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NURS 319: Pulmonary
Chapters 20 & 21: Pulmonary and Respiratory Systems
Question | Answer |
---|---|
what parts of the body are involved with breathing? | diaphragm, abdominal muscles, lungs, throat |
what is inhaled in breathing? | oxygen |
what is exhaled in breathing? | carbon dioxide |
what innervates the diaphragm? | C3, C4, C5 |
what does it mean for the ability to breathe if there is damage to the spinal cord? | it can be severely impacted and even cause death |
protective mechanism in the lungs that traps inhaled particles and moves them up to the upper airway to be coughed out | mucociliary apparatus |
what impacts the mucociliary apparatus and how? | respiratory infections and smoking; increased viscosity of mucus |
what are retractions? | pulling inward of soft tissues between ribs upon inhalation |
what are adventitious breath sounds? | superimposed over normal breath sounds; crackles, wheezes, rhonchi, friction rub |
how is breathing controlled? | automatic, controlled by respiratory center in base of brain |
process of diffusion in the airways | oxygen in and carbon dioxide out, acid-base balance, ATP to mitochondria |
where does gas exchange occur? | alveoli |
SaO2 | oxygen saturation of hemoglobin |
oxyhemoglobin | Hgb with attached O2 |
erythropoietin | secreted by kidneys when BP is low |
airway resistance | resistance in respiratory tract to airflow during exhalation and inhalation |
compliance of the lungs | elasticity, expandability, distendibility |
dyspnea | difficulty breathing |
expectoration | expulsion of mucus, sputum, or fluids from the respiratory tract by coughing or clearing one's throat |
hemoptysis | coughing up blood (from lower respiratory) |
ventilation | breathing and its track; expiration: breathing/ pushing out |
perfusion | flow of blood around alveoli through capillaries |
hypoxia | low oxygen in blood |
how does hypoxia affect the vessels? | pulmonary vasoconstriction |
hypercapnia | higher levels of CO2 in blood |
how does hypercapnia affect the vessels? | vasoconstriction |
new stimulus to breathe when the body experiences chronic hypercapnia (allostatic overload) | hypoxia |
atelectasis | collapse of small # of alveoli |
common causes of atelectasis | sedation, shallow breathing, decreased respiratory rate, pneumonia |
anoxia | no oxygen |
carbon monoxide poisoning | hemoglobin has higher affinity for carbon dioxide than oxygen. hemoglobin picks up more co2 than o2. body does not get o2 to muscles, lungs, etc. and gets sick/ shuts down but hemoglobin will continue to carry co2 instead |
why does a person with carbon monoxide poisoning stay pink in color? | formation of carboxyhemoglobin |
respiratory failure | failure to oxygenate blood or remove carbon dioxide |
what would cause a hypoxemic failure? | pulmonary edema, pneumonia PaO2 less than 60 mmHg |
what would cause a hypercapnic failure? | COPD, asthma PaCO2 greater than 50 mmHg |
chest X-rays | takes contrasting image of chest |
pulse oximetry | measures level of O2 saturation |
arterial blood gases | o2 and co2 levels in blood |
CT scan and MRI | more detailed image |
bronchoscopy | scope down to 2nd generation bronchioles |
thoracentesis | remove fluid or air from around the lungs |
sputum cultures | taking sample of patient mucus and running tests on it |
V/Q scan | ventilation and perfusion |
what does mismatch V/Q show? | air cannot flow into an alveolus or blood flow around alveolus is altered |
what is the most common disorder that a V/Q mismatch indicate? | pulmonary embolus |
pulmonary function test | spirometry + lung volumes and air flow |
what is the difference between acute and chronic rhinitis? | length/frequency of inflammation acute: 2-4 days |
symptom of bacterial rhinitis | antibiotics work, more gradual onset |
symptom of viral rhinitis | antibiotics do not work, more rapid onset |
rhinitis | inflammation of mucus membranes |
sinus infection | inflamed sinuses that drain into membranes |
what symptom of a sinus infection would be worrisome and why? (requires hospitalization) | altered mental status/ dizziness indicates that infection has spread to brain |
usual causative agent for bacterial acute pharyngitis | group A beta hemolytic streptococcus |
why do we worry about group A beta hemolytic streptococcus | can cause many life-threatening diseases affects heart, kidneys, lungs |
