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Gyne 6 Gyn Neoplasms
Gynecologic Neoplasms
| Question | Answer |
|---|---|
| What is the antidote to each of the following toxins?: anticholinesterases, organophosphates | atropine, pralidoxine |
| What is the antidote to each of the following toxins?: mercury | dimercaprol, succimer |
| What is the antidote to each of the following toxins?: carbon monoxide | 100% O2 and hyperbaric O2 |
| What is the antidote to each of the following toxins?: heparin | protamine sulfate |
| What is the antidote to each of the following toxins?: isoniazid | pyridoxine (B6) |
| What is the lab w/u for AUB? | beta hCG, pap smear, wet prep, CBC, coag studies, TSH, +/- endometrial bx |
| A pt presents with a painless, pruritic papule with regional lymphadenopathy that evolves over 7-10d into a necrotic ulcer with a black eschar. What is the dx and tx? | Cutaneous anthrax, penicillin V, penicillin G, ampicillin, and doxycycline |
| What is the most important staging facotr in the prognosis of endometrial CA? | The grade (more important than depth) |
| When should cervical cancer screening begin? | Age 21 |
| When can you stop screening for cervical cancer? | Age 65-70 with serial normal paps. If they had a hysterectomy for benign reasons, paps may be discontinued indefinitely. |
| What is the general tx strategy for SCC of the vagina? | Radiation. If less than 2cm, may be able to do surgical excision |
| What are the indications for an endometrial bx? | Abnormal uterine bleeding, menometrorrhagia or post menopausal bleeding in a woman >35, post-menopausal bleeding. If <35yo, menometrorrhagia + signif risk factors for cancer. |
| What is the next step in the mgmt of a CIN 2 cervical lesion identified on bx in a woman who has completed fertility? | LEEP or conization or laser ablation |
| What is the next step in the mgmt of an ASCUS Pap smear with a negative HPV test? A positive HPV test? | Neg HPV: repeat pap in 3-6mos Pos HPV: colpo |
| What is the next step in mgmt of an AGUS pap smear? | Colpo with endocerv curretage. Endometrial bx if ?35yo or risk factors for CA. |
| What is the tx for a lesion found to be HSIL on bx? | LEEP or cone or laser ablation |
| What are the sx of ovarian cancer? | Early: asymptomatic. Late: abdominal pain, wt loss, ascites, palpable mass, fatiuge, changes in menstrual and bowel habits |
| What are the risk factors for endometrial cancer? | Unopposed E stimulation, early menarche, late menopause, PCOS, obesity, nulliparity, tumor, exogenous E, DM, HTN, age, high fat diet, and colon CA |
| What are the risk factors for ovarian CA? | frequent ovulation, nulliparity, BRCA mutations, family hx |
| What serum marker may be elevated in cases of endometrial CA? | CA-125 |
| What serum marker may be elevated in cases of ovarian CA? | CA-125 |
| What US findings are consistent with benign ovarian tumors? WIth malignant ovarian tumors? | Benign: Cystic, smooth edges, few septa. Malignant: irregularity, nodulatiry, septa, pelvic extension. |
| What type of ovarian tumor is a/w psammoma bodies? | serous cystadenocarcinoma |
| What type of ovarian tumor is a/w estrogen excess? | granulosa-theca cell tumor |
| What type of ovarian tumor is a/w androgen secretions? | sertoli-leydig cell tumor |
Created by:
sarah3148
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