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HII Presentations
Rapid-rev presentations relevant to HII unit
Question | Answer |
---|---|
Adrenal hemorrhage, Hypotension, DIC | Waterhouse-Friderichsen syndrome (meningococcemia) |
Back pain, fever, night sweats, weight loss | Pott’s disease (vertebral tuberculosis) |
Bluish line on gingiva | Burton’s line (lead poisoning) |
Child with fever develops red rash on face that spreads to body | “slapped cheeks” (erythema infectiosum/fifth disease: parvovirus B19) |
Dark purple skin/mouth nodules | Kaposi’s sarcoma (usually AIDS patients) [associated with HHV-8) |
Dog or cat bite resulting in infection | Pasteurella multocida |
Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells | Sezary syndrome (cutaneous T-cell lymphoma) or mycosis fungoides |
Fever, chills, headache, myalgia following antibiotic treatment for syphallis | Jarisch-Herxheimer reaction (rapid lysis of spirochetes results in toxin release) |
Fever, cough, conjunctivitis, coryza, diffuse rash | Measles (morbillivirus) |
Fever, night sweats, weight loss | B-cell symptoms (lymphomas) |
Indurated, ulcerated genital lesions (nonpainful) | chancre (primary syphilis) |
Large rash with bull’s eye appearance | erythema chronicum migrans from tick bite (Lyme disease: Borrelia burgdorferi) |
Male child, recurrent infections, no mature B cells | Bruton’s disease (X-linked agammaglobulinemia) |
Painful blue fingers/toes, hemolytic anemia | cold agglutinin disease (autoimmune hemolytic anemia caused by Mycoplasma pneumonia or EBV (infectious mononucleosis)) |
Palpable purpura, joint pain, abdominal pain (child) | Henoch-Schonlein purpura (IgA vasculitis affecting skin and kidneys) |
Pupil accommodates but doesn’t react | Argyll-Robertson (prostitute’s) pupil (neurosyphilis) |
Rash on palms and soles | 2ary Syphilis, Rocky Mountain spotted fever |
Red “currant jelly” sputum | Klebsiella pneumonia |
Red urine in the morning | paroxysmal nocturnal hemoglobinuria |
Renal cell carcinoma, hemangioblastomas, angiomatosis, pheochromocytoma | von Hippel-Lindau disease (dominant tumor suppressor gene mutation—VHL gene on short arm of 3rd chromosome (3p26–p25)). |
Retinal hemorrhages with pale centers | Roth’s spots (bacterial endocarditis) |
Short stature, ↑ incidence of tumors/leukemia, aplastic anemia | Fanconi’s anemia (genetic) |
Small irregular red spots on buccal/lingual mucosa with blue-white centers | Koplik spots (measles) |
Small, nontender, erythematous lesions on palms/soles | Janeway lesions (infective endocarditits) |
Smooth, flat, moist white lesions on genitals | condylomata lata (2° syphilis) |
Splinter hemorrhages in fingernails | bacterial endocarditis |
“strawberry tongue” | scarlet fever, Kawasaki disease, toxic shock syndrome |
Ulcerated genital lesions with exudates (painful) | Chancroid (Haemophilus ducreyi) |
Urethritis, conjunctivitis, arthritis in a male | Reiter’s syndrome (reactive arthritis associated with HLA-B27) |
Vasculitis from exposure to endotoxin causing glomerular thrombosis | Schwartzman reaction |
WBC casts in urine | acute pyelonephritis |
Weight loss, diarrhea, arthritis, fever, adenopathy | Whipple’s disease (Tropheryma whippelii) |
Constrictive pericarditis in devel. world | M. tuberculosis |
Death in CML | blast crisis |
DIC | gram-negative sepsis, cancer, burn trauma |
Food poisoning | S. aureus, B. cereus, C. botulinum, E. coli |
Gene involved in cancer | p53 tumor suppressor gene |
Glomerulonephritis (adults) | Berger’s Disease (IgA nephropathy) |
