gangrene: untreated frostbite (turns black)
Created by: lcorlew1
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