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biological psycholo

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biological psychology   the study of the bioloical bases of psychological processes and behaviors.  
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neuroscience   the study of the nervous system.  
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behavioral neuroscience   the field of study concerned with the ways in which nervous system activity manifests in behavior.  
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conserved   In the context of evolution, referring to a trait that is passed on from a common ancestor to 2 or more decendant species  
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ontogeny   the process by which an individual changes in the course of it's life time - that is, grows up and grows old.  
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neuron   also called the nerve cell, the basic unit of the nervous system.  
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somatic intervention   an approach to finding relations between body variables and behavioral variables that involves manipulating body structure or function and looking for resultant changes in behavior  
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independant variable   the factor that is manipulated by the experimenter.  
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dependant variable   the factor that an experimenter measures to monitor a change in response to changes in an independant variable.  
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behavioral intervention   an approach to finding relations between body variables and behavioral variables that involves invtervening in the behavior of an organism and looking for resultant changes in body structure or function.  
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correlation   the covariation of two measures.  
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neural plasticity   also called neuroplasticity, the ability of the nervous system to change in response to experience or the environment.  
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dualism   the notion, promoted by Descartes, that the mind is subject only to spiritual interactions, while the body is subject only to material interactions.  
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phrenology   the belief that bumps on the skull reflect enlargements of brain regions responsible for certain behavioral faculties.  
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conciousness   the state of awareness of one's own existance and experience.`  
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histology   the study of tissue structure.  
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gross neuroanatomy   anatomical features of the nervous system that are apparent to the naked eye.  
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neurophysiology   the study of the life process of neurons.  
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chemical neuroanatomy   the distribution of key chemicals, such as transmitters and enzymes, within the structure of the nervous system.  
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neuropharmacology   also called psychpharmacology, the study of the effects of drugs on the nervous system and behavior.  
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neuron or nerve cell   the basic unit of the nervous system, each composed of a cell body, receptive extension(s) (dendrites), and a transmitting extension (axon).  
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neuron doctrine   the hypothesis that the brain is composed of seperate cells that are distinct structurally, metabolically and functionally.  
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synapse   a cellular location at which information is transmitted from one neuron to another.  
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glial cells   also called glia or neuroglia, nonneural brain cells that provide structural, nutritional, and other types of support to the brain.  
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mitocondrion   a cellular organelle that provides metabolic energy for the cell's processes.  
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cell nucleus   the spherical central structure of a cell that contains the chromosomes.  
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ribosomes   structures in the cell body where genetic information is translated (protiens are produced).  
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dendrite   one of the extensions of the cell body that are the receptice surfaces of the neuron.  
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input zone   the part of the neuron that recieves information, from other neurons or from specialized sensory structures. usually corresponds to the cell's dendrites.  
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cell body or soma   the region of a neuron that is defined by the presence of the cell nucleus.  
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integration zone   the part of the neuron that initiates nerve activity if the sum of all inhibitory and excitatory post synaptic potentials exceeds a threshold value. Usually corresponds to the neuron's axon hillock.  
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axon   a single extension from the nerve cell that carries nerve impulses from the cell body to other neurons.  
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conduction zone   the part of the neuron over which the nerve's electrical signal may be actively propageted. Usually corresponds to the cell's axon.  
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axon terminal   the end of an axon or axon collateral, which forms a synapse on a neuron or other target.  
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output zone   the part of a neuron, usually corresponding to the axon terminals, at which the cell's electrical activity is conveyed to another cell.  
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multipolar region   a nerve cell that has many dendrites and a single axon.  
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bipolar neuron   a nerve cell that has a single dendrite at one end and a single ax`on at the other end.  
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monoploar neuron   a nerve with a single brance that leaves the cell body and then extends in 2 directions: one end is the receptive pole, and the other end the output zone.  
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motoneuron   also called a motor neuron, a nerve cell in the spinal cord that transmits motor messages from the spinal cord to muscles.  
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sensory neuron   a neuron that is directly affected by changes in the environment, such as light, odor or touch.  
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interneuron   a neuron that is neither a sensory neuron nor a motoneuron; it receives input from and sends output to other neurons.  
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astrocyte   a star-shaped glial cell with numerous processes (extensions) that run in all directions.  
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Golgi stain   a hitorical stain that fills a small proportion of neurons with a dark silver-based precipitate.  
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Nissl Stain   a historical stain that outlines all cell bodies because the dyes are attracted to RNA, which encircles the nucleus.  
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autoradiography   a histological technique that shows the distribution of radioactive chemicals in tissues.  
