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Test-3-Physiology
Neurophysiology - Action Potentials
Question | Answer |
---|---|
what are 6 types of Neuroglial Cells? Hint 4 are in the CNS and 2 in the PNS. | CNS: Oligodendrocytes, Astrocytes, Microglia, Ependymal Cells //// PNS: Schwann Cells and Satellite Cells |
Of the 6 types of Neuroglial cell which ones form myelin for the PNS and CNS? | CNS: Oligodendrocytes //// PNS: Schwann Cells |
Astrocytes help form the blood brain barrier (BBB), but what else do they do with in the CNS? | Nourish the Neurons |
What neuron is only located in the CNS, efferent, afferent, oligodendrocytes, or Interneurons? | InterNeurons |
Cellular charge difference is the ratio of what two things? | ECF:ICF |
By convention the ECF is considered the ground and has what charge in mV? | 0 |
All cells have electrical properties but not all can transmit electrical impulses, true or false? | TRUE |
A neuron at Rest has more or less Na, K, and Cl inside the cell? | MORE - K (155mM) // LESS - Na (10mM), and Cl (7mM) |
Energy is not required for an axon potential, true or false? | True - its diffusion |
At rest what is the Na and K gradient? | Na Negative 130 mV, and K is positive 20 mV |
Which Ion channel Opens and closes slowly? | K. //// Na - Open and inactivate very rapidly (ball and chain looking thing moves to open and inactivate Na channels) |
Why does the cell dip below resting potential when repolarization occurs? | Persistent current through SLOWLY closing voltage gated K channels allows K to keep coming into cell. Does not have "ball and chain" like sodium to close quickly. |
During what refractory period can a greater than normal stimulus cause an action potential? | Relative refractory period. The distance to threshold is higher membrane is hyperpolarized (more negative), this is why it would take a greater stimulus. |
When can no stimulus trigger an Action Potential? Absolute or Relative refractory period? | Absolute Refractory Period. |
During relative refractory period what kind of stimulus would you need to cause firing of the nerve? | Increased compared to normal. |
When action potentials jump from one node to the next as they propagate along a myelinated axon is called what kind of conduction? | Saltatory Conduction |
The propagation of the action potential from the dendritic to the axon terminal end is one way why? | Because of the ABSOLUTE refractory period. Impulse can only move one way. |
When more then one nerve affects one nerve this is referred to as? | Convergence.//// Divergence is just the opposite (one nerve depolarizes many nerves). |
To terminate a signal in the chemical synapse the neurotransmitter must be removed, what three things happen to accomplish this? | 1.Diffusion of trans from the cleft /// 2.Degradation of the transmitter by enzymes /// 3.Reuptake into the pre-synaptic cells for reuse. |
What are neurotransmitters produced and stored in? | Vesicles at the axon terminal. |
When the cell is stimulated what happens to Ca levels at the axon terminal? | Ca levels INCREASE into axon to stimulated vesicles to translocate and bind to the plasma membrane via SNARE proteins & exocytosed into synaptic space. |
Membran potential of a real neuron typically undergo many EPSPs (excitatory PostSynaptic Potentials) and IPSPs, true or false? | True |
Until threshold is reached its all about what kind of gated channels? Compared to once threshold is reached and rapid Voltage-gated Na open to initiate an Action Potential. | Mechanical or Ligand gated channels |