Chapters 4-5
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List the three conditions that must exist for the total body syndrome to occur. | show 🗑
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Explain the LD 50/30 by defining and listing the dose for humans in comparison to goldfish. | show 🗑
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show | Humans: 250-300 rads.
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show | 100-1,000 R. Damage to bone marrow by reduction in red blood cells, white blood cells and platelets.
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show | 600-10,000 R. Damage to GI tract and bone marrow includes depletion of villi cells and dehydration and electrolyte imbalance.
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Central nervous system (CNS) state the dose needed to exhibit symptoms: | show 🗑
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show | Nausea, vomiting, diarrhea.
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show | This stage appears to have no symptoms when in reality changes are taking place that will either lead to recovery or death.
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show | After the latent stage the subject will become noticeable ill, showing signs and symptoms reflecting the organ system that was damaged.
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Discuss the events of the following stages of the acute radiation syndrome: 4th stage: | show 🗑
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show | Depression of all blood cell counts.
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show | Reduction in red blood cell counts.
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Define Crypts of Lieberkuhn: | show 🗑
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Define Edema: | show 🗑
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Define Vasculitis: | show 🗑
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show | Inflammation of the membranes of the spinal cord and brain.
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show | Shrinking.
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Define Desquamation: | show 🗑
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show | Tissue death.
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Define Alopecia: | show 🗑
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show | 600 rad, that follows a nonlinear, threshold dose-response relationship.
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Identify the approximate radiation doses need to produce Temporary sterility: | show 🗑
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Identify the approximate radiation doses need to produce permanent sterility: | show 🗑
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Identify the approximate radiation doses need to restrain menstruation: | show 🗑
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show | Bone marrow, circulating blood, lymph nodes, spleen and thymus gland.
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Describe the location and function of red bone marrow: | show 🗑
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Describe the location and function of yellow bone marrow: | show 🗑
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show | aberrations, lesions, or anomalies.
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Describe the purpose of a karotype. | show 🗑
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Discuss the difference between somatic and genetic mutations. | show 🗑
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List several groups of individuals that have been studied to determine long term effects of radiation exposure. | show 🗑
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show | Leukemia, skin carcinoma, thyroid cancer, breast cancer, osteoscarcoma and lung cancer.
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Define GSD: | show 🗑
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show | The dose of radiation required per generation to double the spontaneous mutation rate.
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show | Total dose, rate of dose, quality of radiation, stage of development.
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show | Prenatal or neonatal death, congenital abnormalities, growth impairment, reduced intelligence, genetic abnormalities, cancer induction.
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show | occur randomly in nature. Aka, statisical response in which the probability of occurence increases with dose.
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show | Deterministic.
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show | The theory that ionizing radiation is benign at low levels of exposure, and that doses at the level of natural background radiation can be benificial.
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show | erythrocytes, myelocytes, megakaryocytes.
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