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Pulmonary II - Pneumonias

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Question
Answer
show Inflammatory consolidative process involving the lung parenchyma  
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show Steptococcus pneumoniae 60-80% of all bacterial pneumonias  
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Organism most commonly involved in pneumonias occurring after viral infection   show
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show (1) Aerogenous (2) Hematogenous (3) Direct Traumatic introduction(1) Aerogenous (2) Hematogenous (3) Direct Traumatic introduction  
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What are the effect of alcohol on the immune system   show
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show Alveolar hypoxia and mucus stasis  
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Why is CHF a risk factor for bacterial pneumonia infections?   show
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show Strepococcus pneumoniae pneumonias. Asplenia secondary to autoinfarction is a complication of sickle cell anemia. Aspelnic patients are susceptible to infections caused by encapsulated bacterial organisms such as Steptococcus penumoniae, Haemophilus infl  
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Why are cystic fibrosis patients susceptible to recurrent bouts of pneumonia?   show
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show Azotemia  
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What conditions result in the loss of cough reflex?   show
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Symptoms of Bacterial Pneumonia   show
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Chest x-ray findings of Bacterial Pneumonia   show
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Stages of Bacterial Pneumonia   show
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Morphologic change in Pneumonia: Congestion and Edema   show
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Morphologic change in Pneumonia: Red hepatization   show
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Morphologic change in Pneumonia: Gray hepatization   show
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show Occurs Day 8 to 21. Microscopically characterized by the clearing of exudates and the reestablishment of normal structure/function.  
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show Brochiectasis  
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What is a complication found in 20-30% of patients with lobar pneumonia?   show
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A lung pathology characterized as a collection of pus in the pleural space. Found in 1% of all treated pneumonia infections. Characterized by persistent fever following apparent recovery from the infection   show
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Complications of bacterial pneumonia   show
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show Lung Abscess  
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show Typically polymicrobial. Specific organisms include anaerobes, Klebsiella, Pseudomonas, Legionella, Staphylococcus type III, Streptococcus, and anaerobic necrotizing pneumonias.  
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show (1) Accidental inhalation or aspiration of necrotic/caustic material from stomach, oral cavity, or nasopharynx(2) Necrotizing pneumonias (3) Septic embolus from distant infection (4) Pulmonary trauma (5) Secondary infection of bullae in emphysema patients  
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A lung pathology characterized as persistent dilatation of bronchi, associated with loss of distal and surrounding lung parenchyma typically caused by chronic inflammation and necrosis.   show
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What area of the lung most commonly involved in bronchiectasis?   show
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What is the primary cellular response to viral pneumonia   show
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show Respiratory syncytial virus  
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show Herpes zoster virus  
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show CMV. Has 80% mortality.  
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show CMV  
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Symptoms of viral pneumonia   show
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What percentage of chicken pox patients develop Varicella zoster pneumonia?   show
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show Inflammation is more interstitial and less exudative. Immune response is characterized by lymphocytes and monocytes/macrophages. Most severe forms histologically and clinically resemble Diffuse Alveolar Damage (DAD) or Acute Interstitial Pneumonia (AIP)  
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show (1) Mycoplasma (2) Chlamydia (3) Rickettsia  
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An immune reaction mediated by T cells interacting with monocyte/macrophages. Accumulation of macrophages (epithelioid cells) surrounded by a rim of lymphocytes often with an outer rim of fibrous tissue. Epithelioid cells may fuse to become giant cells.   show
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show (1) Gold standard – culture (2) Microscopy with acid-fast stain (3) Molecular diagnostics  
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show True  
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show False  
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(T or F) Wegener’s Granulmoatosis is associated with necrotic granulomatous inflammation   show
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Occurs in individuals who have not primarily been exposed to tuberculosis bacteria; often children. Often asymptomatic.   show
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show False  
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Ghon complex   show
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What does a positive PPD result indicate?   show
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show (1) fever (mid-afternoon) (2) night sweats (3) weakness/fatigability (4) loss of appetite (5) blood-streaked sputum (6) cough (7) dyspnea  
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show The apical or posterior segments of the upper lobe where secondary pulmonary tuberculosis infection typically begins. The higher PO2 of the upper lobe favor Mycobacterium tuberculosis.  
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Descirbe a pulmonary tuberculosis Lesion   show
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A complication of secondary tuberculosis infection. Seeding of distant organs by lymphatic or hematogenous spread. Infected organs are covered with small millet seed-like lesions.   show
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(T or F) Cavitation is seen in both primary and secondary tuberculosis infections.   show
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show Mycobacterium avium-intracellulare  
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show Mycobacterium kansasii  
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show False. Histologically, it is characterized by non-coalescing granulomas randomly scattered in the parenchyma. Granulomas have a lymphocytic cuff and are non-caseating.  
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Endemic area for Histoplasmosis   show
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Endemic area for Blastomycosis   show
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Endemic area for Coccidiomycosis   show
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show Worldwide  
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show Ubiquitous and nosocomial  
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Endemic area for Candidiasis   show
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show Soils contaminated by bird droppings  
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Microscopy of Histoplasmosis   show
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show Yeasts with broad-based buds (5-25 um)  
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show Similar to tuberculosis with latent, primary, disseminated and chronic states  
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show Primary infection is pulmonary. Dissemination is common and usually to skin. Lung disease can be solitary or progressive.  
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show Thick-walled, non-budding spherule 20-60um in diameter filled with endospores  
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Describe the clinical disease of Coccidioidomycosis   show
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Source of Coccidioidomycosis   show
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show Soil contaminated with pigeon droppings  
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Morphology of Cryptococcosis   show
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Describe the clinical disease of Cryptococcosis   show
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Morphology of Aspergillosis   show
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show Aspergillosis  
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show Secondary colonization of tumors by aspergillosis  
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What is allergic Bronchopulmonary Aspergillosis?   show
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Morphology of Mucormycosis   show
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show Capable of being angioinvasive, necrotizing, or form fungal balls  
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show Budding yeast and pseudohyphae  
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show (1) Immunocompromised states (2) Deep infections (3) Patients with indwelling venous catheters (4) Prolonged antibiotic use (5) Severe burns (6) Major abdominal surgery  
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Predisposing conditions for Fungus Ball Formation   show
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show True  
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Opportunistic pneumonia that commonly occurs in AIDS patients.   show
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Histopathologic features of PCP   show
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Morphology of Pneumocystis carinii   show
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show Lipid pneumonia  
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Pathogenesis of aspiration of large particle   show
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Pathogenesis of aspiration of gastric contents   show
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