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HYImmunosuppressants
DIT Day 13.3
Question | Answer |
---|---|
Which immunosuppressant matches the following statement?: used as a sedative during pregnancy until it was discovered that it caused phocomelia (flipper limbs) in infants. | thalidomide |
Which immunosuppressant matches the following statement?: binds FDBP-12 intracellular protein to inhibit mTOR which inhibits T cell proliferation | sirolimus |
Which immunosuppressant matches the following statement?: precursor of 6-mercaptopurine | azathioprine |
Which immunosuppressant matches the following statement?: may prevent nephrotoxicity with mannitol diuresis | cyclosporine |
Which immunosuppressant matches the following statement?: antibody that binds to CD3 on T cells | muromonab |
Which immunosuppressant matches the following statement?: antibody that binds IL-2 receptor on activated T cells | daclizumab |
Which immunosuppressant matches the following statement?: inhibits ionosine monophosphate dehydrogenase | mycophenolate |
Which immunosuppressant matches the following statement?: inhibits calcineurin--> loss of IL-2 production --> blockage of T cell differentiation and activation | cyclosporine |
Which immunosuppressant matches the following statement?: binds FK-binding protein--> loss of IL-2 production | tacrolimus |
Which immunosuppressant matches the following statement?: used for lupus nephritis | mycophenolate |
Which immunosuppressant matches the following statement?: metabolized by xanthine oxidase so allopurinol increases its toxicity | azathioprine |