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68wm6 p2 Inf Dis Ner
Inflammatory and Infectious Disorders of the Nervous System
Question | Answer |
---|---|
What infections can cause meningitis? | Ear, Nose, and Blood |
What are the causes of meningitis? | Bacterial, Viral, and Fungal |
What is Brudzinskis Sign? | Flexion of the neck produces flexion of the hips and knees |
What is Kertigs Sign? | Inability to extend the leg when the thigh is flexed on the abdomen without extreme pain. |
What is Opisthotonos? | An extreme hyperextension of the neck and arching of the back. |
List 5 S/Sx of meningitis: | *Fever *Nuchal rigidity (Neck stiffness) *N/V *Altered LOC *Photophobia *Kernigs sign *Brudzinskis sign *Opisthotonos |
Antibiotics given for meningitis need to be able to do what? | Cross the blood brain barrier |
What are hyperosmolar agents? | Agents effective in reducing ICP through 1)Plasma expansion w/decrease in hematocrit and cerebral blood volume 2)draws CSF from brain into circulation |
The bed of a PT with meningitis must be placed how? | HOB elevated |
Encephalitis is most often caused by what? | A virus (measles, chicken pox, mumps ect..) |
When is encephalitis more prevalent? | After flu epidemics |
What form of encephalitis is a common complication of AIDS? | Cytomegalovirus Encephalitis |
What S/Sx seperate Meningitis and Encephalitis? | *Visual disturbances *Tremor/ Muscle weakness *Lack of coordination *Spastic/flaccid paralysis *Convulsions |
What medications are given to control ICP? | *Hyperosmolar agents *Mannitol *Corticosteroids |
What can be given to reduce the mortality from Herpes Simplex encephalitis from 70%-30%? | Antivirals (Acyclovir is prefered due to fewer side effects) |
What is Guillian-Barre Syndrome (GBS)? | Widespread inflammation and demyelination of the peripheral nervous system. Antibodies attack the schwann cells which compose the myelin sheath. Uninsulated nerve inflames, interrupting nerve transmission. |
What are the first symptoms of Guillian-Barre Syndrome (GBS)? | Motor weakness and numbness/tingling |
Where does the symptoms of GBS start? | Lower extremities, then move upward |
How does remyelination occur in GBS? | demyelination is self limiting. Remylination occurs in revers, starting at upper extremities and moves downward. |
When is a craniotomy indicated in a brain abscess? | If the abscess is encapsulated and antimicrobial therapy cant reach it. |