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GU 1 Norm Renal Fn
Normal Renal Function and Diuretics
Question | Answer |
---|---|
What is the catalyst for bicarb resorption into the proximal convoluted tubule? | Carbonic anhydrase |
Why are loop diuretics so effective in treating pulmonary edema 2/2 fluid overload? | They have direct pulmonary vasodilatory activity |
What is the tx for acromegaly? | Transphenoidal resection= #1 option. Also octreotide, cabergoline, pegvisomant, or external beam radiation. |
A pt with cirrhosis presents to the ER to have his recurrent ascites drained. Analysis of the ascites fluid reveals an absolute neutrophil count >250cells/mm3. What is the dx? | SBP |
What are the protein and LDH criteria for an exudative pleural effusion? | Pleural:serum protein ratio >0.5 Pleural:serum LDH ratio >0.6 |
What type of diuretic is triamterene? | K sparing |
What type of diuretic is acetazolamide? | carbonic anhydrase inhibitor |
What type of diuretic is HTZ? | thiazide |
What type of diuretic is bumetanide? | loop |
What type of diuretic is spironolactone? | K sparing, aldosterone antag |
What type of diuretic is chlorothiazide? | thiazide |
What type of diuretic is ethacrynic acid? | non-sulfa loop |
What type of diuretic is mannitol? | osmotic |
What type of diuretic is metolazone? | thiazide (can be used to tx cirrhotic ascites). HY! |
What type of diuretic is furosemide? | loop |
What type of diuretic is amiloride? | K-sparing |
What type of diuretic is torsemide? | loop |
What is the best diuretic (or diuretic class) for each situation?: acute pulmonary edema | loops (LMNOP) |
What is the best diuretic (or diuretic class) for each situation?: idiopathic hypercalciURIA causing calcium stones | thiazides (hold onto calcium) |
What is the best diuretic (or diuretic class) for each situation?: glaucoma | mannitol or acetazolamide |
What is the best diuretic (or diuretic class) for each situation?: mild to moderate CHF with expanded ECV | Loops (increase dose to decrease volume), spironolactone |
What is the best diuretic (or diuretic class) for each situation?: in conjunction with loop or thiazide diuretics to retain K | spironolactone |
What is the best diuretic (or diuretic class) for each situation?: edema a/w nephrotic syndrome | loop |
What is the best diuretic (or diuretic class) for each situation?: increased intracranial pressure | mannitol |
What is the best diuretic (or diuretic class) for each situation?: mild to moderate HTN | thiazide |
What is the best diuretic (or diuretic class) for each situation?: hypercalcemia | loop |
What is the best diuretic (or diuretic class) for each situation?: altitude sickness | acetazolamide |
What is the best diuretic (or diuretic class) for each situation?: hyperaldosteronism | spironolactone or eplerenone |