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immunocytochemistry (ICC)   a method for detecting a particular protien in tissues in which 1) an antibody recognizes and binds to the protien and 2) chemical methods are then used to leave a visible reaction product around each antibody.  
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in situ hybridization   a method for detection particular RNA transcripts in tissue sections by providing a neucletide probe that is complementary to, and wil therefore hybridize with, the transcript of interest.  
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immediate early genes (IEGS   a class of genes that show rapid but transient increases in expression in cells that have become activated.  
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c-fos   an immediate early gene commonly used to identify activated neurons.  
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horseradish peroxidase (HRP)   an enzyme found in horseradish and other plants that is used to determine the cells of origin of a particular set of axons.  
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microglial cells   also called microglia, extremely small glial cells that remove cellular debris from injured or dead cells.  
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myelin   the fatty isulation around an axon, formed by accessory cells, that improves the speed of conduction of nerve impulses.  
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myelination   the process of myelin formation.  
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node of Ranvier   a gap between successive segments of the myelin sheath where axon membrane is exposed.  
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multiple sclerosis   literally meaning "many scars"; a disorder characterized by widespread degeneration of myelin.  
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oligodendrocyte   a type of glial cell that is commonly associated with nerve cell bodies.  
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Schwann cell   the accessory cell that forms myelin in the peripheral nervous system.  
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edema   the swelling of tissue, especially in the brain, in response to injury.  
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arborization   the elaborate branching of the dendrites of some neurons.  
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presynaptic   referring to the region of a synaps that releases neurotransmitter.  
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postsynaptic   referring to the region of a synapse that recieves and responds to neurotransmitter.  
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presynaptic membrane   the specialized membrane of the axon terminal of the neuron that transmits information by releasing the neurotransmitter.  
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postsynaptic membrane   the specialized membrane on the surface of the cell that recieves information from a presynaptic neuron.  
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synaptic cleft   the space between the presynaptic and postsynaptic elements  
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synaptic vesicle   a small, spherical structure that contains molecules of synaptic transmitter.  
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neurotransmitter   also a synaptic transmitter, chemical transmitter or transmitter, the chemical released from the presynaptic axon terminal, that serves as the basis of communication between neurons.  
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receptor   also called a receptor molecule, a protien that captures and reacts to molecules of a transmitter or hormone.  
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dendritic spin   an outgrowth along the dendrite of a neuron.  
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neural plasticity   also called neuroplasticity, the ability of the nervous system to change in response to experience or the environment  
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axon hillock   a cone-shaped area from which the axon originates out of the cell body.  
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axon collateral   a brance of an axon from a single neuron.  
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axonal transport   the transportation of materials from the neuron cell body to distant regions in the dendrites and axons, and from the axon terminals to the cell body.  
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peripheral nervous system   the portion of the nervous system that includes all the nerves and neurons outside the brain and the spinal cord.  
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central nervous system (CNS)   the portion of the nervous system that includes the brain and the spinal cord.  
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nerve   a collection of axons bundled together outside the central nervous system.  
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cranial nerve   a nerve that is connected directly to the brain.  
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spinal nerve   also called somatic nerve, a nerve that emerges from the spinal cord.  
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autonomic nervous system   the part of the peripheral nervous system that supplies neural connections to glands and to smoothe muscles of internal organs.  
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dorsal root   the brace if a spinal nerve, entering the dorsal horn of the spinal cord, that carries sensory information from the peripheral nervous system to the spinal cord.  
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venral root   the brance of a spinal nerve, arising from the ventral horn of the spinal cord, that carries motor messages from the spinal cord to the peripheral nervous system.  
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cervical   referring to the topmost 8 segments below the spinal cord, in the neck region.  
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thoracic   referring to the 12 spinal segments below the cervical (neck) portion of the spinal cord, corresponding to the chest.  
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lumbar   referring to the 5 spinal segments that make up the upper part of the lower back.  
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sacral   referring to the 5 spinal segments that make up the lower part of the lower back  
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coccygeal   referring to th lowest spinal vertebra (also known as the tailbone).  
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autonomic ganglia   collections of nerve cell bodies, belonging to the autonomic division of the peripheral nervous system, that are found in various locations and innervate the major organs.  
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preganglionic   "before the ganglion", referring to the neurons in the autonomic division that run from the autonomic ganglia to various targets in the body.  
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postganglionic   "after the ganglion", referrin to neurons in the autonomic nervous system that run from the central nervous system to the autonomic ganglia.  
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sympathetic nervous system   one of two systems that compose the autonomic nervous system. arises from the thoracic and lumbar spinal cord.  
