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Psychophysiology with slide images

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Term
Definition
Neuraxis   show
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anterior   show
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show with respect to the cns, located near or toward the tail  
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rostral   show
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show "toward the tail"; with respect to the cns, in a direction along the neuraxis away from the front of the face  
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show "toward the back"; with respect to the cns, in a direction perpendicular to the neuraxis towards the top of the head or the back  
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ventral   show
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show toward the side of the body, away from the middle  
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medial   show
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ipsilateral   show
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contralateral   show
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show with respect to the cns, a slice taken at right angles to the neuraxis  
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show a slice through the brain parallel to the ground  
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show a slice through the brain parallel to the neuraxis and perpendicular to the ground  
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midsagittal plane   show
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show the three layers of tissue that encase the cns: the dura mater, arachnoid membrane, and pia mater  
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dura mater   show
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arachnoid membrane   show
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show the layer of the meninges that clings to the surface of the brain; thin and delicate  
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subarachnoid space   show
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cerebrospinal fluid   show
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ventricle   show
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lateral ventricle   show
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show the ventricle located in the center of the diencephalon  
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show a narrow tube interconnecting the third and fourth ventricles of the brain, located in the center of the mesencephalon  
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show the ventricle located between the cerbellum and the dorsal pons, in the center of the metencephalon  
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show the highly vascular tissue that protrudes into the ventricle and produces cerebrospinal fluid  
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arachnoid granulation   show
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superior sagittal sinus   show
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obstructive hydrocephalus   show
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show a hollow tube, closed at the rostral end, that forms from ectodermal tissue early in embryonic development; serves as the origin of the cns  
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show the outermost layer of gray matter of the cerebral hemispheres  
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progenitor cells   show
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show a layer of cess that line the inide of the neural tube; contains progenitor cells that divide and give rise to cells of the cns  
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subventricular zone   show
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show division of a progenitor cell that gives rise to two identical progenitor cells; increases the size of the ventricular zone and hence the brain that develops from it  
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asymmetrical division   show
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show special glia with fibers that grow radially outward from the ventricular zone to the surface of the cortex; provide guidance for neurons migrating outward during brain development  
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apoptosis   show
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show production of new neurons through the division of neural stem cells; occurs in the hippocampus and olfactory bulb and appears to play a role in learning  
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forebrain   show
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cerebral hemisphere   show
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show the region located within the brain, beneath the cortical surface  
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show a groove in the surface of the cerebral hemisphere, smaller than a fissure  
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show a major groove in the surface of the brain, larger than a sulcus  
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gyrus   show
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primary visual cortex   show
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calcarine fissure   show
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primary auditory cortex   show
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show the fissure that separates the temporal lobe from the overlying frontal and parietal lobes  
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primary somatosensory cortex   show
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central sulcus   show
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show a sunken region of the cerebral cortex that is normally covered by the rostral superior temporal lobe and caudal inferior frontal lobe  
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primary motor cortex   show
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frontal lobe   show
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show the region of the cerebral cortex caudal to the frontal lobe and dorsal to the temporal lobe  
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show the region of the cerebral cortex rostral to the occipital lobe and ventral to the parietal and frontal lobes  
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show the region of the cerebral cortex caudal to the parietal and temporal lobes  
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show those regions of the cerebral cortex that receive information from the regions of primary sensory cortex  
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motor association cortex   show
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prefrontal cortex   show
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corpus callosum   show
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neocortex   show
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limbic cortex   show
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cingulate gyrus   show
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limbic system   show
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show a structure in the interior of the rostral temporal lobe, containing a set of nuclei; part of the limbic system  
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fornix   show
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show a protrusion of the bottom of the brain at the posterior end of the hypothalamus, containing some hypothalamic nuclei; part of the limbic system  
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show a group of subcortical nuclei in the telencephalon, the caudate nucleus, the globus pallidus, and the putamen; important parts of the motor system  
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nucleus   show
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diencephalon   show
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show the largest portion of the diencephalon, located above the hypothalamus; contains nuclei that project information to specific regions of the cerebral cortex and receive information from it  
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projection fiber   show
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show a group of cell bodies within the lateral geniculate body of the thalamus that receives fibers from the retina and projects fibers to the primary visual cortex  
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medial geniculate nucleus   show
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show a nucleus of the thalamus that receives inputs from the cerebellum and sends axons to the primary motor cortex  
