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Med Neuro2 Lect7
Med Neuro2 Lect7 Vestibular I
Question | Answer |
---|---|
What are the 5 receptor-organs in the vestibular apparatus? | 1.Macula Saccule. 2.Macula Untricle. 3.Anterior semicircular canal. 4.Horizontal semicircular canal. 5.Posterior semicircular canal. |
Defects in the vestibular system would cause what symptoms? | 1.Dizziness. 2.Loss of balance. 3.Vertigo. |
What fluid are the vestibular receptor-organs embedded in? | Endolymph |
Each semicircular canal terminates into a ________? | Ampulla, then all 3 come together at the vestibule. |
Describe the structure of the Macula sacula and Macula utricle | Two rows of hair cells with striola b/w them that for 90 degree angles. **One of these two will be positioned to detect the pull of gravity at all times. |
How does Endolymph enter the vestibular organ? where does it come from? | The Saccule is connected to the base of the cochlea allowing endolymph to flow from the the scala media. **Produced by the Stria Vascularis. |
What is located inside each Ampulla found at the end of each semicircular canal? What is located in them? | Crista. **Vestibular nerve of CNVIII is located here for the depolarized hair cells to release vesicles onto. |
When Vestibular hair cells are stimulated, what is actually moving to open up ion channels leading to their depolarization? | Fluid bends the Cupula which extends across the ampulla and moves about the Crista of the Ampulla. **it is connected to sterocilia which are attached to the hair cell. |
What is the large sterocilia connecting the hair cells on the Crista to the Cupula called? | Kinocilium |
Bending of the sterocilia towards or away from the Kinocilium will can a Ca+ influx into the hair cell? | Bending TOWARDS the Kinocilium will Inc Ca+ influx. **Bending away from the Kinocilium will dec Ca+ influx. |
What is the firing rate by the vestibular hair cells dependent on? | Movement of the Cupula (thus sterocilia) towards or away from the Kinocilium. **Dischare rate is spontaneous. |
What direction of fluid movement within the Anterior semicircular canal will cause sterocilia movement towards the Kinocilium? | Into/towards the canal. |
What direction of fluid movement within the Posterior semicircular canal will cause sterocilia movement towards the Kinocilium? | Into/towards the canal. |
What direction of fluid movement within the Horizontal semicircular canal will cause sterocilia movement towards the Kinocilium? | Towards the utricle. **Away/out of the canal. |
Are the stereocilia of the vestibular hair cells symmetrical or asymmetrical? | ASYMMETRICAL. (large Kinocilium) |
Compare the firing rate of the R and L vestibular hair cells in the horizontal semicircular canal when the head is neutral | They will be the SAME |
Compare the firing rate of the R and L vestibular hair cells in the horizontal semicircular canal when the head is turned to the left | Firing rate is Inc on the L and Dec on the R. **Stereocilia will be bent towards L kinocilium, away from Kinocilium on the R. |
Compare the firing rate of the R and L vestibular hair cells in the horizontal semicircular canal when the head is turned to the right? | Firing rate is Inc on the R and Dec on the L. **Stereocilia are bending towards kinocilium on the R, away from the Kinocilium on the L. |
Where do the signals from the vestibular organ travel from the hair cells? | The vestibular nuclei transmits them back CN VIII which projects to the midline to the Median Longitudinal Fasciculus. **Runs the length of the brainstem & connects CN III, IV, & VI. |