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Study Guide Ch 13

Chabner, Language of Medicine 8th Edition, Chpt 13 Blood System

QuestionAnswer
white blood cell with reddish granules, numbers INCREASE in allergic reactions eosinopohil
Protein threads that form the basis of a clot FIBRIN are protein "threads" formed from fibrogen. (Don't confuse with platelets which are thrombin "cells")
Method of separating plasma proteins by electrical charge Electrophoresis
foreign material that invades the body antigens
pigment produced from hemogloblin when red blood cells are destroyed (hemolysis) bilirubin
an undifferentiated blood cell is called an Hematopoetic stem cell (when stem cells have not yet changed into mature forms they are are categorized "diffrentiated")
anticoagulant found in the blood heparin - the body's natural anticoagulant
a disorder of Red Blood Cell MORPHOLOGY is Poikilocytosis (abnormally formed red blood cells characteristic of various anemias)
Deficiency in numbers of white blood cells (in this case, a deficiency of neutrophils) neutropenia
an immature red blood cell is a...? erythroblast (erythr/o = red, -blast = immature cell)
derived from bone marrow myeloid (myel = bone marrow, -oid = derived/resembling)
Breakdown of recipient's red blood cells when incompatible bloods are mixed hemolysis (hemo = blood, -lysis)
NAME THAT ANEMIA! Sideropenia occurs, causing deficient production of hemoglobin. iron-deficiency anemia (sideropenia - low iron anemia)
NAME THAT ANEMIA! Reduction in red cells due to excessive cell destruction. hemolytic anemia (hemo = blood, -lytic = pert to breakdown/separation/destruction)
NAME THAT ANEMIA! Failure of blood cell production due to absence of formation of cells in the bone marrow. APLASTIC ANEMIA - (aplastic = not exhibiting growth or change in structure)(anemia = a condition in which the blood is deficient in red blood cells, in hemoglobin, or in total volume)
NAME THAT ANEMIA! Inherited defect in ability to produce hemoglobin. Thalassemia (aka: Mediterranean anemia )
NAME THAT ANEMIA! Lack of mature red cells - due to - inability to absorb vitamin B12 into the body Pernicious Anemia (pernicious = highly injurous or destructive)
excessive deposits of iron throughout the body hemochromatosis (hem/o = blood, chromat/o = colored, -osis = abnormal condition)
symptoms of pallor, shortness of breath, infection, bleeding gums, predominance of immature and abnormally functioning leukocytes, and low numbers of mature neutrophils in a young child may indicate a likely diagnosis of Acute Lymphocytic Leukemia (aka: ALL) marked by an abnormal increase in the number of lymphoblasts, characterized by rapid onset and progression of symptoms on front flap of this flashcard.
Excessive bleeding caused by congenital lack of factor VIII or IX Hemophilia (hem/o = blood, -philiac = pert to a "tendency" toward) Hemophiliac - tends to bleed.
venous blood is clotted in a test tube to measure...? coagulation time (15-20 minutes is the normal range)
Sample of blood is spun in a test tube so that red cells fall to the bottom and percentage of RBCs is taken Hematocrit (hemat/o = blood, -crit = count/judge/guage)
blood smear is examined to determine the shape or form (morphology) of cells. Red blood cell morphology (study of shape/change)
leukocytes are stained and counted under a microscope to see numbers of mature and immature forms WBC differential (differential is the change which occurs as cells mature from their immature forms)
venous blood is collected; anti-coagulant added and the distance cells FALL in period of time is determined in this test... sedimentation rate
A "Red Blood Cell" erythrocyte (erythr/o = red, -cyte = cell)
(type of cell) "white blood cell; phagocyte, and is a precursor of a macrophage" monocyte (mon/o = one, single) (-cyte = cell, in this case, the nucleus)
term meaning "thrombocyte" platelet
term meaning "bone marrow cell; gives rise to many types of blood cells" Hematopoietic Stem Cell
term meaning "leukocyte formed in lymph tissue; produces antibodies LYMPHOcyte (produced in Lymph tissues)
term meaning "leukocyte with dense, REDDISH granules; associated with ALLERGIC reactions Esinophil(s)
term meaning "leukocyte (poly) formed in bone marrow and having NEUTRAL-staining granules Neutrophil(s)
term meaning "leukocyte whose granules have an affinity for BASIC stain; releases histamine and heparin Basophil(s)
concerning blood cells, this is a term for "irregularity in shape" poikilocytosis
deficiency in numbers of RBCs erythrocytopenia (erythr/o = red, cyt/o = cell, -penia = deficiency)
reduction of hemoglobin ("color") Hypochromic (hypo- = decreased, chrom/o = color, -ic = pert to.)
increase in numbers of SMALL cells Microcytosis (micro = small, cytosis = condition of cells)
erythremia (characterized by an increase in total blood volume and viscosity and typically accompanied by nosebleed, headache, dizziness, weakness, etc) polycythemia vera
increase in numbers of LARGE cells macrocytosis (macro- = large, cytosis = condition of cells)
formation of red cells (as from the bone marrow) erythropoiesis (erythr/o = red, -poiesis = formation)
destruction of red cells hemolysis (hem/o = blood, -lysis = destruction / separation / breakdown
relieving, but not curing pallative
deficiency of ALL blood cells pancytopenia (pan- = all, cyt/o = cell, -penia = deficiency)
increase in numbers of granulocytes; seen in allergic conditions eosinophilia (eosin/o - red, dawn, rosy) (-philia = attraction, tendency, increase in cells)
symptoms of disease return is called _______? relapse
MULTIPLE pinpoint hemorrhages (multiple petechiae formations) purpura (characterized by patches of purplish discoloration resulting from extravasation of blood into the skin and mucous membranes)
the separation of blood into it's components is called ? apheresis (-apheresis = removal, carry away), usually termed as plasmapheresis
symptoms of disease disappear the patient is in ______? remission
A stained blood smear is examined to determine the shape of individual red blood cells, this test/exam is called...? RBC Morphology
this test measures the percentage of red blood cells in a volume of blood hematocrit
this test determines the number of clotting cells per cubic millimeter platelet count
(this tests the) Ability of venous blood to clot in a test tube Coagulation Time
(this test) Measures the speed at which erythrocytes SETTLE outside of plasma Erythrocyte Sedimentation Rate
(this test) Determines the numbers of different types of WBCs the WBC Differential
(this test) Determines the presence of antibodies in infants of Rh-negative women or patients with autoimmune hemolytic anemia COOMBS TEST
(this procedure employs) Undifferentiated blood cells from a donor, infused into a patient being treated for leukemia or aplastic anemia Hematopoietic stem cell transplant
The time it takes for a small puncture wound to stop bleeding is called ? bleeding time test
(procedure where a) Needle is introduced into the bone marrow cavity, and a small amount of marrow is aspirated and then examined under the microscope Bone Marrow Biopsy
(procedure where) Blood is collected from and later reinfused into the same patient Autologous Transfusion
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