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show the group of nuclei of the deincephalon situated beneath the thalamus; involved in regulation of the autonomic NS, control of the anterior and posterior pituitary glands, and integration of species-typical behaviors  
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optic chasm   show
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anterior pituitary gland   show
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show a neuron that secretes a hormone or hormonelike substance  
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show the posterior part of the pituitary gland; an endocrine gland that contains hormone-secreting terminal buttons of axons whose cell bodies lie within the hypothalamus  
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midbrain   show
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show the midbrain; a region of the brain that surrounds the cerebral aqueduct; include the tectum and the tegmentum  
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tectum   show
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superior colliculi   show
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show protrusions on top of the midbrain; part of the auditory system  
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show the "stem" of the brain, from the medulla to the midbrain, excluding the cerebellum  
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tegmentum   show
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reticular formation   show
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show the region of the midbrain surrounding the cerebral aqueduct; contains neural circuits involved in species-typical behaviors  
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show a large nucleus of the midbrain that receives inputs from the cerebellum and motor cortex and sends axons to motor neurons in the spinal cord  
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substantia nigra   show
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show the most caudal of the three major division of the brain; includes the metencephalon and myencephalon  
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cerebellum   show
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cerebellar cortex   show
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deep cerebellar nuclei   show
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cerebellar peduncle   show
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pons   show
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medulla oblongata   show
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show the cord of nervous tissue that extends caudally from the medulla  
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spinal root   show
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show a bundle of spinal roots located caudal to the end of the spinal cord  
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show the anesthesia and paralysis of the lower part of the body produced by injection of a local anesthetic into the cerebrospinal fluid surrounding the cauda equina  
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show the spinal root that contains incoming (afferent) sensory fibers  
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ventral root   show
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spinal nerve   show
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show an axon directed toward the cns, conveying sensory information  
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dorsal root ganglion   show
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show an axon directed away from the cns, conveying motor commands to muscles and glands  
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show a peripheral nerve attached directly to the brain  
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vagus nerve   show
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show the protrusion at the end of the olfactory nerve; receives input from the olfactory receptors  
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show the part of the peripheral NS that controls the movement of skeletal muscles or transmits somatosensory information to the CNS  
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show the portion of the PNS that controls the body's vegetative functions  
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sympathetic division   show
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sympathetic ganglia   show
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sympathetic ganglion chain   show
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show the efferent neuron of the autonomic NS whose cell body is located in a cranial nerve nucleus or in the intermediate horn of the spinal gray matter and whose terminal buttons synapse upon postganglionic neurons in the autonomic ganglia  
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postganglionic neuron   show
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show the inner portion of the adrenal gland, located atop the kidney, controlled by sympathetic verve fibers, secretes epinephrine and norepinephrine  
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parasympathetic division   show
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show a neuron that detects changes in the external or internal environment and sends information about these changes to the CNS  
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show a neuron located within the CNS that controls the contraction of a muscle or the secretion of a gland  
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show a neuron located entirely within the CNS  
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show the brain and spinal cord  
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show the part of the nervous system outside the brain and spinal cord, including the nerves attached to the brain and spinal cord  
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show the cell body of a neuron that contains the nucleus  
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show a branched, treelike structure attached to the soma of a neuron; receives informtion from the terminal buttons of other neurons  
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synapse   show
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axon   show
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show a neruon with one axon and many dendrites attached to its soma  
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show a neuron with one axon and one dendrite attached to its soma  
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unipolar neuron   show
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show the bud at the end of a branch of an axon; forms synapses with another neuron; sends information to that neuron  
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show a chemical that is released by a terminal button; has an excitatory or inhibitory effect on another neuron  
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membrane   show
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show a structure in the central region of a cell, containing the nucleolus and chromosomes  
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nucleolus   show
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show a cytoplasmic structure, made of protein, that serves as the site of production of proteins translated from mRNA  
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show a strand of DNA, with associated proteins, found in the nucleus; carries genetic information  
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deoxyribonucleic acid (DNA)   show
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gene   show
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show a macromolecule that delivers genetic information concerning the synthesis of a protein from a portion of a chromosome to a ribosome  
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show a molecule that controls a chemical reaction, combining two substances or breaking a substance into two parts  
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show a form of RNA that does not encode for protein but has functions of its own  
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show the viscous, semiliquid substance contained in the interior of a cell  
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show an organelle that is responsible for extracting energy from nutrients  
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adenosine triphosphate (ATP)   show
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endoplasmic reticulum   show
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show the site of synthesis of lipids and provides channels for the segregation of molecules involved in various cellular processes.  