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sympathetic chain   a chain of ganglia that runs along each side of the spinal column; part of the sympathetic nervous system.  
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parasympathetic nervous system   one of two systems that compose the autonomic nervous system. arises from both the cranial nerves and the sacral spinal cord.  
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enteric nervous system   a extensive meshlike system of neurons that governs the functon of th the gut.  
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cerebral hemispheres   the right and left halves of the forebrain.  
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gyrus   a ridged or raised portion of a convoluted brain surface.  
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sulcus   a furrow of a convoluted brain surface.  
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frontal lobe   th most anterior portion of the cerebral cortex.  
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parietal lobes   large regions of cortex lying between the front and occipital lobes of each cerebral hemisphere.  
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temporal lobes   large lateral cortical regions of each cerebral hemispheres continuous of the parietal lobes posteriorly, and seperated from the frontal lobe by the sylvian fissure.  
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occipital lobes   large regions of cortex covering much of the posterior part of eache cerebral hemisphere.  
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Sylvian fissure   a deep fissure that demarcates the temperal lobe.  
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central sulcus   a fissure that divides the frontal lobe from the parietal lobe.  
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cerebral cortex   the outer covering of the cerebral hemispheres.  
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postcentral gyrus   the strip of parietal cortex, just behind the central sulcus that recieves somatosensory information from the entire body.  
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precentral gyrus   the strip of frontal cortex, just in front of the central sulcus, that is crucial to motor control.  
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corpus collosum   the main band of axons that connects the two cerebral hemispheres.  
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white matter   a shiny layer underneath the cortex that consists largely of axons with white myelin sheaths.  
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grey matter   areas of the brain that are dominated by cell bodies and are devoid of myelin.  
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neural tube   an embryonic structure with subdivisions that correspond to the future forebrain, midbrain and hindbrain.  
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forebrain   also called the prosencephalon, the frontal division of the neural tube, containing the cerebral hemispheres, the thalamus, and the hypothalamus.  
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midbrain   also called the mesencephalon, the middle division of the brain.  
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hindbrain   also called the rhombcephalon, the rear division of the brain, which, in the mature vertabrate, contains the cerebellum, pons and medulla.  
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telencephalon   the fronal subdivision of the forebrain that includes the cerebral hemispheres when fully developed.  
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diencephalon   the posterior part of the forebrain, including the thalimus and the hypothalimus.  
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metencephaon   a subdivision of the hindbran that includes the cerebellum and the pons.  
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cerebellum   a structure located at the back of the brain, dorsal to the pons, that is involved in the central regulation of movement.  
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pons   a portion of the metencephalon.  
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myelencephalon or medulla   the caudal part of the hindbrain.  
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brainstem   the region of the brain that consists of the midbrain, the pons and the medulla.  
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nucleus   here, an anatomical collection of neurons within the central nervous system.  
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tract   a bundle of axons found within the central nervous system.  
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basal ganglia   a group of forebrain nuclei (caudate nucleus, globus pallidus and putamen)found deep within the cerebral hemispheres.  
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caudate nucleus   one of the basal ganglia; it has a long extension or tail.  
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putamen   one of the basal ganglia.  
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globus palladis   one of the basal ganglia.  
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substantia nigra   a brainstem structure in humans thatis related to the basal ganglia and named for it's dark pigmentation.  
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limbic system   a losely defined, widespread group of brain nuclei that innervate eachother to form a network.  
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amygdala   a group of nuclei in the medial anterior part of the temperal lobe.  
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hippocampus   a medial temporal lobe structure that is thought to be important for learning and memory.  
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fornix   a fiber tract that extends from the hippocampus to the mammillary body.  
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cingulate gyrus   a critical portion of the lymbic system, found in the frontal and parietal midline.  
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olfactory bulb   an anterior basal structure that recieves olfactory (smell) imputs from the nasal cavaties.  
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mammilllary body   one of the pair of nuclei at the base of the brain.  
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thalamus   the brain regions that surround the third ventricle.  
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hypothalamus   part of the diencephalon, lying ventral to the thalamus.  
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superior colliculi   paired structures on the dorsal surface of the midbrain, rostral to the inferior colliculi that recieve visual information.  
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inferior colliculi   paired structures on the dorsal surface of the midbrain, caudal to the superior colliculi, that recieve auditory information.  
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tectum   the dorsal portion of the midbrain, including the inferior and superior colliculi.  
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red nucleus   a brainstem structure related to motor control.  
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reticular fromation   an extensive region of the brainstem (extending from the medulla throught the thalamus)that is involved in arousal.  
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Purkinje Cell   a type of large nerve cell in the cerebellar cortex.  
