Promethazine
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| Promethazine GENERIC NAME | Promethazine
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| Promethazine BRAND NAME | Phenergan
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| Promethazine CLASS | Antiemetics, antihistamine, sedative/hypnotics
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| Promethazine MECHANISM OF ACTION | Blocks the effects of histamine. Alters the effects of dopamine in the CNS. Possesses significant anticholinergic activity.
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| Promethazine INDICATIONS | Treatment of various allergic conditions and motion sickness. Treatment and prevention of N/V
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| Promethazine CONTRAINDICATIONS | Narrow-angle glaucoma, comatose patients, children less then 2yr.
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| Promethazine ADVERSE REACTIONS | confusion,disorientation, sedation, dizziness, insomnia, nervousness, Blurred vision, diplopia
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| Promethazine INCOMPATABILITIES/DRUG INTERACTIONS | Potentiates other CNS depressants, Additive anticholinergic effects with other drugs possessing anticholinergic properties.
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| Promethazine DOSE/ROUTE, Adult antihistamine IV | 25mg, may repeat in 2hr.
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| Promethazine Adult antiemetic IV | 10-25mg Q4hr as needed.
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| Promethazine Peds antihistamine IV | Not recommended
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| Promethazine Peds antiemetic IV | 0.25-0.5 mg/kg q 4-6 hours
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| Promethazine ONSET OF ACTION | IV 3-5 minutes
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| Promethazine PEAK EFFECTS | Unknown
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| Promethazine DURATION OF ACTION | 4-12 hours
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| Promethazine AZ DRUG BOX SUPPLY RANGE | Not carried
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