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Rough endoplasmic reticulum   show
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Golgi apparatus   show
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exocytosis   show
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show an organell surrounded by membrane; contains enzymes that break down waste products  
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cytoskeleton   show
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microtubules   show
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axoplasmic transport   show
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anterograde   show
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retrograde   show
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glia   show
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astrocyte   show
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phagocytosis   show
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show a type of glial cell in the CNS that forms myelin sheaths  
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myeline sheath   show
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node of Ranvier   show
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microglia   show
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show a cell in the PNS that is wrapped around a myelinated axon, providing one segment of its myelin sheath  
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blood-brain barrier (BBB)   show
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show a region of the medulla where the BBB is weak; poisons can be detected there and can initiate vomiting  
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show the electrical charge across a cell membrane; the difference in electrical potential inside and outside the cell  
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resting potential   show
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show reduction (toward zero) of the membrane potential of a cell from its normal resting potential  
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hyperpolarization   show
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action potential   show
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threshold of excitation   show
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diffusion   show
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show an aqueous solution of a material that ionizes--namely, a soluble acid, base, or salt  
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ion   show
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show the attractive force between atomic particles charged with opposite signs or the repulsive force between atomic particles charged with the same sign.  
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intracellular fluid   show
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show body fluids located outside of cells  
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sodium-potassium transporter   show
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show a specialized protein molecule that permits specific ions to enter or leave cells  
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voltage-dependent ion channel   show
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show the principle that once an action potential is triggered in an axon, it is propagated, without decrement, to the end of the fiber  
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show the principle that variations in the intensity of a stimulus or other information being transmitted in an axon are represented by variations in the rate at which that axon fires  
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saltatory conduction   show
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postsynaptic potential   show
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binding site   show
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show a chemical that binds with the binding site of a receptor  
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show a small bud on the surface of a dendrite, with which a terminal button of another neuron forms a synapse  
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show the membrane of a terminal button that lies adjacent to the postsynaptic membrane and through which the neurotransmitter is released  
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postsynaptic membrane   show
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synaptic cleft   show
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show a small, hollow, beadlike structure found in terminal buttons; contains molecules of a neurotransmitter  
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show a region of the interior of the presynaptic membrane of a synapse to which synaptic vesicles attach and release their neurotransmitter into the synaptic cleft  
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postsynaptic receptor   show
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neurotransmitter-dependent ion channel   show
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show a receptor that contains a binding site for a neurotransmitter and an ion channel that opens when a molecule of the neurotransmitter attaches to the binding site  
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show a receptor that contains a binding site for a neurotransmitter; activates an enzyme that begins a series of events that opens an ion channel elsewhere in the membrane of the cell when a molecule of the neurotransmitter attaches to the binding site  
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G protein   show
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second messenger   show
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show an excitatory depolarization of the postsynaptic membrane of a synapse caused by the liberation of a neurotransmitter by the terminal button  
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show an inhibitory hyperpolarization of the postsynaptic membrane of a synapse caused by the liberation of a neurotransmitter by the terminal button  
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reuptake   show
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show the destruction of a neurotransmitter by an enzyme after its release--for example the destruction of acetylcholine by acetylcholinesterase  
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acetylcholine (ACh)   show
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acetylcholinesterase (AChE)   show
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show the process by which inhibitory and exitatory postsynaptic potentials summate and control the rate of firing of a neuron  
