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Infectious Diseases
Stage 1 Biology S2
Term | Definition |
---|---|
non infectious diseases | a disease that cannot be transmitted from one organism to another |
causes for non infectious diseases | carcinogens, radiation, faulty genes, organ and tissue degeneration, sensitivity to the environment |
pathogens | disease causing agents |
toxins | chemicals that disrupt normal cell functions |
physical barriers | respiratory surfaces, wounds digestive system, reproductive organs |
vector | a carrier of a disease causing agent |
vector example | mosquitoes, fleas, bats, flies |
producing toxins | an adaptation used by many microbes |
altering host organism behaviour | aiding in the spread of disease by making hosts cough, sneeze or have diarrhea |
superbugs | new strains of bacteria that are resistant to all known antibiotics |
infectious disease | a disease that is transmitted from one organism to another |
bacteria | unicellular, prokaryotic organisms that reproduce by binary fission |
bacteria examples | lyme disease, tuberculosis, leprosy, salmonella |
fungi | heterotrophs that grow by feeding on organic matter and reproduce by forming spores |
fungi examples | athletes foot and ringworm |
pathogenic protists | heterotrophs that absorb nutrients from their host |
pathogenic protsists examples | malaria and giardia |
virus | requires another organisms cells to reproduce by injecting its own DNA and replicating it inside the cell |
virus examples | COVID, HIV and influenza |
parasites | live inside hosts, feeding on its hosts food in the intestines. |
parasite examples | tape worm, hookworm, lice, fleas |
prions | infectious agents that convert normal proteins into abnormally chaped proteins, causing infectious brain leisions |
prion example | Mad cow disease |
disease transmission | droplets, direct contact, faeces, contaminated foods, animals, body fluids |
first line of defence | physical barriers and traps that resist and prevent entry of pathogens |
second line of defence | non specific actions and responses |
third line of defence | adaptive immune response |
skin | provides a barrier, repels water, platets form scabs |
coughing and sneezing reflexis | brought about by either mechanical or chemical stimuli |
mechanical protection | blinking, the cornea, tears all making it harder for pathogens to enter |
chemical protection | the cells in the eye secrete a range of chemicals that possess antimicrobial properties |
earwax | a mixture of a range of chemicals that are antimicrobial |
mucus | a slippery secretion found on the surface of many body organs and systems |
stomach acid | The cells lining the stomach secrete acid giving the stomach environment a very low pH |
non self molecules | foreign molecules |
self molecules | the bodys own molecules |
phagocytes | white blood cells recognise and bind to the surface of bacteria and engulf and destroy them |
2 types of phagocytes | neutrophils and macrophages |
natural killer cells | provides protection against cells infected with virus particles or changed by cancer |
the complement system | a group of around 30 proteins that are secreted by a range of cells in the body |
interferons | chemicals that can be secreted by cells that limit the spread and multiplication of viruses |
the inflammatory response | swelling, redness, pain, and heat at wound sites, triggered by physical injury or pathogen entry |
plant physcial barriers | waxy cuticles, bark, hair like sturctures |
the lymphatic system | a network of vessels, nodes, and ducts that collect and circulate excess fluid in the body |
Major Histo-compatability Complex | a set of protein markers found on the surface of cells |
lymphocytes | types of white blood cells called B and T cells |
B cell location | white blood cells that are made and mature in the bone marrow |
T cell location | mature in the thymus gland |
macrophages | release chemicals, cytokines, that alert other cells to the presence of pathogens |
B cell function | white blood cells that release a specific antibody which is a protein molecule that can bind to one specific antigen and neutralise it |
plasma cells | release antibodies |
memory cells | remain behind in the case of a second exposure to the anitgen or pathogen |
T cell function | bind to antigen fragments and T cell receptors on the cell membrane |
types of T cells | killer, helper and memory T cells |
killer T cells | identify infected cells and secrete chemicals that destroy them |
helper T cells | become activated and increase in number (clone) the types of T cells that respond to the specific antigen type |
memory T cells | this memory bank of cells is partly responsible for the quicker and larger response when an individual is exposed to the antigen for a second time |
natural passive immunity | maternal antibodies through the placenta and breastmilk |
phagocytes vs lymphocytes | phagocytes are the body's first line of defense, lymphocytes are more specialized in the immune response |
artificial passive immunity | an infusion of antibodies |
natural active immunity | antigens from the exposure to a pathogen |
artificial active immunity | antigens from vaccination |
cytotoxic T cell | another name for killer T cells |
pandemic | a worldwide spread of a pathogen |
epidemic | a spread of a pathogen in a certain region over a certain period of time |