Heart valve in bacterial endocarditis | mitral (rheumatic fever), tricuspid (IV drug abuse), aortic (2nd affected in rheumatic fever) |
Helminth infection (US) | 1. Enterobius vermicularis 2. Ascaris lumbricoides |
Aortic aneurysm, ascending | Tertiary syphilis |
Autosplenectomy (fibrosis and shrinkage) | sickle cell anemia (HbS) |
Bacteremia/pneumonia (IV drug user) | S. aureus |
Bacteria associated with stomach cancer | H. pylori |
Bacterial meningitis (adults and elderly) | H. influenza, N. meningitidis, S. pneumoniae |
Bacterial meningitis (newborns and kids) | Group B streptococcus (newborns), S. pneumoniae/N. meningitidis (kids) |
Bleeding disorder with gp1b deficiency | Bernard-Soulier disease (defect in platelet adhesion—receptor for vWF) |
2ary bug in viral pneumonia patient | Klebsiella, S. pneumoniae |
Hepatocellular carcinoma | Hep B and C (cirrhotic liver) |
Hereditary bleeding disorder | von Willenbrand's disease (low Factor VIII) |
HLA-B27 | Ankylosing spondylitis, Reiter's syndrome |
Infection in blood transfusion | Hep C |
Kidney stones | struvite (ammonium) = radiopaque (Proteus or Staph) |
Malignancy associated with noninfectious fever | Hodgkin's Lymphoma |
Mitral valve stenosis | Rheumatic heart disease |
Myocarditis | Coxsackie B |
Neoplasm (KIDS) | ALL |
Pneumonia in AIDS pts | pneumocystis jiroveci (PCP), cytomegalovirus, Mycobacterium avium-intracellulare, aspergillosis, candidiasis |
Osteomyelitis in noncompromised pts | S. aureus |
Osteomyelitis in patients with sickle cell disease | Salmonella |
Osteomyelitis with IV drug abuse | Pseudomonas |
Patient with ALL/CLL/AML/CML | ALL: child, CLL: adult>60, AML: adult>60, CML: adult 35-50 |
Hodgkin's disease | young male (except nodular sclerosis type: female) |
Pelvic inflammatory disease | Neisseria gonorrhoeae (monoarticular arthritis) |
Philadelphia chromosome | CML (bcr-abl) |
Pneumonia, hospital acquired | gram-negatives (52%), MRSA (19%), Haemophilus spp. (5%) |
ICU pneumonia (nosocomial) | S. aureus (17.4%), P. aeruginosa (17.4%), Klebsiella & Enterobacter spp. (18.1%), H. influenzae (4.9%) |
Primary bone tumor (adults) | MM (multiple myeloma) |
t(14;18) | Follicular lymphoma (bcl-2 activations) |
t(8;14) | Burkitt's Lymphoma (c-myc) |
t(9;22) | Philadelphia Chromosome; CML (bcr-abl |
Type of non-Hodgkins | Diffuse large cell |
UTI | E. coli, S. saprophyticus |
Viral encephalitis | HSV |
Aortic aneurysm, ascending | Tertiary syphilis |
Autosplenectomy (fibrosis and shrinkage) | sickle cell anemia (HbS) |
Bacteremia/pneumonia (IV drug user) | S. aureus |
Follicular lymphoma (bcl-2 activations) | Follicular lymphoma (bcl-2 activations) |
Burkitt's Lymphoma (c-myc) | t(8;14) |
t(9;22)Philadelphia Chromosome; CML (bcr-abl) | t(9;22) |
Type of hodgkin's | nodular sclerosis (vs mixed cellularity, lymphocity predominance, lymphocytic depletion) |
UTI | E. coli, S. saprophyticus |
Viral encephalitis | HSV |
Adrenal hemorrhage, Hypotension, DIC | Waterhouse-Friderichsen syndrome (meningococcemia) |
Indurated, ulcerated genital lesions (nonpainful) | chancre (primary syphilis) |
Bacteremia/pneumonia (IVDA) | S. aureus |
Bacteria found in GI tract | Bacteroides (2nd most common is E. coli ) |
Epiglottitis | Haemophilus influenzae type B |
Heart valve (rheumatic fever) | Mitral valve (aortic is 2nd) |
Heart valve in bacterial endocarditis | Mitral |
Heart valve in bacterial endocarditis in IVDA | Tricuspid |
Primary bone tumor (adults) | Multiple myeloma |
Type of non-Hodgkin’s | Follicular, small cleaved |
Viral encephalitis | HSV |