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show a receptor molecule located on a neuron that responds to the neurotransmitter released by that neuron  
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show the action of a presynaptic terminal button in an axoaxonic synapse; reduces the amount of neurotransmitter released by the postsynaptic terminal button  
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presynaptic facilitation   show
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show a special juntion between cells that permits direct communication by means of electrical coupling  
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show a naturally secreted substance that acts like a neurotransmitter except that it is not restricted to the synaptic cleft but diffuses through the extracellular fluid  
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show a chain of amino acids joined together by peptide bonds. Most neuromodulators, and some hormones, consist of peptide molecules  
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show a chemical substance that is released by an endocrine gland that has effects on target cells in other organs  
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show a gland that liberates its secretions into the extracellular fluid around capillaries and hence into the bloodstream  
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show the type of cell that is directly affected by a hormone or other chemical signal  
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show a chemical of low molecular weight, derived from cholesterol. Steroid hormones affect their target cells by attaching to receptors found within the nucleus  
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drug effect   show
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sites of action   show
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pharmacokinetics   show
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show injection of a substance directly into a vein  
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show injection of a substance into the peritoneal cavity--the space that surrounds the stomach, intestines, liver, and other abdominal organs  
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intramuscular (IM) injection   show
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subcutaneous (SC) injection   show
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show administration of a substance into the mouth so that it is swallowed  
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show administration of a substance by placing it under the tongue  
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intrarectal administration   show
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inhalation   show
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topical administration   show
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show administration of a substance directly into the brain  
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show administration of a substance into one of the cerebral ventricles  
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show a graph of the magnitude of an effect of a drug as a function of the amount of drug administered  
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show the ratio between the dose that produces the desired effect in 50% of the animals and the dose that produces a toxic effect in 50% of the animals  
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affinity   show
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sensitization   show
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show the appearance of symptoms opposite to those produced by a drug when the drug is administered repeatedly and then suddenly no longer taken  
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show an inert substance that is given to an organism in lieu of a physiologically active drug; used experimentally to control for the effects of mere administration of a drug  
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antagonist   show
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show a drug that facilitates the effects of a particular neurotransmitter on the postsynaptic cell  
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show a drug that binds with and activates a receptor  
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show a drug that binds with a receptor but does not activat it; prevents the natural ligand from binding with the receptor  
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direct antagonist   show
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show binding of a drug to a site on a receptor; does not interfere with the binding site for the principal ligand  
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indirect antagonist   show
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indirect agonist   show
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presynaptic heteroceptor   show
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show a cofactor that supplies acetate for the synthesis of acetylcholine  
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show the enzyme that transfers the acetate ion from acetyl coenzyme A to choline, producing the neurotransmitter acetylcholine  
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show an acetylcholine antagonist; prevents release by terminal buttons  
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show a poison produced by the black widow spider that triggers the release of acetylcholine  
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neostigmine   show
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nicotinic receptor   show
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show a metabotropic acetylchiline receptor that is stimulated by muscarine and blocked by atropine  
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atropine   show
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show a drug that blocks nicotinic acetylcholine receptors  
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show a class of amines that includes indolamines, such as serotonin; and catecholamines, such as dopamine, norepinephrine, and epinephrine  
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show a class of amines that includes the neurotransmitters dopamine, norepinephrine, and epinephrine  
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show a neurotransmitter; one of the catecholamines  
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l-DOPA   show
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nigrostriatal system   show
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mesolimbic system   show
