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CANCER
Term | Definition |
---|---|
oncology | study of cancer and their treatment |
etiology | original cause of a cellular alteration |
homeostasis | a condition of equilibrium when various physiologic factors are within normal limits |
allostasis | body's way of adapting to acute stress to maintain homeostasi |
cellular adaption | a protective mechanism to prevent cellular and tissue harm because of stressors |
pathognomonic changes | unique histological findings that represent distinct disease processes |
histology | microscopic study of tissues and cells for diagnostic purposes |
biopsy | extraction of cell samples from an organ or mass of tissue to allow for histological examination |
cellular differentation | the process in which a cell becomes specialized to perform a specific function |
atrophy | a decrease in work demands leading to a shrinkage |
hypertrophy | enlargement of a cell due to excessive use |
hyperplasia | increase in number of cells in an organ tissue, in response to a stimulus |
metaplasia | reversable change where one cell type is replaced with another |
dysplasia | deranged cell growth comes from an irritant, if removed it can be correct, is it a precursor to cancer but is not cancerous |
neoplasia | new growth, tumor |
apoptopsis | programmed cell death, protective process -cells that do not go through apoptosis can lead to cancer |
necrosis | cell death due to injury, irreversible process -initiates inflammatory reaction |
infarction | -ischemic necrosis, death of tissue results from prolonged ischemia (myocardial infarction) |
ischemia | lack of blood supply |
gangrene | -prolonged ischemia, infarction and necrosis -wet: bacteria invades tissue--> swell, odor, oozes -dry: no blood supply, tissue dries and shrinks, turns black |
angiogenesis | formation of new blood vessels |
carcinogenesis | initiation of cancer formation |
benign | abnormal cells that remain localized |
malignant | spread to others area |
adenoma | benign tumor, glandular tissue, or organ |
lipomas | derived from fat cells |
hemangioma | collection of blood vessels in the skin or internal organ |
desmoid tumors | can be highly invasive but do not metastasize |
nevi | non-cancerous moles on the skin |
myomas | muscle tumor |
carcinoma | malignant epithelial cells |
adenocarcinoma | cancer of the glandular or ductal tissue |
sarcoma | mesenchymal origin, such as connective tissue, cartilage, and bone |
leukemia | cancerous change in leukocytes |
lymphoma | cancerous lymphocytes in lymph tissue |
chachexia | progressive loss of body fat and lean mass, essentially the body is being eaten from the inside out |
paraneoplastic syndrome | unexpected pathological disorder provoked by the presence of cancer in the body (not due to cancer's space-occupying or metastatic effects) |
three ways for cancer to metastasize | 1. it is in the blood, moves from its primary site and lands in another tissue and grows there 2. through our lymph system, travels down our lymph nodes 3. surgery contamination |
what is the true diagnostic test for cancer | biopsy |