Comprehensive Pharm 3
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| show | DUMBBELSS Diarrhea Urination Miosis Bradycardia Bronchospasm Excitation of skel muscle Lacrimation Sweating Salivation
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| show | atropine + pralidoxime
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| what is pralidoxime | show 🗑
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| MOA of epi in tx of glaucoma | show 🗑
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| MOA brimonidine in tx of glaucoma | show 🗑
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| show | decreases aqueous humor secretion
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| MOA acetazolamide in tx of glaucoma | show 🗑
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| show | increased outflow of aqueous humor
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| which drug should be used in a glaucoma emergency | show 🗑
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| show | PGF-alpha, increases outflow of aqueous humor
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| show | beta-blockers brimonidine acetazolamide
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| which glaucoma drugs increase outflow of aqueous humor? | show 🗑
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| show | muscarinic antagonist
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| toxicity of atropine | show 🗑
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| show | down down up (reflex) up (reflex) down down
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| show | up down down down up down
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| show | no effect, or down down little, no effect down little/no effect down a lot!
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| MOA CCBs | show 🗑
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| show | nifedipine > diltiazem > verapemil
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| in decreasign effeect, which CCBs have most effect on heart? | show 🗑
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| show | nifedipine
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| toxicity of CCBs | show 🗑
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| which CCB is most similar to nitrates in effect? | show 🗑
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| which CCB is most similar to b-blockers in effect? | show 🗑
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| MOA statins? | show 🗑
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| MOA niacin | show 🗑
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| show | binds cholesterol in the gut so they can't get to the hepatocytes
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| show | cholesterol absorption blocker so, prevents cholesterol from entering hepatocytes from gut
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| show | increases action of lipoprotein lipase, encouraging the breakdown of VLDL --> LDL also decreases hepatic synthesis and secretion of VLDL increases HDL by decreasing TG (results from decreased VLDL) --> decresaed exchange of cholestreryl esters from HDL
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| which cholesterol agents affect endogenous production of cholesterol? | show 🗑
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| which cholesterol agents affect absorption of exogenous cholesterol | show 🗑
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| show | down A LOT up down
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| effects of niacin on LDL HDL TGs | show 🗑
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| show | down a lot (not as much as statins) none slightly UP
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| show | down a lot (not as much as statins) none none
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| effects of fibrates on: LDL HDL TGs | show 🗑
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| what 2 cholesterol drugs, if taken concurrently, will cause rhabdomyolysis | show 🗑
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| show | your lft's are not SEF (safe) statins ezetimibe fibrates
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| show | bile acid resins
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| show | anti-dig Fab fragment s slowly normalize K lidocaine cardiac pacer
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| MOA of class I anti-arrhythmics class II? class III? class Iv? | show 🗑
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| show | Quinidine Amiodarone Procainamide Disopyramide
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| which drugs are in the class Ib anti-arrhythmics? | show 🗑
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| which drugs are in the class Ic anti-arrythmics? | show 🗑
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| show | increased AP duration increased ERP increased QT interval
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| uses for class IA anti-arrhythmics | show 🗑
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| MOA for class IB anti-arrhythmics | show 🗑
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| use for class IB anti-arrhythmics | show 🗑
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| show | no effect on AP
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| show | VT --> FV inretractable SVT LAST resort
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| toxicity of quinidine | show 🗑
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| toxiciyt of procainamide | show 🗑
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| show | local anesthetic CNS stimulation/depression CV depression
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| show | pro-arrhythmic (esp post-MI) prolongs refractory period
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| show | all are equal
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| show | a1 = a2 > b1
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| show | B1=b2
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| show | d1 = d2 > B > a
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| show | b1 > b2
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| receptor selectivity for phenylephrine | show 🗑
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| receptor selectivity for albuterol | show 🗑
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| receptor selectivity for terbutaline | show 🗑
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