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show a system of dopaminergic neurons originating in the ventral tegmental area and terminating in the prefronal cortex  
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show a neurological disease characterized by tremors, rigidity of the limbs, poor balance, and difficulty in initiating movements; caused by degeneration of the nigrostriatal system  
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AMPT   show
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show a drug that interferes with the storage of monoamines in synaptic vesicles  
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apomorphine   show
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methylphenidate   show
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monoamine oxidase (MAO)   show
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deprenyl   show
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chlorpromazine   show
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norepinephrine   show
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epinephrine   show
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show a drug that inhibits the activity of the enzyme dopamine-B-hydroxylase and thus blocks the production of norepinephrine  
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show a drug that blocks the activity of MAO-A; acts as a noradrenergic agonist  
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locus coeruleus   show
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show an enlarged region along the length of an axon that contains synaptic vesicles and releases a neurotransmitter or neuromoculator  
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show a drug that blocks presynaptic noradrenergic (alpha 2) receptors and hence acts as an agonist, facilitating the synthesis and release of NE  
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serotonin (5-HT)   show
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show a drug that inhibits the activity of tryptophan hydroxylase and thus interferes with the synthesis of 5-HT  
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fluoxetine   show
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show a drug that stimulates the release of 5-HT  
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LSD   show
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MDMA   show
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histamine   show
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show an amino acid; the most important excitatory neurotransmitter in the brain  
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show a specialized ionotropic glutamate receptor that controls a calcium channel that is normally blocked by Mg2+ ions; has several ohter binding sites  
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AMPA receptor   show
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kainate receptor   show
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metabotropic glutamate receptor   show
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show a drug that blocks the glutamate binding site on NMDA receptors  
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show phencyclidine; a drug that binds with the PCP binding site of the NMDA receptor and serves as an indirect antagonist  
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GABA   show
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show a drug that inhibits the activity of GAD and thus blocks the synthesis of GABA  
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show glutamic acid decarboxylase, an enzyme that produces GABA by removing a carboxyl group from glutamic acid  
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muscimol   show
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show a direct antagonist for the GABA binding site on the GABA-A receptor  
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benzodiazepine   show
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show an anxiety-reducing effect  
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glycine   show
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strychnine   show
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show the first cannabinoid to be discovered and probably the most important one  
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endogenous opioid   show
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show one of the endogenous opioids  
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naloxone   show
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show a lipid; an endogenous ligand for cannabinoid receptors, which also bind with THC, the active ingredient in Marijuana  
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show the active ingredient in marijuana; activates CB-1 receptors in the brain  
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anandamide   show
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show fatty acid amide hydrolase, the enzyme that destroys anandamide after it is brought back into the cell by anandamide transporters  
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show a drug that blocks CB-1 receptors  
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show a drug that inhibits FAAH; prevents the breakdown of anandamide  
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show a drug that inhibits the reuptake of anandamide  
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show a nucleoside; a combination of ribose and adenine; serves as a neuromodulator in the brain  
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show a drug that blocks adenosine receptors  
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show a gas produced by cells in the nervous system; used as a means of communication between cells  
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show the enzyme responsible for the production of nitric oxide  
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electromyogram (EMG)   show
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show an electrical potential from the eyes, recorded by means of electrodes placed on the skin around them; detects eye movements.  
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alpha activity   show
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beta activity   show
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show EEG activity of 3.5 - 7.5 Hz that occurs intermittently during early stages of slow-wave sleep and REM sleep.  
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delta activity   show
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slow-wave sleep   show
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show a period of inhibition during a slow oscillation during slow-wave sleep; neurons in the neocortex are silent and resting.  
