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NURS 319: Cell
Chapters 1 & 2: Cellular Regulation and Cancer
Question | Answer |
---|---|
Etiology | cause or causes of disease |
homeostasis | maintaining balance in the body; regulation |
allostasis | the process of returning to the state of homeostasis |
cellular adaptation | cell accustoms to disruptions in the environment |
pathogenesis | beginning of abnormality |
histology | study of tissues |
biopsy | portion of cells examined to determine if they're benign or malignant |
function of cells | support body/ organs by providing oxygen/ nutrients to the body |
What key glycoproteins are found on the cell membrane that serve as markers that allow the cell to be recognized as a part of the body or foreign? | antigens |
What is the main purpose of the sodium-potassium pump in the cell? | to balance fluid going in and out of the cell; keep sodium potassium ratio balanced |
Are mitochondrial diseases linked to the mother or father? | mother |
What are the two types of cellular respiration? Where does it occur in the cell? | Anaerobic metabolism- no oxygen, output 2 atp and lactic acid Aerobic metabolism- oxygen, output 34 atp |
What are the key molecules needed for cellular respiration to occur? | glucose and oxygen |
What are the nitrogenous wastes from aerobic and anaerobic metabolism? | aerobic: carbon dioxide anaerobic: lactic acid |
The process of a cell changing from a simple form to a more specialized cell is called ___________. An example of this is a cell going from a _______ cell which is the most basic cell to a mature lung cell. | differentiation; stem |
______ is the term for shrinking cells. This can occur from a decrease in work demands. | atrophy |
_______ is the term for enlarging cells. This occurs from excessive use. It can be physiologic enlargement which is ______ or ______ which is abnormal. | hypertrophy; normal or pathologic |
Once a stimulus is removed, cells can go back to normal. What is an example of this? | lifting weights to gain muscle; stop lifting weights, lose muscle |
Metaplasia is a _______ change where one cell type is replaced by another in response to chronic irritation. What is an example of this? | physiological; stomach cells migrating to esophagus due to GI damage |
________ is characterized by deranged cell growth of specific tissue resulting in cells that very in size, shape, and organization. It can be corrected if the irritant is removed. What is an example of this? | Dysplasia; cervix pre and post natal cervix |
________ is new growth and like anaplasia are cancerous cells. | Neoplasis |
What is the difference between benign and malignant? | Benign is slow-growing, well-defined borders, similar to cells in area, localized Malignant is fast-growing, irregular shape- no borders, look nothing like cells in area, travel to other areas |
______ is abnormal cells that remain localized. | Benign |
_______ cells spread to other areas. | Malignant |
What are some things that lead to cell injury? | Hypoxia, free radical injury, defects in protein synthesis |
Where do you find endothelium? | interior of vessels |
What does VEGF do? | collateral blood flow |
What does nitric oxide do? | secretes when vessels are constricted |
Define angiogenesis | produces own blood supply |
_______ is programmed cell death. This can be helpful or harmful. How can it be helpful? How can it be harmful? | Apoptosis Helpful: gets rid of unnecessary cells Harmful: occurring too much/ too little |
What is infarction? What causes it? What happens to muscle tissue if oxygenated blood flow is not returned to it? | Irreversible lack of blood flow/ blockage buildups muscle stops working properly |
Describe necrosis. What causes it? | death of tissue lack of blood flow |
______ occurs from bacteria that grow in the dead tissue. There are two types, give an example of each. | Gangrene wet gangrene: diabetic foot ulcer (ooze, smell) dry gangrene: untreated frostbite (turns black) |