Path 20 Test
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| A. involutional changes with lobular atrophy, related to increase in fatB. Family History, genetics, hormonal status, Radiation exposure, Proliferative breast disease, Dietary fat?C. risk for carcinoma determined by the presence of ductal hyperplasia, especially atypical ductal hyperplasiaD. usually occurs with breast feeding caused by S. aureusE. trauma, response to ruptured cyts in fibrocystic changesF. Invasive lobular carcinomaG. foreign material, mycobacterial infection, sarcoidosis are some etiologiesH. In the ducts within the niple may appear as nipple discharge, erosion, subareolar mass or simulate paget's diseaseI. In situ carcinoma with tumor cells confined within epithelium of the nippleJ. you risk abscess developmentK. degree of differentiation, nuclear atypia, mitotic activity (GRADE IS VERY IMPORTANT FOR PROGNOSIS)L. Puberty, hypogonadism, cirrhosis, estrogen therapyM. Axillary, Internal mammary lymph nodes and supraclavicularN. older average age is 50 (will occur in large ducts in older women and small ducts in younger women)O. central fibroelastotic core with radiated ducts and lobules often with superimposed proliferative changes (benign)P. Worry about both breastsQ. underlying carcinoma (in situ or invasive)R. invasive ductal carcinoma is more likely to present with a massS. Pros: often therapeutic Cons: may not fully excise the lesion, requiring additional surgery, requires anesthesia, may require post operative radiationT. seen in up to 50% of carcinomas commonly present in benign condition |
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