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Infectious Diseases

Stage 1 Biology S2

TermDefinition
non infectious diseases a disease that cannot be transmitted from one organism to another
causes for non infectious diseases carcinogens, radiation, faulty genes, organ and tissue degeneration, sensitivity to the environment
pathogens disease causing agents
toxins chemicals that disrupt normal cell functions
physical barriers respiratory surfaces, wounds digestive system, reproductive organs
vector a carrier of a disease causing agent
vector example mosquitoes, fleas, bats, flies
producing toxins an adaptation used by many microbes
altering host organism behaviour aiding in the spread of disease by making hosts cough, sneeze or have diarrhea
superbugs new strains of bacteria that are resistant to all known antibiotics
infectious disease a disease that is transmitted from one organism to another
bacteria unicellular, prokaryotic organisms that reproduce by binary fission
bacteria examples lyme disease, tuberculosis, leprosy, salmonella
fungi heterotrophs that grow by feeding on organic matter and reproduce by forming spores
fungi examples athletes foot and ringworm
pathogenic protists heterotrophs that absorb nutrients from their host
pathogenic protsists examples malaria and giardia
virus requires another organisms cells to reproduce by injecting its own DNA and replicating it inside the cell
virus examples COVID, HIV and influenza
parasites live inside hosts, feeding on its hosts food in the intestines.
parasite examples tape worm, hookworm, lice, fleas
prions infectious agents that convert normal proteins into abnormally chaped proteins, causing infectious brain leisions
prion example Mad cow disease
disease transmission droplets, direct contact, faeces, contaminated foods, animals, body fluids
first line of defence physical barriers and traps that resist and prevent entry of pathogens
second line of defence non specific actions and responses
third line of defence adaptive immune response
skin provides a barrier, repels water, platets form scabs
coughing and sneezing reflexis brought about by either mechanical or chemical stimuli
mechanical protection blinking, the cornea, tears all making it harder for pathogens to enter
chemical protection the cells in the eye secrete a range of chemicals that possess antimicrobial properties
earwax a mixture of a range of chemicals that are antimicrobial
mucus a slippery secretion found on the surface of many body organs and systems
stomach acid The cells lining the stomach secrete acid giving the stomach environment a very low pH
non self molecules foreign molecules
self molecules the bodys own molecules
phagocytes white blood cells recognise and bind to the surface of bacteria and engulf and destroy them
2 types of phagocytes neutrophils and macrophages
natural killer cells provides protection against cells infected with virus particles or changed by cancer
the complement system a group of around 30 proteins that are secreted by a range of cells in the body
interferons chemicals that can be secreted by cells that limit the spread and multiplication of viruses
the inflammatory response swelling, redness, pain, and heat at wound sites, triggered by physical injury or pathogen entry
plant physcial barriers waxy cuticles, bark, hair like sturctures
the lymphatic system a network of vessels, nodes, and ducts that collect and circulate excess fluid in the body
Major Histo-compatability Complex a set of protein markers found on the surface of cells
lymphocytes types of white blood cells called B and T cells
B cell location white blood cells that are made and mature in the bone marrow
T cell location mature in the thymus gland
macrophages release chemicals, cytokines, that alert other cells to the presence of pathogens
B cell function white blood cells that release a specific antibody which is a protein molecule that can bind to one specific antigen and neutralise it
plasma cells release antibodies
memory cells remain behind in the case of a second exposure to the anitgen or pathogen
T cell function bind to antigen fragments and T cell receptors on the cell membrane
types of T cells killer, helper and memory T cells
killer T cells identify infected cells and secrete chemicals that destroy them
helper T cells become activated and increase in number (clone) the types of T cells that respond to the specific antigen type
memory T cells this memory bank of cells is partly responsible for the quicker and larger response when an individual is exposed to the antigen for a second time
natural passive immunity maternal antibodies through the placenta and breastmilk
phagocytes vs lymphocytes phagocytes are the body's first line of defense, lymphocytes are more specialized in the immune response
artificial passive immunity an infusion of antibodies
natural active immunity antigens from the exposure to a pathogen
artificial active immunity antigens from vaccination
cytotoxic T cell another name for killer T cells
pandemic a worldwide spread of a pathogen
epidemic a spread of a pathogen in a certain region over a certain period of time
Created by: justineforrest
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