PSYC 3220 Final
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cytoskeleton protein filaments | show 🗑
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show | cytoskeleton protein filament that exists in 2 states: G-actin and F-actin
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show | subunit of actin that serves as a monomer building block and assembles into F-actin
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F-actin (filament actin) | show 🗑
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show | process of combining many monomers into a polymer
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ADF/cofilin (actin-depolymerization factor/cofilin) | show 🗑
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Ser-3 | show 🗑
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show | kinase that phosphorylates the ADF/cofilin site
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adhesion molecules | show 🗑
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neural cadherins | show 🗑
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memory modulation framework | show 🗑
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memory modulators | show 🗑
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epinephrine (EPI, aka. adrenaline) | show 🗑
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adrenoreceptors | show 🗑
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show | an adrenergic neurotransmitter
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show | drugs that mimic the effects of epinephrine
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show | receptors that bind to adrenergics
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propranolol | show 🗑
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show | region of the amygdala that includes the basal and lateral nuclei and is critically involved in memory modulation and storing fear memories and plays and important role in attaching value to outcomes
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nucleus accumbens | show 🗑
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show | frontal part of the cingulate cortex, believed to be involved in modulating memory formation
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show | arises from the medulla and innervates the viscera of the thoracic and abdominal cavities, and carried info about the body into the brain
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NTS (solitary tract nucleus) | show 🗑
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show | adrenal hormone that can modulate memory storage and is classified as a glucocorticoid
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show | hormone involved in the metabolism of glucose and which can directly enter the brain
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show | drug that is a glucocorticoid receptor agonist
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clenbuterol | show 🗑
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show | small region of the brain that contains only about 3,000 neurons but which projects broadly and provides nearly all the norepinephrine to the cortex, limbic system, thalamus, and hypothalamus
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show | syndrome in which individuals have unusually vivid recall of the traumatic events they experienced, accompanied by severe emotional responses
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show | method used to decrease the likelihood that the person who experience a trauma will develop PTSD
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show | brief crisis intervention usually administered within days of a traumatic event in which the trauma-exposed individual is encouraged to talk about his or her feelings and reactions to the event
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active trace theory | show 🗑
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show | theory that assumes that the retrieval of memory itself can disrupt an established memory trace but that the retrieval also initiates another round of protein synthesis so that the trace is "reconsolidated"
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show | amnesia that is more pronounced for recently experienced events that for more remotely experienced events
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standard model of systems consolidation | show 🗑
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show | theory that assumes that a change in the strength of the memory trace is brought about by interactions b/t the MTH system and neocortex and which is assumed to take place over a long period of time, after the memory is initially established
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show | theory of systems consolidation that assumes that the medial temporal hippocampal system is always required to retrieve episodic memories but that semantic memories can become independent of this system
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show | method for imaging regional activity in the brain while the participant is engaged in cognitive activity
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show | method for studying how rodents acquire food preferences from other rodents
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show | system that is organized specifically to ensure that some particular need is met
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show | innate behaviors that are supported by the fear system
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show | measure of fear response in rodents that is dependent upon the distance of a predator; when a potential predator is at a distance a rat will freeze, but when the predator moves within striking distance, a rat might attempt to flee
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PAG (periaqueductal gray) | show 🗑
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show | region of the brain responsible for changes in the autonomic responses produced by the sympathetic nervous system that prepare an animal for action
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amygdala | show 🗑
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show | subnucleus of the CE of the amygdala that is thought to be an important part of the neural basis of fear
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show | subnucelus of the CE of the amygdala thought to be an important part of the neural basis of fear; functions as the output region of the amygdala; when its neurons are activated, they in turn activate neurons in the PAG and LH that generate fear behaviors
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subcortical pathway | show 🗑
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show | pathway that carries info from the sensory thalamus to the neocortical regions of the brain where a richer, more detailed representation of the experience is constructed
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show | region of the brain that supports learned fear to an auditory stimulus by projecting the stimulus directly to the amygdala
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show | autonomic nervous system response related to the skin's ability to conduct electricity, used to measure defensive fear behavior
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instrumental responses (aka. instrumental behavior) | show 🗑
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extinction | show 🗑
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show | hypothesis that assumes extinction is due to the CS-alone presentation eliminating the original CS-US association
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show | hypothesis that assumes extinction produces a new association called a CS-noUS association, which the original CS-US association that produced the CR remains intact
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show | recovery of an habituated response that occurs "spontaneously" with the passage of time
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show | one of several ways to recover an extinguished CR, achieved by changing the context for extinction but later returning an animal to the training context to recover the CR
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show | new association generated when the CS is no longer presented with the US; forms the basis of the competing memory theory in extinction studies
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intercalated neurons | show 🗑
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infralimbic region (aka. infralimbic medial prefrontal cortex) | show 🗑
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show | drug that is a partial agonist and that binds to the glycine site of the NMDA receptor to enhance its opening
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exposure therapy | show 🗑
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