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Turnicky 02 Hypo/Mic
Trunichy: Hypochromic Microcytic Anemia
Question | Answer |
---|---|
Deficiency in __ or ___ | Heme or globin chain synthesis |
Result of deficiency in heme synthesis | Iron deficiency |
Result of deficiency in globin synthesis | Thalassemia |
Major storage form of iron | Ferritin |
Ferritin synthesis is directly proportional to... | Total iron stores |
Long term storage form of iron | Hemosiderin |
What stain is used to see hemosiderin? | Prussian blue |
Serum iron binding protein | Transferrin |
Serum iron measures... | Transferrin bound iron |
Use TIBC to discriminate between ___ and ___ | IDA and ACD |
Normal transferrin saturation | 30% |
Pt presents with: Decreased serum ferritin Decreased serum iron Increased TIBC Decreased %saturation What's the Dx? | Iron deficiency anemia |
Two substances that can cause Acquired Sideroblastic Anemia | Alcohol and Lead |
Inhibitory cytokines that adversely impact erythropoiesis | TNF-B IL-1/6 INF-gamma Hepcidin |
One of the most common human diseases | IDA |
Soluble iron storage form | Ferritin |