Pediatrics
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__% of infants develop jaundice in the 1st week | show 🗑
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show | Physiologic jaundice
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__ fed babies are at higher risk for physiologic jaundice | show 🗑
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Jaundice with bilirubin >5mg/dL | show 🗑
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What is the bodily progression of jaundice | show 🗑
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show | biliary atresia
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Unconjugated hyperbilirubinemia that results from increase in RBC destruction (antibody mediated hemolysis) is Coombs: | show 🗑
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Non-immune hemolysis is Coombs: | show 🗑
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show | Unconjugated bilirubin in skin is converted to water soluble isomers that are excreted without conjugation
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Risks for physiologic jaundice | show 🗑
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show | Increased RBC destruction due to antibody-mediated hemolysis (ABO or Rh incompatibility). Nonimmune (hereditary spherocytosis, G6PD, cephalohematoma, polycythemia, ileus ).
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Pathologic unconjugated bilirubinemia: causes related to decreased conjugation rate | show 🗑
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show | Conjugated bilirubin
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show | indirect/unconjugated bili
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Water-soluble; placenta is impermeable to: | show 🗑
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Serious, rare, permanent deficiency of glucuronosyltransferase that results in severe indirect hyperbilirubinemia | show 🗑
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show | Breast milk jaundice
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show | Pathologic; probably direct bilirubinemia (DBil >2 or >20% of TBil)
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show | 16-18 mg/dL
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show | pathologic
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Jaundice involving the face: total serum bili is approximately: | show 🗑
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show | 15 mg/dL
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Jaundice involving the feet: total serum bili is approximately: | show 🗑
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