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Module 4 Antibiotic Names and Classes from Objectives

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Question
Answer
Sulfamethoxazole   show
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show Sulfonamide combo, bacteriostatic, UTI and otitis media  
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show Penicillins, bactericidal, weaken cell wall, strep pneumonia, meningitis, endocarditis.  
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Nafcillin   show
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show Penicillins, bactericidal, weaken cell wall, strep pneumonia, meningitis, endocarditis.  
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Ampicillin/Sulbactam (Unasyn)   show
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show Penicillins, bactericidal, weaken cell wall, strep pneumonia, meningitis, endocarditis.  
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show Penicillins, bactericidal, weaken cell wall, strep pneumonia, meningitis, endocarditis.  
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show Penicillins, bactericidal, weaken cell wall, strep pneumonia, meningitis, endocarditis.  
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show Cephalosporin 1st generation, bactericidal, weaken cell wall, surgical prophylaxis. Destroyed by beta-lactamases (cephalosporinases)  
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show Cephalosporin 2nd generation, bactericidal, weaken cell wall, surgical prophylaxis (1st Generation used more often). Less sensitive to destruction by beta-lactamases (cephalosporinases) better activity against gram - than 1st generation,  
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show Cephalosporin 4th generation, bactericidal, weaken cell wall, CSF infection. Highly resistant to destruction by beta-lactamases (cephalosporinases).Healthcare and hospital associated pneumonias.  
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show Carbapenems, bactericidal, weaken cell wall. Bone, joint, skin, and soft tissue (complicated body cavity infections).  
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show Vancomycin, bactericidal, cell wall destroyed, MRSA and pts with penicillin allergies. ***Watch for renal damage.  
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Doxycycline   show
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Erythromycin   show
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Azithromycin   show
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Clarithromycin   show
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show ketolides, bateriostatic and can be bactericidal, inhibit protein synthesis. Mild to moderate upper respiratory infections.  
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ketolide (telethromycin)   show
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Clindamycin (cleocin)   show
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show Oxazolidinones. Inhibits protein synthesis. VRE and MRSA (limiting to those will help delay emergence of resistance)  
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show Primarily bacteriostatic (can also be bactericidal against specific bugs). Used judiciously when other antibiotics don't work. Often used with other abx. Penicillin resistant bacterial meningitis and VRE. Gray's syndrome in infants and children.  
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Gentamycin   show
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Amikacin   show
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show Aminoglycosides, bactericidal, inhibits protein synthesis. psuedomonas and E-coli.  
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show Flouroquinolones, inhibit bacterial synthesis of DNA and RNA or disrupt DNA function. Cellulitis, kidney infection, UTI, and Anthrax.  
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Metronidazole (Flagyl)   show
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Rifampin (Rifacin)   show
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show Monobactam, bacteriocidal, inhibits protein synthesis. Only active against gram negative (E Coli, Klebsiella, etc)  
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show Bactericidal, weakens cell wall, single dose therapy for uncomplicated UTI in women.  
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Tigecycline    show
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Dalfopristin/Quinupristin    show
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show Inhibits protein synthesis. Currently topical application and is highly resistant to becoming drug resistant. (long hx in vet medicine without resistance)  
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show Bacteriostatic at low concentrations and bacteriostatic at high concentrations. Used topically, effective against gram positive bacteria. Treats impetigo.  
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show Fluoroquinolones, inhibit bacterial synthesis of DNA and RNA or disrupt DNA function. Pneumonia, Kidney infection, prostatitis. Watch for CNS  
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show Cyclic lipopeptides. Bactericidal. Nearly all gram + bacteria including MRSA.  
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Ceftriaxone (Rocephin)   show
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***5th generation Cephalosporin   show
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