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Path2 Lec 7 Assgnmt
CanColl May 2012 Path 2 Lec 7 Assgnmt Dec 2011
Question | Answer |
---|---|
Breakdown of a peripheral nervous system (PNS) neuron, distal to the site of injury. | Wallerian degeneration |
Swelling of the neural cell body, which indicates active protein synthesis in an attempt to repair an injured nerve. | Chromatolysis |
Degeneration of a neuron without inciting an inflammatory reaction. | Simple neural atrophy |
Cells responsible for theproduction of new myelin in the PNS | Schwann cells |
True or False: The regeneration of myelin results in complete, normal restoration of nerve impulse transmission. | False - see notes |
List three variations of spina bifida. | occulta, menningocele, myelomenningocele |
Which type of spina bifida is the least (neurologically) problematic? | occulta |
Which type of spina bifida is the most problematic (neurologically)? | myelomenningocele |
Non-communicating hydrocephalus is also known as? | Obstructive |
Non-communicating hyrdrocephalus involves obstruction of which system: vascular or ventricular? | Ventricular |
Obstructive hydrocephalus prevents CSF from reaching what area or structure? | Arachnoid villi |
Communicating hydrocephalus results due to a disruption of the CSF flow: before or after it has exited the ventricular system? | After |
With communicating hydrocephalus, there there is impaired (reabsorption or obstruction) from the arachnoid villi? | reabsorption |
With hydrocephalus, do the ventricles become shrunken or dilated? | dilated |
If hydrocephalus occurs before the skull sutures have formed, what will occur? | enlarged head |
If hydrocephalus results in an enlarged head, are there any intracranial pressure sign present? | No |
Hydrocephalus in adults will cause? | intracranial pressure signs |
The main signs of intracranial pressure are? | Headaches and vomiting |
True or false: Cerebral thrombosis usually has a gradual onset, whereas cerebral embolism usually has a sudden onset. | True |
Herniation of the brainstem & cerebellum thru the foramen magnum is A syringomyelia B hydrocephalus C Arnold-Chiari malformation D subdural hematoma | Arnold-Chiari malformation |
Epidural, Subdural or Subarachnoid? Fracture of the temporal bone. | Epidural |
Epidural, Subdural or Subarachnoid? Bleeding from tearing of the bridging veins affects which system? | Subdural |
Epidural, Subdural or Subarachnoid? develops between the arachnoid and the pia mater | Subarachnoid |
Epidural, subdural or subarachnoid? Develops between the dura and the arachnoid mater | Subdural |
Epidural, Subdural or Subarachnoid? Develops between the skull and the dura mater. | Epidural |
Epidural, Subdural or Subarachnoid? Initially asymptomatic followed by rapid deterioration and prob death in 24 - 48 hrs | Epidural |
Epidural, Subdural or Subarachnoid? Ruptured berry aneurysm. | Subarachnoid |
True or False? For a coup contre-coup head injury, the coup occurs at the site of impact, whereas the contre-coup occurs on the opposite side. | True |
What is the main dif between how ischemic and hemorrhagic strokes occur? | Ischemic - blocked blood vessel = obstruction Hemorrhagic - ruptured blood vessel = bleeding |
A vascular condition in which a capillary bed is lacking:A subdural hematoma B telengiectasia C hydrocephalus D AV malformation | AV Malformation |
The functional unit of the CNS is? | The neuron |
Diseases affecting the axon and the myelin sheath (together) leads to? | Axonal degeneration |
Diseases affecting Schwann cells or the myelin sheath only (not the axon) lead to? | Segmental degeneration |
In segmental degeneration, remyelination can occur - with what results? | The remyelinated area has shorter internodal lengths and the myelin layer is thinner than normal. |
Describe spina bifida. | Spina bifida is a defect in the closure of the posterior aspect of the vertebral column. |
WHat is the most common form of Spina Bifida? | Myelomeningocele |
What is the most common region affected by Syringomelia? | Cervical Spine |
What are the most common signs and symptoms of syringomyelia? | Bilateral loss of pain & temp sensation of upper arms and chest = cape-like sensory deficits. |
Describe Arnold-Chiari Malformation: | Condition in which the brain stem and cerebellum herniate into the formen magnum.(Brain stem says: I'll be back!) |
Obstruction of the flow of CSF in the brain resulting in an accumulation of fluid in the skull is called? | Hydrocephalus |
Pathological changes associated with both types of hydrocephalus? | cerebral hemispheres become enlarged and the ventricle become dilated. |
What can distinguish between acute subdural and epidural hematoma? | With subdural hematoma - the patient does not regain consciousness ( as is usually the case with epidural). It also has a higher mortality rate. |
Describe decerebrate posturing. | arms are rigid and extended with palms turned away from the body & fixed/dilated pupils |
The most common cause of subarachnoid hemorrhage? | Rupture of a berry aneurysm. |
Berry aneurysms are thin-walled outpouchings of the walls of veins or arteries? | Arterial walls |
Where do berry aneurysms commonly occur? | At arterial bifurcation along the circle of Willis. |
Describe the most common site for a berry aneurysm to occur. | At the branching point between the anterior cerebral artery and the anterior communicating artery. (aunt sara ain't communicating) |
Sudden excruciating headache (the worst headache they ever had) is a hallmark for? | Rupture of a berry aneurysm |
Headache, irritability, insomnia, poor concentration and dec memory after a head injury is called? | Postconcussion syndrome |
Often associated with head injuries - a neurological manifestation called aphasia means: | difficulty speaking |
Which cranial nerves innervate the diaphragm? | C3, C4 and C5 - keep the diaphragm alive.... |
Spinal cord injuries. Transection at C1 = | no control of head, neck, diaphragm (require resp ventilation), paralyzed from neck down. No use of arms and legs. |
Spinal cord injuries. Transection at C4 = | good head, neck and diaphragm motor control. Paralyzed from neck down. No arm movement |
Spinal cord injuries. Transection at C8 = | Arms o.k.but paralyzed lower extremities. Paraplegia. |
Spinal cord injuries. Transection at C4 or above = | Quadriplegia |
Describe hemisection of the spinal cord: | partial transection of either the left or right side of the cord. |
Damage of the posterior (dorsal) column (DCML) will produce a loss of: | Proprioception and discriminative touch - on IPSILATERAL side to the injury. |
Damage to the lateral corticospinal track will result in: | Paralysis (lack of motor Fx) - IPSILATERAL to the injury. |
Damage to the spinothalamic tract will produce loss of: | pain & temp sensations - CONTRALATERALLY to the injury |
With spinal cord injury - ipsi paralysis, ipsi loss of proprioception and discrimminative touch along with contra loss of pain & temp = is known as? | Brown-Sequard Syndrome |
The most common and most clinically significant congenital vascular malformation? | AV Malformation |
Lack of capillary bed - means arteries link directly to veins without a buffer. | AV Malformation |
Describe the problem caused by AV malformation. | Direct from hi pressure artery to low pressure veins - predisposes to vascular rupture. |
What types of outcomes are common with AV malformation? | strokes, seizures, headaches, progressive neurologic deficits (e.g. learning disabilities) |
Which is the most common type of stroke? | Ischemic (obstruction) 70 -80% |
Main causes of ischemic stroke? | obstruction by thrombus or embolus |
A clot of blood or formed element that is attached to the wall of the blood vessel - frequently obstructing circulation: | Thrombus |
A clot of blood or other substance that circulates in teh bloodstream until it becomes lodged in a vessel, obstructing the circulation: | Embolus |
The most common symptoms of stroke: | Weakness/sensory impariment of the face, vision disturbances, aphasia, slurred speech, sudden imbalance. |