common symptoms of an infection caused by group A beta hemolytic streptococcus | red, swollen tonsils white exudate on tonsils enlarged lymph nodes |
how do we diagnose bacterial pharyngitis | throat culture/ rapid screening |
is there a difference between acute pharyngitis and acute tonsilitis | acute tonsilitis can be caused by EBV, adenovirus, Herpes simplex virus, cytomegalovirus |
causes and symptoms of tonsilitis | sore throat, fever, difficulty swallowing, erythema, quinsy, swelling of pharynx |
inflammation of the epiglottis | epiglottitis |
key symptoms of acute epiglottitis | infection and inflammation, ABGs, steeple sign, inflamed/red/stiff/ swollen epiglottis |
what must you NOT do when you see a patient with symptoms of acute epiglottitis | keep them calm and do NOT do a throat swab |
what preventative measure can you take to avoid acquiring acute epiglottitis | getting antibiotics in system as soon as possible when sick |
what is acute bronchitis | inflammation of bronchi + bronchioles |
when do we commonly see acute bronchitis | fall and winter |
symptoms for acute bronchitis | sore throat, nasal discharge, muscle aches, persistent cough, fever, sputum (clear, yellow, green, blood-tinged) |
diagnostic criteria for chronic bronchitis | lasts longer than 3 months for 2 consecutive years or more |
which part of the lung is predominately affected by bronchitis | bronchial tubes |
pathophysiology of bronchitis | inflammatory response to pathogen or irritant |
types of pneumonia + key characteristics | community acquired pneumonia: spread rapidly hospital acquired pneumonia: within 48 hours of admission aspiration pneumonia: bacteria in oropharynx mycoplasma pneumonia: walking pneumonia |
pathophysiology of pneumonia | inhalation of droplets |
symptoms of pneumonia | cough, fever/chills, dyspnea, chest pain, hemoptysis, myalgias |
part of the lung predominately affected by pneumonia | lung tissue |
how is pneumonia diagnosed | chest X-ray and sputum culture |
difference between latent and active tuberculosis | latent: dormant active: showing symptoms |
tuberculosis pathophysiology | inhalation of airborne droplets |
how do you test for TB? | skin test + sputum culture |
next test to verify positive TB? | chest X-ray |
what other issues can TB cause? | scrofula, Pott's disease, Addison's disease |
symptoms of active TB | cough, hemoptysis, weight loss, night sweats |
mantoux test and positive looks | skin is viewed immediately then 72 hours later skin splotches bigger than 20mm |
restrictive lung diseases + examples | decrease in total lung capacity pulmonary fibrosis, thoracic cage deformity |
obstructive lung disease + examples | increased resistance to air flow emphysema, COPD, asthma |
primary factor for lung disease | smoking |
secondary (major) risk factor for lung disease | occupational and environmental exposures |
when teaching a patient about lung diseases, what is a major focus of education? | try to stop smoking and avoid exposure if you can |
bronchodilation | dilation of bronchi/ bronchioles |
what part of the nervous system causes bronchodilation | sympathetic ANS |
receptors responsible for bronchodilation | beta-2 adrenergic receptors |
bronchoconstriction | constriction of bronchi/ bronchioles |
what part of the nervous system causes bronchoconstriction | parasympathetic ANS |
chemical mediators that lead to bronchoconstriction | leukotrienes histamine |
where is the pleural membrane | lines chest cavity, envelopes lungs |
why is the pleural membrane important | how lungs expand appropriately |
the pleural membrane is under a ______ ______ pressure which allows the lungs to inflate easily | negative intrathoracic |
accumulation of fluid in the pleural space | pleural effusion |
accumulation of air in the pleural space | pneumothorax |
how does chronic hypercapnia affect chemoreceptors in the brain | headache, drowsiness, intellectual impairment |
what is the level of co2 that is considered hypercapnia | greater than 45 mmHg |
when a patient has chronic hypoxia, what hormone is released to stimulate the production of red blood cells | erythropoietin |
normal po2 level | 75 to 100 mmHg |
po2 level that indicates blood is not perfusing tissues | less than 60 mmHg |
less perfusion of blood to tissues = | increased ventilation |
increased ventilation = | production of erythropoietin |
