blood
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name the 5 functions of blood | show 🗑
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describe how blood stabilizes body temperature | show 🗑
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show | 100.4
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how much body weight is due to blood? | show 🗑
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show | 55% of blood, comprised of water (90%), plasma proteins, and fibrinogen
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show | albumin:55-60%, manufactured in liver, maintains water balance, transports fatty acids/thyroid/ steroidal hormones
globulins:35-37%, alpha&beta move hormones/lipids/metals/fat-soluble vitamins; immunoglobulins (gamma) are antibodies
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show | 4-7% of plasma, aid in clotting
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briefly describe the cells of the blood | show 🗑
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what is the difference between plasma and serum? | show 🗑
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describe the origin of blood | show 🗑
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show | red marrow, in the epiphysis of long bones and all short/flat/irregular bones
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show | intrinsic factor, B12, erthyropoietin, reticulo-endothelial organs
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describe the reticulo-endothelial organs | show 🗑
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briefly describe red blood cells | show 🗑
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show | size variation
microcyte: <6, iron deficiency anemia
macrocyte: 9-12, sprue
megalocyte: >12, pernicious anemia
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describe the staining properties of red blood cells | show 🗑
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define poikilocytosis | show 🗑
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show | housed in cell's biconcavity, has a heme portion (oxygen affinity) and a globin-protein portion (carbon dioxide affinity), has 2 alpha and 2 beta chains
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what does -cytosis mean? -cytopenia? | show 🗑
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show | derived from megakaryocyte, which comes from a megakaryoblast, manufactured in red marrow, live 10 days, provide clotting
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how do thrombocytes affect clotting? | show 🗑
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describe the anatomy of thrombocytes | show 🗑
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describe the granules of thrombocytes | show 🗑
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show | live between a few hours to 100 days, carry out phagocytosis, includes granulocytic (parent cell myeloblast) and agranulocytic (parent cell lymphoblast & monoblast) WBCs
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name the granulocytic white blood cells | show 🗑
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describe neutrophils | show 🗑
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show | deep blue cytoplasmic granules, rarest (0-1%), increases with parasitic infections and allergies, resembles mast cells because both release histamine and heparin
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show | large red cytoplasmic granules, bilobated nucleus, 1-5%, increases in allergies and parasitic infestations
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show | lymphocytes, monocytes
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describe lymphocytes | show 🗑
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describe monocytes | show 🗑
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describe the three stages of clotting | show 🗑
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show | wound -> vasoconstriction -> platelet aggregation -> ADP release to increase size and stickiness -> emergency plug formation -> thromboplastin, factor 3 secretion
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describe the second step of the clotting process | show 🗑
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describe the third step of the clotting process | show 🗑
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show | factor 2, produced in liver, requires vitamin K for its manufacture, measured in anticoagulant use (PT)
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show | first step after clotting, the clot retracts from the vessel walls and pulls the tissue together
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describe fibrinolysis | show 🗑
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the presence of absence of ________ is determined by genes | show 🗑
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show | physical expression of a gene
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define genotype | show 🗑
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show | glycoprotein surface antigen found on red blood cells
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show | antibody found in plasma or serum
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show | clumping reaction that occurs between an agglutinin and agglutinogen
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show | forward tests whole blood for agglutinogens, reverse tests serum for agglutinins
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show | 85-89% of people, a surface antigen is present on the red blood cells
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show | no surface antigen is present on the red blood cells
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when would anti-Rh antibodies be formed? | show 🗑
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describe the purpose of Rhogam and when it would be used | show 🗑
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why is type O blood known as a universal donor? | show 🗑
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show | it doesn't have antibodies that would react with a donor's blood
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describe type A blood | show 🗑
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describe type B blood | show 🗑
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show | A and B antigens present on cell surface, neither anti-A nor anti-B antibodies present, compatible with all blood types
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show | neither A nor B antigens present on cell surface, both anti-A and anti-B antibodies present, compatible with only O blood
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describe T and B cells | show 🗑
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