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granule cell   a type of small nerve cell.  
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parallel fiber   on of the axons of the granule cells that form the outermost layer of the cerebellar cortex.  
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isocortex (or cortex)   cerebral cortex that is made up of 6 distinct layers (formerly referred to as the neocortex).  
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allocortex   brain tissue with 3 layers or unlayered organization.  
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pyramidal cell   a type of large nerve cell that has a roughly pyramidal-shaped cell body; found in the cerebral cortex.  
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apical dendrite   the dendrite that extends from a pyramidal cell to the outermost surface of the cortex.  
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basal dendrite   one of several dendrites on a pyramidal cell that extend horizontally from the cell body.  
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cortical column   one of the vertical columsn that constitute the basic organization of the isocortex.  
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meninges   the 3 protective sheets of tissue-dura mater, pia matter, and arachnoid-that surround the brain and spinal cord.  
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dura mater   the outermost of the 3 meninges that surround the brain and spinal cord.  
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pia mater   the inntermost of the 3 meninges that surround the brain and the spinal cord.  
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arachnoid   the thin covering(one of the 3 meninges) of the brain that lies between the dura mater and pia mater.  
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cerebrospinal fluid (CSF)   th fluid that fills the cerebral ventricles.  
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meningitis   an acut inflamation of the meninges, usually caused by a viral or bacterial infection.  
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ventricular system   a system of fluid filled cavities inside the brain.  
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lateral ventricle   a complexly shaped lateral portion of the ventricular system within each hemisphere of the brain.  
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choroid plexus   a highly vascular portion of the lining of the ventricles that secretes cerebrospinal fluid.  
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third ventricle   the midline ventricle that conducts cerebrospinal fluid from the lateral ventricles to the 4th ventricle.  
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fourth ventricle   the passageway within the pons that recieves cerebrospinal fluid from the 3rd ventricle and releases it to surround the brain and spinal cord.  
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carotid arteries   the major arteries that ascend the left and right sides of the neck to the brain.  
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anterior cerebral arteries   two large arteries, arising frim the internal carotids, that provide blood to the anterior poles and medial surfaces of the cerebral hemispheres.  
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middle cerebral arteries   two large arteries, arising frm the internal carotids, that provide blood to most of the lateral surfaces of the cerebral hemispheres.  
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vertebral arteries   arteries that ascend the vertabrae, enter the base of the scull, and jointogether to form the basilar artery.  
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basilar artery   an artery formed by the fusion of the bertebral arteris, that supples blood to the brainstem nd to posterior portions of the cerebral hemispheres.  
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posterior cerebral arteries   two large arteries, arising from the basilar artiery, that provide blood to the branstem and to posterior aspects of the cerebral hemispheres, cerebellum and brainstem.  
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circle of Willis   a structureat the base of the brain that is formed by the joining of carotid and basilar arteries.  
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stroke   damage to a region of the brain tissue that results from blockage or rupture of vessels that supply blood to that region.  
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blood-brain barrier   the mechanisms that make the movement of substances from capillaries into brain cells more difficult than exchanges in other body organs.  
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angiogram   a specialized x-ray image of thehad, taked shortly after the cerebral blood vessels hae ben filled with a radiopaque dye by means of a catheter.  
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computerized axial tomography (CAT or CT)   a oninvasive technique for examining brain structure in humans through computer analysis of X-ray absorption at several positions around the head  
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magnetic resonance imaging (MRI)   a noninvasive technique that uses magnetic energy to generate images that reveal some structural details in the living brain.  
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position emission tomography (PET)   a technique for examining brain function by combining tomography with injections of radioactive substances used by the brain.  
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functional MRI (fMRI)   magnetic resonance imaging that deects changes in blood flow and therefore identifies regions of the brain that are particularly active during a given task.  
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optical imaging   a method for visualizing brain activity in which near-infared light is passed through the scalp and scull.  
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transcranial magnetic stimulation (TMS)   localized, noninvasive stimulation of cortical neurons through the application of strong magnetic fields.  
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magnettoencephalography (MEG)   a passive and noninvasive functional brainimaging technique that measures the tiny magnetic fields produced by active neurons, in order to identify regions of the brain that are particularly active during a given task.  
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ion   an atom or molecule that has aquired an electrical charge by gaining or losing one or more electrons.  
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anion   a negatively charged ion, such as a protien or chloride ion.  
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cation   a positively charged ion, suc as a potassium or sodium ion.  
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intracellular fluid   also called cytoplasm, the watery solution found within cells.  
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extracellular fluid   the fluid in the spaces between cells (interstitial fluid) and in the vascular system.  
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