production of erythropoietin = | pulmonary vasoconstriction |
pulmonary vasoconstriction = | pulmonary hypertension |
pulmonary hypertension = | cor pulmonale |
symptoms you would expect to see in hypoxia | fatigue, clubbing, cyanosis |
what is clubbing and what causes it | rounding of fingernails open ended capillaries from hypoxia |
what is cyanosis and what causes it | blue discoloration of the skin + membranes; excessive concentration of deoxygenated hemoglobin |
3 characteristics to asthma | hyperreactive airway, reversible airway constriction, inflammatory changes |
one thing about asthma that sets it apart from other respiratory illnesses | bronchial remodeling |
how do chronic asthma attacks affect the tissues of the lungs | leads to swelling |
which inflammatory cells play a role in asthma? | histamine, T cells, IgE, leukotrienes, eosinophils |
symptoms of asthma | prolonged expiration, wheezing, cough, dyspnea, chest tightness |
diagnostics of asthma | FVC/ FEV1 ratio diminishes |
classifications of asthma | mild intermittent: flares mild persistent: 2x/wk, interferes with life, persistent bronchodilation despite reversal attempts moderate persistent: receptors saturated severe persistent: continuous symptoms |
what part of the lung does chronic bronchitis affect? | mucus in bronchioles |
chronic bronchitis main issue | hypoxia |
why would a person with chronic bronchitis have elevated hemoglobin | body trying to increase oxygen delivery to lungs |
chronic bronchitis symptoms | clubbing, cough, vasoconstriction, mucus + edema |
what is "blue bloater" | cyanosis and inflammation |
what part of the lung does emphysema affect | alveoli |
emphysema main issue | hypercapnia |
what is "pink puffer" | carbon monoxide overload thin and flat diaphragm |
emphysema symptoms | barrel-shaped chest, prolonged exhalation |
how can chronic bronchitis and emphysema lead to cor pulmonale | overworking right side of heart to compensate |
how COPD can lead to a change in respiratory drive | body adapts to amount of oxygen available |
what would happen if we give a patient too much oxygen and increase their oxygen saturation to 100% with FiO2? | reperfusion injury equivalent; body would be unable to handle it |
pathology of bronchiectasis | bronchiole wall destroyed and replaced by fibrous tissues |
apnea | reduction in airflow by 90% for at least 10 seconds |
difference between obstructive sleep apnea and central sleep apnea | obstructive: upper airway tissues central: loss of respiratory drive from brainstem |
symptoms of sleep apnea | loud snoring, choking/gasping during sleep, unrestful sleep, daytime sleepiness |
sleep apnea diagnosis | sleep study |
pneumothorax | air in pleural space |
primary pneumothorax | tall, young men (30s) |
secondary pneumothorax | long-term emphysema |
traumatic pneumothorax | penetrating wound to ribcage |
tension pneumothorax | compression |
latrogenic pneumothorax | complication of medical procedures |
symptoms of pneumothorax | chest pain, dyspnea, increased respiratory rate |
diagnosis of pneumothorax | chest X-ray, CT scan, pulse oximetry + ABGs |
pleural effusion | fluid in pleural cavity |
pleural effusion symptoms | dyspnea, tachypnea, sharp chest pain, diminished breath sounds |
pleural effusion diagnosis | chest X-ray |
types of environmental lung disease | coal worker, asbestosis, silicosis |
scoliosis | curvature of the spine (sideways) |
kyphosis | curvature of the spine (hunchback) |
how do scoliosis and kyphosis lead to restriction in the lungs | ribcage can shift and crush lungs |
idiopathic pulmonary fibrosis | injury to lung tissue by an unidentified agent |
pulmonary edema | build up of fluid + swelling |
pulmonary edema symptoms | swelling, weight gain, anorexia |
most common cause of pulmonary edema | left ventricular heart failure |
how can a DVT lead to pulmonary embolism | DVT can break off and travel through bloodstream to lungs |
how a V/Q mismatch occurs | perfusion or ventilation is hindered and now ratio does not match |
how does pulmonary hypertension lead to cor pulmonale | R. ventricle hypertrophies and eventually fails because it is overworked |
pathology of adult respiratory distress syndrome | sudden, progressive pulmonary edema |
who do we see ARDS occur in? | critically ill patients |
ARDS symptoms | hypoxemia that does not improve PO2 less than or equal to 50 mmHg PCO2 less than or equal to 50 mmHg |