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up state   show
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REM sleep   show
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show all stages of sleep except REM sleep  
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sleep apnea   show
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narcolepsy   show
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sleep attack   show
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show a symptom of narcolepsy; complete paralysis that occurs during waking  
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sleep paralysis   show
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show a symptom of narcolepsy; vivid dreams that occur just before a person falls asleep; accompanied by sleep paralysis  
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show a peptide, aslo known as hypocretin, produced by neurons whose cell bodies are located in the hypothalamus; their destruction causes narcolepsy  
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REM sleep behavior disorder   show
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sleep-related eating disorder   show
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fatal familial insomnia   show
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show the increased frequency or intensity of a phenomenon after it has been temporarily suppressed; for example, the increase in REM sleep seen after a period of REM sleep deprivation  
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show a neuromodulator that is released by neurons engaging in high levels of metabolic activity; may play a primary role in the initiation of sleep  
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show a dark-colored group of noradrenergic cell bodies located in the pons near the rostral end of the floor of the fourth ventricle; involved in arousal and vigilance  
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raphe nuclei   show
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show a neurotransmitter synthesized from the amino acid histidine; plays an important role in maintenance of wakefulness and arousal  
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tuberomammillary necleus (TMN)   show
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sublaterodorsal nucleus (SLD)   show
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ventrolateral periaqueductal gray matter (vlPAG)   show
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circadian rhythm   show
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zeitgeber   show
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show A nucleus situated atop the optic chiasm in the hypothalamus. it contains a biological clock that is responsible for organizing many of the body's circadian rhythms, and was discovered after the nocturnal behaviors of rats were disrupted.  
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melanopsin   show
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advanced sleep phase syndrome   show
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show a 4-hour delay in rhythms of sleep and temperature cycles, possibly caused by a mutation of a gene (per3) involved in the rhythmicity of neurons of the SCN.  
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show a gland attached to the dorsal tectum; produces melatonin and plays a role in circadian and seasonal rhythms  
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show a hormone secreted during the night by the pineal body; plays a role in circadian and seasonal rhythms  
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sexually dimorphic behavior   show
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show a mature reproductive cell; a sperm or ovum  
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show the X and Y chromosomes, which determine an organism's gender. ormally, XX individuals are female, and XY individuals are male  
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gonad   show
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Sry   show
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organizational effect (of hormones)   show
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show the effect of a hormone that occurs in the fully developed organism; may depend on the organism's prior exposure to the organizational effects of hormones  
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Mullarian system   show
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show the embryonic precursors of the male internal sex organs. Develops into the epididymis, vas deferens, and seminal vesicles.  
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show a peptide secreted by the fetal testes that inhibits the development of the mullerian system, which would otherwise become the female internal sex organs.  
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show an effect of a hormone present early in development that reduces or prevents the later development of anatomical or behavioral characteristics typical of females  
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androgen   show
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masculinizing effect   show
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testosterone   show
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show an androgen, produced from testosterone through the action of the enzyme 5(alpha) reductase  
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show a condition caused by a congenital lack of functioning androgen receptors; in a person with XY sex chromosomes, causes the development of a female with testes but no internal sex organs  
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persistent mullerian duct syndrome   show
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Turner's syndrome   show
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show include gonads, internal sex organs, and external genitalia  
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secondary sex characteristics   show
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show a hypothalamic hormone that stimulates the anterior pituitary gland to secrete gonadotropic hormone.  
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gonadotropic hormone   show
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follicle-stimulating hormone (FSH)   show
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show a hormone of the anterior pituitary gland that causes ovulation and development of the ovarian follicle into a corpus luteum.  
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kisspeptin   show
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estradiol   show
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estrogen   show
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menstrual cycle   show
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estrous cycle   show
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show a cluster of epithelial cells surrounding an oocyte, which develops into an ovum  
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show a cluster of cells that develops from the ovarian follicle after ovulation; secretes estradiol and progesterone  
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progesterone   show
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refractory period   show
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coolidge effect   show
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oxytocin   show
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lordosis   show
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pheromone   show
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Lee-Boot effect   show
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whitten effect   show
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show the earlier onset of puberty seen in female animals that are housed with males; caused by a pheromone in the males' urine; first observed in mice  
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bruce effect   show
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show a sensory organ that detects the presence of certain chemicals, especially when a liquid is actively sniffed; mediates the effects of some pheromones  
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show a neural structure located in the main olfactory bulb that receives information from the vomeronasal organ  
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show a nucleus that receives olfactory information fro the olfactory bulb and accessory olfactory bulb; involved in the effects of odors and pheromones on reproductive behavior  
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Created by: turnfam3
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